NCT07340073

Coordinated Reset Deep Brain Stimulation for Parkinson's Disease

• Status: Not Yet Recruiting
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: University of Minnesota · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

Deep brain stimulation (DBS) is a surgical implant procedure for the treatment of Parkinson's Disease (PD) utilizing medical devices approved by the FDA. A novel approach to current DBS approaches is called "Coordinated Reset" DBS (CR-DBS) which uses different patterns of stimulation at lower currents and can address the limitations of traditional DBS (T-DBS) that uses continuous high amplitude and high frequency stimulation. This study will evaluate the safety and short-term efficacy of CR-DBS in PD. The results from this study will significantly advance the development of CR-DBS for the treatment of PD. Findings in this study will also provide the rationale for further development of this novel DBS approach for other neurological and psychiatric disorders.

Conditions

• Parkinson's Disease (PD)
• Deep Brain Stimulation

Interventions

Type	Name	Description
DEVICE	DBS	Deep Brain Stimulation

Timeline

• Start date: 2026-05-01
• Primary completion: 2031-01-01
• Completion: 2031-07-01
• First posted: 2026-01-14
• Last updated: 2026-03-05

Regulatory

• FDA-regulated device study