| Not Yet Recruiting | Drug Eluting Temporary Spur Stent System vs Percutaneous Balloon Angioplasty for the Treatment of Critical Lim NCT06122974 | ReFlow Medical, Inc. | N/A |
| Not Yet Recruiting | Effect of Environmental Temperature on Vascular Ultrasound Vein Scan Measurements NCT06191237 | University Hospital of Limerick | — |
| Recruiting | Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below t NCT04433572 | Mercator MedSystems, Inc. | Phase 3 |
| Recruiting | Use of Thermal Imaging Camera to Assess Perfusion Before and After Vascular Intervention NCT06544135 | University Hospitals Cleveland Medical Center | — |
| Completed | Single Versus Multiple Vessels Endovascular Tibial Arteries Revascularization for Critical Limb Ischemia NCT07383064 | Aswan University | N/A |
| Completed | Medium-term Results of Lower Limb Arterial Bypass NCT07093632 | Hospices Civils de Lyon | — |
| Not Yet Recruiting | Tolerance Study of Allogeneic of Adipose Tissue Derived Mesenchymal Stroma/Stem Cells (AdMSC) Transplantation NCT06795620 | University Hospital, Toulouse | Phase 1 |
| Not Yet Recruiting | Heat Therapy for Peripheral Arterial Disease (HEATPAD) NCT06186505 | Norfolk and Norwich University Hospitals NHS Foundation Trust | N/A |
| Recruiting | Serrantor OCT Study NCT06434194 | Cagent Vascular LLC | N/A |
| Recruiting | TP03HN106 in Patients With Critical Limb Ischemia NCT06482892 | Talengen Institute of Life Sciences, Shenzhen, P.R. China. | Phase 2 |
| Recruiting | Acceleration Time Assessment for Prediction of Critical Limb Ischemia NCT06296576 | Centre Hospitalier le Mans | — |
| Recruiting | Safety and Preliminary Efficacy of Allogeneic Endothelial Progenitor Cells (EPCs) in Patients With Critical Li NCT06359912 | Allife Medical Science and Technology Co., Ltd. | Phase 1 |
| Unknown | Predictive Value of Systolic Rise Time of the Plantar Arch on the Risk of Major Adverse Limb Events (MALE) and NCT06318767 | Centre Hospitalier Universitaire, Amiens | N/A |
| Recruiting | Evaluation of the MAGNITUDE® Bioresorbable Drug-Eluting Scaffold in the Treatment of Patients With Below the K NCT06075940 | R3 Vascular Inc. | N/A |
| Recruiting | Safety, Tolerability, and Biodistribution of [89Zr]Zr-DFO-APAC in Subjects With PAOD/CLI and Healthy Volunteer NCT06204237 | Aplagon Oy | EARLY_Phase 1 |
| Recruiting | Efficacy and Safety of Stempeucel® in Patients With Critical Limb Ischemia (CLI) Due to Peripheral Arterial Di NCT05854641 | Cell Biopeutics Resources Sdn Bhd | Phase 4 |
| Recruiting | Efficacy and Safety of Stempeucel® in Patients With Critical Limb Ischemia (CLI) Due to Buerger's Disease NCT05854615 | Cell Biopeutics Resources Sdn Bhd | Phase 4 |
| Unknown | Pedal Acceleration Time (PAT) as a Measure of Foot Perfusion NCT06007469 | Liverpool University Hospitals NHS Foundation Trust | — |
| Recruiting | IBS Titan™ Sirolimus-eluting Iron Bioresorbable Peripheral Scaffold System Clinical Trial NCT05971394 | Biotyx Medical (Shenzhen) Co., Ltd. | N/A |
| Recruiting | Umbilical Cord Artery-derived Perivascular Stem Cells for the Critical Limb Ischemia Therapy NCT06174597 | Nanjing University | EARLY_Phase 1 |
| Completed | Cost Analysis of Vascular Surgical Techniques NCT06367803 | University Hospital of Limerick | — |
| Recruiting | PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening I NCT05313165 | LimFlow, Inc. | N/A |
| Completed | A Prospective Single-Arm Multicenter StuDy of the BarE TEmporary SPur StEnt System foR the tREatment of Vascul NCT05358353 | ReFlow Medical, Inc. | N/A |
| Unknown | Peri-operative Foot CT Perfusion in CLI Patients NCT05575778 | Fudan University | — |
| Unknown | Evaluation of Tissue Perfusion in Peripheral Arterial Disease (EVTI-PAD) NCT05570019 | Medical University Innsbruck | — |
| Completed | Effect of Acute Cardiovascular Disease on Microbiome NCT05456802 | University Hospital, Essen | — |
| Recruiting | MOTIV BTK Randomized Controlled Trial NCT05406622 | REVA Medical, Inc. | N/A |
| Unknown | The Use of FlowMet-R Technology to Predict Wound Healing in CLI Patients in a Wound Care Center Setting NCT05455554 | Stanford University | — |
| Completed | Diagnostic Tools to Establish the Presence and Severity of Peripheral Arterial Disease in People With Diabetes NCT05009602 | Imperial College London | — |
| Recruiting | CRUSH PAD: Real-world Outcomes Following Use of Shockwave Intravascular Lithotripsy (IVL) Technology in Calcif NCT05145478 | Yale University | — |
| Unknown | Serranator Recoil Study NCT05161039 | Cagent Vascular LLC | N/A |
| Recruiting | Prospective Cohort of Patients With Critical Limb Ischemia Undergoing Revascularization NCT04312451 | Fondation Hôpital Saint-Joseph | — |
| Completed | Imaging-Guided Vessel Sizing in the Tibial Arteries NCT04748965 | University Hospitals Cleveland Medical Center | — |
| Unknown | Retrograde Recanalization of Infrainguinal Arterial Occlusive Disease. NCT04974905 | Sohag University | N/A |
| Terminated | YQ23 Study in Patients With Critical Limb Ischaemia NCT04792008 | New Beta Innovation Limited | Phase 1 / Phase 2 |
| Unknown | Autologous Fat Grafting in the Treatment of Critical Limb Ischaemia NCT04746599 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | N/A |
| Completed | Efficacy and Safety of Mesenchymal Stem Cell Clusters in Patients with Critical Limb Ischemia NCT04661644 | S.Biomedics Co., Ltd. | Phase 1 / Phase 2 |
| Unknown | Comparison of Sirolimus vs Paclitaxel Drug Eluting Balloon for Below-the-knee Angioplasty in Critical Limb Isc NCT04594889 | Ospedale San Donato | N/A |
| Unknown | Efficacy and Safety Comparison of the Open and Endovascular Surgical Methods for the Treatment of Long Atheros NCT04583436 | Meshalkin Research Institute of Pathology of Circulation | N/A |
| Unknown | Investigating the Safety and Efficacy of the Treatment With the Non-compliant Jade Balloon in TASC C and D Ath NCT04534192 | Singapore General Hospital | N/A |
| Unknown | The CLI-AMP Registry NCT04427124 | Hendrick Medical Center | — |
| Completed | Continuous Sciatic Block Nerve in the Management of Vascular Pain in Critical Ischemia of Lower Limbs Patients NCT04278014 | Universidad de Antioquia | — |
| Completed | The Impact of COVID-19 Pandemic on Critical Limb Threatening Ischemia and Emergency Vascular Practice NCT04452682 | Mansoura University | — |
| Unknown | Alprostadil as an Adjuvant Therapy With Indirect Angiosomal Revascularization in Critical Limb Ischemia. NCT04312555 | Assiut University | Phase 4 |
| Unknown | Drug-Eluting Balloon Angioplasty Versus Bypass Surgery as First-Line Strategies in Infrageniculate Arterial Di NCT04760119 | Lithuanian University of Health Sciences | N/A |
| Completed | Natural Progression of High-Risk Chronic Limb-Threatening Ischemia: The CLariTI Study NCT04304105 | LimFlow, Inc. | — |
| Unknown | Effect of Evolocumab in Patients With Critical Limb Ischemia (Evol-CLI) NCT04306471 | Leonardo Clavijo | Phase 4 |
| Completed | A Study of the TEmporary Spur StEnt System for the Treatment of Lesions Located in the InfraPoplitEal ARteries NCT04162418 | ReFlow Medical, Inc. | N/A |
| Completed | New Oxymetry Indices in Critical Limb Ischemia NCT04209998 | University Hospital, Angers | — |
| Unknown | Efficacy and Safety of Apixaban in Reducing Restenosis and Limb Loss in PAD Patients. NCT04229264 | Science Valley Research Institute | Phase 3 |
| Completed | SCOPE CLI (Shifting Care and Outcomes for Patients With Endangered Limbs - Critical Limb Ischemia) NCT03171259 | Saint Luke's Health System | — |
| Unknown | Platelet Reactivity in PAD Undergoing Percutaneous Angioplasty NCT04165629 | Clinical Centre of Serbia | — |
| Unknown | Revascularization of Stenosed Vessels Using Optimized Treatment of Rejuveinix for Reversing Endothelial Dysfun NCT03041259 | Reven Pharmaceuticals, Inc. | Phase 1 / Phase 2 |
| Completed | The PRELUDE BTK Study NCT03693963 | Cagent Vascular LLC | N/A |
| Completed | Percutaneous Deep Vein Arterialization Post-Market Study NCT03807661 | LimFlow SA | N/A |
| Completed | BEST vCLI Registry NCT04191746 | Duke University | — |
| Unknown | PROMISE II: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Is NCT03970538 | LimFlow, Inc. | N/A |
| Withdrawn | A Safety and Efficacy Study of Autologous Bone Marrow Derived Mesenchymal Stem Cells in Critical Limb Ischemia NCT02477540 | Pharmicell Co., Ltd. | Phase 1 |
| Unknown | LegDeb2 Global Registry for Use of Legflow in Peripheral Arteries NCT04175197 | Federico II University | — |
| Completed | Investigating the Safety and Efficacy of the Treatment With the Selution Sirolimus Coated Balloon in TASC C an NCT04071782 | Singapore General Hospital | N/A |
| Unknown | Evaluation of Safety and Tolerability of Libella Gene Therapy for Critical Limb Ischemia: AAV- hTERT NCT04110964 | Libella Gene Therapeutics | Phase 1 |
| Unknown | MOTIV Bioresorbable Scaffold in BTK Artery Disease NCT03987061 | Dr. Sabrina Overhagen | N/A |
| Unknown | Cell Therapy in Critical Limb Ischemia NCT03994666 | CHU de Reims | Phase 2 |
| Recruiting | FAZA PET/MRI in CLI Patients Pre and Post Revascularization NCT04054609 | University Health Network, Toronto | N/A |
| Terminated | Intermittent Negative Pressure; Impact on Peripheral Artery Disease and Intermittent Claudication NCT04100681 | Otivio AS | N/A |
| Completed | Exercise In Critical Limb Ischaemia Patients Having Surgery Proof of Concept NCT04043078 | Hull University Teaching Hospitals NHS Trust | N/A |
| Terminated | HemaTrate™ in the Treatment of Critical Limb Ischemia NCT03809494 | Cook Research Incorporated | N/A |
| Recruiting | Leg Ischaemia Management Collaboration NCT04027244 | University of Leicester | — |
| Recruiting | Trial to Assess Chelation Therapy in Critical Limb Ischemia NCT03982693 | Mt. Sinai Medical Center, Miami | Phase 3 |
| Completed | TEsting for Arterial Disease in Diabetes (TrEAD) Study NCT04058626 | Imperial College Healthcare NHS Trust | — |
| Unknown | Exercise Rehabilitation for Patients With Critical Limb Ischemia After Revascularization NCT03839953 | University of Calgary | N/A |
| Unknown | Foot Perfusion Analysis to Predict Limb Salvage NCT03810469 | Centre Hospitalier de Valenciennes | — |
| Unknown | Evaluation of Post-Angioplasty Outcomes NCT05018949 | Singapore General Hospital | — |
| Unknown | Excimer Laser Combined With DCB Compared With Angioplasty Alone in the Treatment of Infrapopliteal Lesions. NCT04365075 | Xuanwu Hospital, Beijing | N/A |
| Completed | Investigating the Safety and Efficacy of the Treatment With Luminor DCB and Angiolite DES of iVascular in TASC NCT04073121 | Singapore General Hospital | N/A |
| Unknown | Critical Limb Ischemia and Transcutaneous Oximetry NCT04369781 | University Hospital, Angers | — |
| Recruiting | Nutrition in Patient With Critical Limb Ischemia NCT03529019 | Boston Medical Center | EARLY_Phase 1 |
| Unknown | Treatment of No-option CLI by G-CSF-mobilized PB-MNC NCT03686228 | Mahidol University | N/A |
| Unknown | Recombinant SeV-hFGF2/dF Injection for PAOD NCT03668353 | Shenzhen Salubris Pharmaceuticals Co., Ltd. | Phase 1 |
| Completed | The DES BTK Vascular Stent System vs PTA in Subjects With Critical Limb Ischemia NCT03551496 | Boston Scientific Corporation | Phase 3 |
| Completed | A Safety and Tolerability Study of RJX Drug Product in Healthy Participants NCT03680105 | Reven Pharmaceuticals, Inc. | Phase 1 |
| Completed | Laboratory, Cellular and Molecular Determinants of Clinical Success in Diabetic Patients With Critical Limb Is NCT03636867 | Maria Cecilia Hospital | — |
| Recruiting | Additional Hyperbaric Oxygen After Lower Extremity Amputation NCT03594344 | Oslo University Hospital | N/A |
| Unknown | Cardiovascular Clinical Project to Evaluate the Regenerative Capacity of CardioCell in Patients With No-option NCT03423732 | John Paul II Hospital, Krakow | Phase 2 / Phase 3 |
| Unknown | RECCORD (Recording Courses of Vascular Diseases) Registry NCT03448029 | Deutsche Gesellschaft für Angiologie, Gesellschaft für Gefäßmedizin e.V. | — |
| Completed | PROMISE International NCT03321552 | LimFlow SA | N/A |
| Completed | Study to Assess the Efficacy and Safety of CLBS12 in Patients with Critical Limb Ischemia (CLI) NCT02501018 | Lisata Therapeutics, Inc. | Phase 2 |
| Completed | Feasibility Clinical Trial Using the SPUR System to Demonstrate Safety and Efficacy. NCT03669458 | ReFlow Medical, Inc. | N/A |
| Terminated | Diamondback in Peripheral Vascular Disease NCT03455374 | Arkansas Heart Hospital | N/A |
| Completed | PROMISE I Early Feasibility Trial of the LimFlow Stent Graft System NCT03124875 | LimFlow, Inc. | N/A |
| Completed | Open Versus Endovascular Revascularization in Patients With End-stage Renal Disease NCT03293589 | University Hospital Erlangen | — |
| Suspended | Stellarex DCB Versus Standard Balloon Angioplasty for Treatment of Below-The-Knee (BTK) Arteries NCT03175744 | Spectranetics Corporation | N/A |
| Withdrawn | Correlation Between FlowMet™ and Other Gold Standard Assessments in the Management of Critical Limb Ischemia ( NCT03094559 | The Cleveland Clinic | N/A |
| Completed | IN.PACT BTK Randomized Study to Assess Safety and Efficacy of IN.PACT 014 vs. PTA NCT02963649 | Medtronic Endovascular | N/A |
| Completed | N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes NCT03253328 | Washington University School of Medicine | EARLY_Phase 1 |
| Unknown | Comparison of Cilostazol-based Triple Antiplatelet Therapy Versus Dual Antiplatelet Therapy for Outcomes of be NCT02829151 | Yonsei University | Phase 4 |
| Completed | A Long Term Follow-up Study of AMG0001 in Subjects With Critical Limb Ischemia NCT02974179 | AnGes USA, Inc. | — |
| Withdrawn | Autologous BMMNC Combined With HA Therapy for PAOD NCT03214887 | Academia Sinica, Taiwan | Phase 1 / Phase 2 |
| Completed | Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation NCT02863926 | Michael Murphy | Phase 1 |
| Unknown | Effectiveness and Safety of Adipose-Derived Regenerative Cells for the Treatment of Critical Lower Limb Ischem NCT02864654 | Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation | Phase 1 / Phase 2 |
| Terminated | Plerixafor in Diabetic Wound Healing NCT02790957 | Gian Paolo Fadini | Phase 2 |
| Completed | Proteomics and Stem Cell Therapy as a New Vascularization Strategy NCT02802852 | University of Illinois at Chicago | N/A |
| Recruiting | miRNAs in Critical Limb Ischemia (miRNACLI) NCT06066268 | IRCCS Policlinico S. Donato | — |
| Completed | Intima Versus Adventitia Drug Delivery to Elucidate Mechanisms of Restenosis: Magnetic Resonance Imaging NCT02807779 | University of California, San Francisco | Phase 4 |
| Completed | BOLD MRI as a Surrogate of Improved Muscle Oxygenation Following Endovascular Therapy for the Treatment of CLI NCT02601430 | Zimmer Biomet | N/A |
| Completed | Phoenix Post-Approval Registry - Using the Phoenix Atherectomy Systems NCT02475200 | Volcano Corporation | — |
| Unknown | Drug Eluting Balloons PTA in Infra-popliteal Arteries in Patients With Critical Limb Ischemia NCT02498080 | Neuromed IRCCS | N/A |
| Completed | Elutax-SV Drug-eluting Balloons for Below-the-knee Treatment NCT02539940 | Jena University Hospital | — |
| Unknown | Comparison of Prevena Negative Pressure Incision Management System vs. Standard Dressing After Vascular Surger NCT02389023 | University of Vermont Medical Center | N/A |
| Completed | Chelation Therapy in Diabetic Patients With Critical Limb Ischemia NCT03424746 | Mt. Sinai Medical Center, Miami | EARLY_Phase 1 |
| Completed | Cell Therapy With Mesenchymal Stem Cell in Ischemic Limb Disease NCT02336646 | Taiwan Bio Therapeutics Inc. | Phase 1 |
| Completed | Autologous Stem Cells for the Treatment of No Option Critical Limb Ischemia NCT03455335 | National University of Ireland, Galway, Ireland | Phase 1 |
| Completed | The COPPER-B Trial NCT02395744 | Horizons International Peripheral Group | N/A |
| Terminated | Efficacy and Safety of AMG0001 in Subjects With Critical Limb Ischemia NCT02144610 | AnGes USA, Inc. | Phase 3 |
| Active Not Recruiting | Swedish Drug-elution Trial in Peripheral Arterial Disease NCT02051088 | Sahlgrenska University Hospital | N/A |
| Completed | Pilot Study to Examine the Use of Rivaroxaban After Angioplasty for Critical Limb Ischemia NCT02260622 | Ottawa Hospital Research Institute | Phase 2 |
| Unknown | Evaluation of Carbothera in the Treatment of Foot Ulcers NCT02239419 | University of Manitoba | N/A |
| Unknown | To Evaluate the Safety and Efficacy of IM and IV Administration of Autologous ADMSCs for Treatment of CLI NCT02145897 | Kasiak Research Pvt. Ltd. | Phase 1 / Phase 2 |
| Unknown | Evaluation of the Tissue Genesis® Icellator Cell Isolation System™ to Treat Critical Limb Ischemia NCT02234778 | Tissue Genesis | N/A |
| Completed | Best Endovascular vs. Best Surgical Therapy in Patients With Critical Limb Ischemia NCT02060630 | Carelon Research | N/A |
| Completed | ACP-01 in Patients With Critical Limb Ischemia NCT02551679 | Hemostemix | Phase 2 |
| Completed | Drug Eluting Balloon Angioplasty Versus Nitinol Stent Implantation in the Superficial Femoral Artery NCT02212470 | Instituto Dante Pazzanese de Cardiologia | Phase 4 |
| Completed | Pilot Safety Study of Injectable SIS for Critical Limb Ischemia NCT02145845 | Cook Group Incorporated | N/A |
| Completed | Platelet Activity in Vascular Surgery and Cardiovascular Events NCT02106429 | NYU Langone Health | — |
| Withdrawn | Autologous Adipose-Derived Stromal Cell Delivered Via Intramuscular Injections for the Treatment of Critical L NCT02099500 | Ageless Regenerative Institute | Phase 1 |
| Completed | Switch to Ticagrelor in Critical Limb Ischemia Anti-platelet Study NCT02091921 | University of Southern California | Phase 1 / Phase 2 |
| Completed | Autologous Peripheral Blood Mononuclear Cells in Diabetic Foot Patients With No-option Critical Limb Ischemia NCT04255004 | Ospedale San Donato | N/A |
| Completed | Tack Optimized Balloon Angioplasty Below the Knee (TOBA - BTK) Study NCT02235675 | Philips Clinical & Medical Affairs Global | N/A |
| Completed | A Phase IIB Pilot Study of a Modified Dosage Regimen of AMG0001 in Subjects With Critical Limb Ischemia NCT02016755 | AnGes USA, Inc. | Phase 2 |
| Unknown | External Compression Therapy for Secondary Prevention of Lower-Limb Loss and Cardiovascular Mortality NCT02054416 | Temple University | N/A |
| Unknown | Allogeneic Mesenchymal Stem Cells for the Critical Limb Ischemia Therapy NCT03239535 | Federal Research Clinical Center of Federal Medical & Biological Agency, Russia | Phase 1 / Phase 2 |
| Unknown | Evaluating the Effectiveness of Paclitaxel-eluting Balloons for Below-the-knee Angioplasty in Patients With Cr NCT01938872 | Ospedale San Donato | — |
| Terminated | Dissolved Oxygen Dressing to Improve Chronic Wound Healing After Revascularization for Critical Limb Ischemia NCT02046226 | Halyard Health | N/A |
| Completed | Drug Impregnated Bioabsorbable Stent in Asian Population Extremity Arterial Revascularization (DISAPEAR Study) NCT02043795 | Changi General Hospital | N/A |
| Completed | Aspirin and Clopidogrel Reactivity in Patients With Critical Limb Ischemia (CLI) NCT02094755 | University of Southern California | — |
| Completed | Lutonix DCB Versus Standard Balloon Angioplasty for Treatment of Below-The-Knee (BTK) Arteries NCT01870401 | C. R. Bard | N/A |
| Completed | Study to Assess Efficacy and Safety of Bone Marrow Derived Stem Cells in Patients With Critical Limb Ischemia NCT01867190 | Lifecells, LLC. | Phase 2 |
| Completed | Treatment of Chronic Critical Limb Ischemia With G-CSF-mobilized Autologous Peripheral Blood Mononuclear Cells NCT01833585 | Mahidol University | Phase 3 |
| Completed | Treatment of PAD by Platelet Lysate for Therapeutic Angiogenesis NCT02941419 | University of Jordan | Phase 1 / Phase 2 |
| Completed | Complete Lesion Assessment With ffR and IVUS TechnologY NCT01941030 | Abbott Medical Devices | N/A |
| Completed | Cryopreserved Saphenous Vein Allograft in Patients With Critical Limb Ischemia for Peripheral Revascularizatio NCT01799811 | CryoLife, Inc. | — |
| Completed | Peripheral Registry of Endovascular Clinical Outcomes "The PRIME Registry" NCT02786173 | Metro Health, Michigan | — |
| Completed | Registry of First-line Treatments in Patients With Critical Limb Ischemia NCT01877252 | St. Franziskus Hospital | — |
| Completed | Self-Expanding Nitinol Stent Versus Balloon Angioplasty Alone for the Below The Knee Arteries(SENS-BTK) NCT01644487 | Korea University Guro Hospital | N/A |
| Completed | Tibiopedal Access for Crossing of Infrainguinal Artery Occlusions NCT01609621 | Cook Group Incorporated | — |
| Completed | Study to Evaluate the Safety and Efficacy of JVS-100 Administered to Adults With Critical Limb Ischemia NCT01410331 | Juventas Therapeutics, Inc. | Phase 2 |
| Completed | An Efficacy and Safety Study of Ixmyelocel-T in Patients With Critical Limb Ischemia (CLI) NCT01483898 | Vericel Corporation | Phase 3 |
| Completed | Laser Atherectomy Versus Angioplasty for the Treatment of Critical Limb Ischemia NCT01579123 | Baylor Research Institute | N/A |
| Completed | Matrix Metalloproteinases in Patients With Critical Limb Ischemia Undergoing Surgical Revascularization NCT02388867 | University of Catanzaro | N/A |
| Completed | A Clinical Trial to Study the Efficacy and Safety of Different Doses of Bone Marrow Derived Mesenchymal Stem C NCT01484574 | Stempeutics Research Pvt Ltd | Phase 2 |
| Terminated | The ABSORB BTK (Below The Knee) Clinical Investigation NCT01341340 | Abbott Medical Devices | N/A |
| Completed | Prospective Observation Study of Outcome of Interventions for Critical Ischemia NCT01794494 | Sahlgrenska University Hospital | — |
| Unknown | Safety and Efficacy Study of Autologous BM-MNC Processed by Two Methods for Treating Patients With Chronic Lim NCT01446055 | Xuanwu Hospital, Beijing | Phase 1 / Phase 2 |
| Completed | Near Infrared Spectroscopy and Transcutaneous Oxygen Pressure in Critical Limb Ischemia Before and After Treat NCT01459341 | Carmel Medical Center | — |
| Terminated | Safety and Efficacy Study of Urokinase for the Treatment of Diabetic Foot Syndrome and Critical Limb Ischemia NCT01638585 | GWT-TUD GmbH | Phase 3 |
| Completed | Bone Marrow Aspirate Concentrate (BMAC) for Treatment of Critical Limb Ischemia (CLI) NCT01245335 | Harvest Technologies | Phase 3 |
| Completed | Tolerability and Efficacy of Intravenous Infusion of Autologous MSC_Apceth for the Treatment of Critical Limb NCT01351610 | Apceth GmbH & Co. KG | Phase 1 / Phase 2 |
| Unknown | Intramuscular Mononuclear Cells and Mesenchymal Stem Cells Transplantation to Treat Chronic Critical Limb Isch NCT01456819 | National University of Malaysia | Phase 2 |
| Completed | Safety and Efficacy of Autologous Bone Marrow Mononuclear Cells in Patients With Severe Critical Limb Ischemia NCT01472289 | TotipotentSC Scientific Product Pvt. Ltd. | Phase 1 / Phase 2 |
| Completed | Application of Cell Regeneration Therapy With Mesenchymal Stem Cells From Adipose Tissue in Critical Chronic I NCT01745744 | Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud | Phase 2 |
| Unknown | Umbilical Cord Mesenchymal Stem Cells Injection for Diabetic Foot NCT01216865 | Qingdao University | Phase 1 / Phase 2 |
| Completed | Drug Eluting Balloon in peripherAl inTErvention For Below The Knee Angioplasty Evaluation NCT01558505 | Leonardo Bolognese, MD | Phase 4 |
| Completed | Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia NCT01064440 | Helixmith Co., Ltd. | Phase 2 |
| Terminated | Register for Patients With Diabetic Foot Syndrome and Critical Limb Ischemia NCT01599442 | GWT-TUD GmbH | — |
| Terminated | Safety and Efficacy Study of Autologous Concentrated Bone Marrow Aspirate (cBMA) for Critical Limb Ischemia (C NCT01049919 | Zimmer Biomet | N/A |
| Active Not Recruiting | Safety Study of MultiGeneAngio in Patients With Chronic Critical Limb Ischemia NCT00956332 | MultiGene Vascular Systems Ltd. | Phase 1 / Phase 2 |
| Completed | Safety & Feasibility Study of Tack-It Device for Vessel Dissection Repair NCT02044003 | Philips Clinical & Medical Affairs Global | N/A |
| Terminated | Efficacy and Safety of Umbilical Cord Blood Injection for Critical Limb Ischemia NCT01019681 | Richard Burt, MD | Phase 1 |
| Completed | Monocentric Trial: Stem Cell Emergency Life Threatening Limbs Arteriopathy (SCELTA) NCT02454231 | University of Florence | Phase 2 / Phase 3 |
| Unknown | Distal Venous Arterialisation of Ischemic Limb NCT01211925 | Clinical Centre of Serbia | Phase 2 / Phase 3 |
| Completed | Safety of Intramuscular Injections (IM) of Allogeneic PLX-PAD Cells for the Treatment of Critical Limb Ischemi NCT00951210 | Pluristem Ltd. | Phase 1 |
| Unknown | A Clinical Trial on Diabetic Foot Using Peripheral Blood Derived Stem Cells for Treating Critical Limb Ischemi NCT00922389 | Beike Biotech India Pvt.ltd | Phase 1 / Phase 2 |
| Completed | Safety of Intramuscular Injection of Allogeneic PLX-PAD Cells for the Treatment of Critical Limb Ischemia NCT00919958 | Pluristem Ltd. | Phase 1 |
| Terminated | Safety Study of Adult Stem Cells to Treat Patients With Severe Leg Artery Disease NCT00913900 | University of Wisconsin, Madison | Phase 1 |
| Completed | Study of SilverHawk®/TurboHawk® in Lower Extremity Vessels (DEFINITIVE™ LE) NCT00883246 | Medtronic Endovascular | N/A |
| Completed | Mesenchymal Stem Cells in Critical Limb Ischemia NCT00883870 | Stempeutics Research Pvt Ltd | Phase 1 / Phase 2 |
| Terminated | Use of Clearway™ Balloon vs. Mechanical Thrombectomy as Initial Treatment for Acute Limb Ischemia NCT00869375 | University of Oklahoma | N/A |
| Unknown | Diabetic Foot and Vascular Progenitor Cells NCT01269580 | IRCCS Multimedica | — |
| Completed | Feasibility of Peripheral Angioplasty in Type D TASCII Lesions NCT01297387 | IRCCS Multimedica | — |
| Completed | Autologous Endothelial Progenitor Cells (EPCs) From Peripheral Blood in the Treatment of Critical Limb Ischemi NCT01595776 | Fondazione IRCCS Policlinico San Matteo di Pavia | Phase 1 / Phase 2 |
| Completed | Safety and Effect of Adipose Tissue Derived Mesenchymal Stem Cells Implantation in Patients With Critical Limb NCT01663376 | R-Bio | N/A |
| Completed | Efficacy Study of Iliac Stents to Treat TASC A-B-C-D Iliac Artery Lesions NCT00764777 | Flanders Medical Research Program | Phase 4 |
| Unknown | Study of the Clinical Efficacy of Autologous SCT in Patients With Critical Limb Ischemia NCT01311011 | King Faisal Specialist Hospital & Research Center | — |
| Completed | Autologous Bone Marrow Stem Cell Transfer in Patients With Chronical Critical Limb Ischemia and Diabetic Foot NCT01232673 | University Hospital Ostrava | Phase 2 |
| Unknown | Validation of OxyVu for Assessing Level of Amputation With Comparison to Other Modalities NCT00767923 | HyperMed | — |
| Completed | Phase II Combination Stem Cell Therapy for the Treatment of Severe Leg Ischemia NCT00721006 | TCA Cellular Therapy | Phase 2 |
| Completed | Autologous Angiogenic Cell Precursors (ACPs) for the Treatment of Peripheral Artery Disease NCT01584986 | Salus Ltd. | Phase 2 |
| Completed | Drug Eluting Stents In The Critically Ischemic Lower Leg NCT00510393 | Flanders Medical Research Program | Phase 2 |
| Completed | Safety Study of UT-15C SR (Oral Treprostinil) in Patients Undergoing a Lower Limb Endovascular Procedure NCT00651885 | Ochsner Health System | Phase 2 |
| Completed | DURABILITY-200: EverFlex 200mm Long Nitinol Stents in TASC C&D Femoropopliteal Lesions NCT00637741 | Flanders Medical Research Program | Phase 4 |
| Unknown | Assessing Best Medical Treatment Patterns of Patients With Symptomatic Peripheral Arterial Occlusive Disease i NCT03909022 | Universitätsklinikum Hamburg-Eppendorf | — |
| Completed | Injection of Autologous CD34-Positive Cells for Critical Limb Ischemia NCT00616980 | Losordo, Douglas, M.D. | Phase 1 / Phase 2 |
| Completed | Combination Stem Cell Therapy for the Treatment of Severe Leg Ischemia NCT00518401 | TCA Cellular Therapy | Phase 1 |
| Completed | Cryoplasty CLIMB-registry NCT00459888 | Flanders Medical Research Program | Phase 4 |
| Completed | Safety Study of Gene Therapy in Treating Critical Leg Ischemia NCT00696124 | Helixmith Co., Ltd. | Phase 1 |
| Completed | A Retrospective Analysis of Patients With Full Thickness Wounds in Limbs With Critical Ischemia NCT00760357 | Southwest Regional Wound Care Center | — |
| Unknown | UT-15C SR in the Treatment of Critical Limb Ischemia NCT00445159 | Southern Arizona Vascular Institute | Phase 2 |
| Completed | ALD-301 for Critical Limb Ischemia, Randomized Trial NCT00392509 | Aldagen | Phase 1 / Phase 2 |
| Completed | Study to Explore the Effect of Lowering Blood Viscosity in Patients With Treatment-resistant Critical Limb Isc NCT01758874 | Seoul Veterans Hospital | Phase 2 |
| Terminated | Randomized Study of Pregabalin for Pain Reduction in Patients With Rest Pain and Lower Limb Ischemia NCT00403780 | Karolinska Institutet | Phase 4 |
| Unknown | Stem Cells for Treating Critical Ischemia NCT00488020 | Instituto de Molestias Cardiovasculares | Phase 1 |
| Completed | ACPs in Severe PAD/CLI by Direct Intramuscular Injection NCT00523731 | TheraVitae Ltd. | Phase 1 |
| Terminated | Study of Remodulin in Patients With Critical Limb Ischemia With No Planned Revascularization Procedures NCT00060996 | United Therapeutics | Phase 3 |
| Completed | Impact of Critical Limb Ischemia on Long Term Cardiac Mortality in Diabetic Patients Undergoing Percutaneous C NCT01676519 | Ospedale San Donato | — |
| Completed | Revascularization in Nonagenarian Patients With Critical Lower Limb Ischaemia NCT02517840 | Hospital Universitario Getafe | — |
| Completed | Scandinavian Miller Collar Study NCT01285986 | University Hospital, Linkoeping | N/A |
| Completed | Swedish External Support Study NCT01273740 | University Hospital, Linkoeping | N/A |
| Completed | Choice of Material for Above-Knee Femoro-Popliteal Bypass Prosthetic Graft (PopUp) NCT00300690 | University Hospital, Gentofte, Copenhagen | Phase 4 |
| No Longer Available | Safety and Efficacy of Autologous Concentrated Bone Marrow Aspirate for Critical Limb Ischemia - Continued Acc NCT02474121 | Zimmer Biomet | — |
| Completed | VEGF Gene Transfer for Critical Limb Ischemia NCT00304837 | Losordo, Douglas, M.D. | Phase 1 |