Clinical Trials Directory

Trials / Terminated

TerminatedNCT01599442

Register for Patients With Diabetic Foot Syndrome and Critical Limb Ischemia

Status
Terminated
Phase
Study type
Observational
Enrollment
123 (actual)
Sponsor
GWT-TUD GmbH · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Diabetic foot syndrome (DFS) is a disease caused by neurogenic (concerning the nervous system), vascular, mechanic and metabolic factors, which are further complicated by an impairment of the immune system and a corresponding increase in the risk for infections. Results from clinical trials about the efficacy of interventions aimed at reducing the number of patient-relevant end points are of limited comparability due to the heterogenity of patient characteristics. By their very nature, randomized clinical trials (RCT) can only focus on a limited section of the wide range of possible intervention regimes. In clinical practice, however, a number of patients with dfs will never have been part of a clinical trial. Furthermore, there are only very few contemporary registers for this indication from which conclusions with regard to the comparative merits of different therapeutic strategies may be drawn. The register was conceived to find out to which extent RCT patients are representative for the overall patient collective with dfs and critical limb ischemia and to evaluate the therapeutic success of other treatment strategies. An RCT to assess the efficacy of urokinase versus placebo is imbedded in the register.

Detailed description

August-1 is a register to find out to which extent RCT patients are representative for the overall patient collective with dfs and critical limb ischemia and to evaluate the therapeutic success of other treatment strategies. An RCT to assess the efficacy of urokinase versus placebo is imbedded in the register.

Conditions

Timeline

Start date
2010-06-01
Primary completion
2013-07-01
Completion
2013-07-01
First posted
2012-05-16
Last updated
2014-04-07

Locations

1 site across 1 country: Germany

Source: ClinicalTrials.gov record NCT01599442. Inclusion in this directory is not an endorsement.