| Not Yet Recruiting | Follow-up Compliance for Corneal Ulcer Patients With SMS Reminder NCT07377513 | Seva Canada Society | N/A |
| Recruiting | Intrastromal Moxifloxacin as an Adjunctive Therapy in Recalcitrant Bacterial Keratitis NCT07394257 | Minia University | N/A |
| Recruiting | Fungal Ulcer Treatment Augmented With Natamycin and Cyclosporine A NCT06658002 | University of California, San Francisco | Phase 3 |
| Withdrawn | Open-label Trial to Evaluate Efficacy and Safety of rhNGF on Corneal Thickness Via AS-OCT in Neurotrophic Kera NCT06411145 | Dompé Farmaceutici S.p.A | Phase 4 |
| Recruiting | Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells NCT05705024 | University of Illinois at Chicago | Phase 2 |
| Unknown | Topical Insulin in Neurotrophic Keratopathy After Diabetic Vitrectomy NCT05940376 | Benha University | — |
| Completed | AONDA Therapeutic Indication Study I NCT05891106 | Alcon Research | — |
| Withdrawn | Use of a Biological Lens of Amniotic Membrane (LV-Visio-AMTRIX) in the Treatment of Trophic Ulcers NCT05172349 | TBF Genie Tissulaire | Phase 2 |
| Unknown | Effect of Various Treatment Modalities on Dendritic Vial Ulcer NCT05313828 | Sohag University | — |
| Unknown | Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Previously Untreated Corn NCT05255107 | Peschke GmbH | Phase 2 / Phase 3 |
| Unknown | Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Refractory Corneal Ulcers NCT05255016 | Peschke GmbH | Phase 2 / Phase 3 |
| Completed | Improving the Follow up Rate for Pediatric Patients NCT04837534 | Seva Foundation | N/A |
| Completed | ACRO Biocornea Clinical Trial in Taiwan NCT04054817 | ACRO Biomedical Co. Ltd | N/A |
| Completed | Wharton's Jelly Eye Drops in the Treatment of Chronic Keratitis NCT05200000 | TBF Genie Tissulaire | Phase 1 |
| Unknown | Keratoconus, Corneal Diseases and Transplant Registry NCT04164407 | University Hospital, Montpellier | — |
| Unknown | Multiplex Strip Polymerase Chain Reaction for Diagnosis of Eye Infection Diseases From Corneal Scraping Sample NCT04075669 | Fakultas Kedokteran Universitas Indonesia | — |
| Completed | Topical Insulin - Utility and Results in Neurotrophic Keratopathy in Stages 2 and 3 NCT04820010 | Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E. | — |
| Completed | Treatment of Patients With Inflammatory-dystrophic Diseases of the Cornea Using Autologous Stem Cells NCT04484402 | Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | Phase 1 / Phase 2 |
| Completed | Mycotic Antimicrobial Localized Injection for Treatment of Corneal Ulcers NCT02731638 | University of California, San Francisco | Phase 3 |
| Unknown | Topical Anesthesia for Closed PKP vs Retrobulbar Anesthesia for Open-sky PKP NCT02826174 | Wenzhou Medical University | N/A |
| Completed | Cross-linking for Corneal Ulcers Treatment Trial NCT02570321 | University of California, San Francisco | Phase 3 |
| Completed | Fusarium Keratitits in Spain 2012 to 2014 NCT02984904 | Miguel Armando Mosquera Gordillo, MD | — |
| Unknown | Corneal Ulcer Prevention Through Health Education NCT02284698 | Aravind Eye Care System | — |
| Active Not Recruiting | Village Integrated Eye Workers Trial NCT01969786 | University of California, San Francisco | N/A |
| Completed | Corneal Lesions in Intensive Care Unit (ICU) Clinical Trial for Proposing Interventions and Evaluating Outcome NCT02293876 | Hospital Risoleta Tolentino Neves | N/A |
| Completed | Safety and Effectiveness of Collagen-phosphorylcholine Bioengineered Cornea in Patients Requiring Lamellar Ker NCT02277054 | The Filatov Institute of Eye Diseases and Tissue Therapy | N/A |
| Completed | Efficacy and Safety Assessment of T4020 Versus Vehicule in Patients With Chronic Neurotrophic Keratitis or Cor NCT01794312 | Laboratoires Thea | Phase 3 |
| Completed | Evaluation of Safety and Efficacy of rhNGF in Patients With Stage 2 and 3 Neurotrophic Keratitis. NCT01756456 | Dompé Farmaceutici S.p.A | Phase 1 / Phase 2 |
| Unknown | The Asia Cornea Society Infectious Keratitis Study NCT01560208 | Asia Cornea Society | — |
| Completed | The Mycotic Ulcer Treatment Trial II: A Randomized Trial Comparing Oral Voriconazole vs Placebo NCT00997035 | University of California, San Francisco | Phase 3 |
| Completed | Randomized Double Blinded Study Evaluating CACICOL20 Efficiency Versus Placebo Corneal Chronic Ulcers Healing NCT01242839 | Organ, Tissue, Regeneration, Repair and Replacement | N/A |
| Withdrawn | Studying the Relationship Between Contact Lens Packaging Solutions and Bacterial Binding to Surface Eye Cells NCT01104961 | University of Texas Southwestern Medical Center | N/A |
| Unknown | Transplantation of Acellular Corneal Matrix to Treat Corneal Ulcer NCT01244776 | Shaanxi Aierfu Activtissue Engineering | N/A |
| Completed | Mycotic Ulcer Treatment Trial I NCT00996736 | University of California, San Francisco | Phase 3 |
| Terminated | Painless Subconjunctival Antibiotic and Antifungal Injection in Corneal Ulcer Patients NCT00789646 | Mahidol University | N/A |
| Completed | Steroids for Corneal Ulcers Trial NCT00324168 | Thomas M. Lietman | Phase 4 |
| Withdrawn | The Application of Fibrin Glue in Ocular Surface Diseases NCT00155402 | National Taiwan University Hospital | Phase 1 |
| Completed | A Clinical Trial of Povidone-Iodine for the Treatment of Bacterial Corneal Ulcers NCT00386958 | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Phase 2 |