NCT02293876

Corneal Lesions in Intensive Care Unit (ICU) Clinical Trial for Proposing Interventions and Evaluating Outcomes of Nursing in the Adult Intensive Care Center Clinical Trial for Proposing Interventions and Evaluating Outcomes of Nursing in the Adult Intensive Care Center

Risk for Corneal Injury in Critically Ill Patients and Effect of Nursing Interventions for Its Prevention: Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 360 (actual)
• Sponsor: Hospital Risoleta Tolentino Neves · Academic / Other
• Sex: All
• Age: 18 Years – 93 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is find out the better measure to achieve corneal protection in an Intensive Care Unit.

Detailed description

Critically ill patients are at higher risk for corneal injury and the mechanisms responsible for ocular lubrication and protection can be compromised. However, the literature diverges on which is the best clinical practice for treatment. There is a scale for assessing the risk for corneal injury. Thus, the general objective of this study was to evaluate the risk for developing corneal injury in critically ill patients and the effectiveness of three types of interventions: eye gel, eyedrops and polyethylene film, compared to the control group in its prevention. The specific objectives were: verify the most effective intervention for the prevention of corneal injury from the available literature and provided by: eye gel, eyedrops and polyethylene film compared to the control group who received eye care through randomized controlled clinical trial. Patients and methods: This study was a randomized controlled trial to determine the best care for the prevention of corneal injury from those available on the market (eye drops, eye gel and polyethylene film), compared to a control group (eye care) in the period from 09/07/2013 to 03/15/2014 .

Conditions

• Keratitis
• Corneal Ulcer

Interventions

Type	Name	Description
DEVICE	LACRIBELL®	Hypromellose and dextran based eyedrop, used in the treatment of dry eye.
DEVICE	LIPOSIC®	Carbomer and Sorbitol based gel, used in the treatment of dry eye.
DEVICE	Glad wrap	A clear plastic wrap occluding eye and orbital area, turning the space into a moisture chamber.

Timeline

• Start date: 2013-04-01
• Primary completion: 2014-04-01
• Completion: 2014-11-01
• First posted: 2014-11-18
• Last updated: 2014-11-19

Locations

1 site across 1 country: Brazil