| Not Yet Recruiting | Natrunix in HLA-B27 Positive Subjects With Axial Spondyloarthritis NCT06526377 | XBiotech, Inc. | Phase 2 |
| Recruiting | Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic D NCT07087912 | University of Sao Paulo General Hospital | Phase 4 |
| Recruiting | A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over T NCT07290036 | UCB Biopharma SRL | Phase 1 |
| Recruiting | A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With NCT06888193 | UCB Biopharma SRL | Phase 1 |
| Active Not Recruiting | Walking Football for Axial Spondyloarthritis NCT07414823 | Portsmouth Hospitals NHS Trust | N/A |
| Not Yet Recruiting | Exploring the Feasibility and Acceptability of Virtual Reality Exercise for Pain Management, Fear of Movement, NCT06967077 | University of Bath | N/A |
| Not Yet Recruiting | Efficacy of Non-invasive Vagus Nerve Stimulation for Axial Spondyloarthritis Resistant to Biotherapies NCT04286373 | Assistance Publique - Hôpitaux de Paris | N/A |
| Recruiting | A Study of SPY072 in Rheumatic Disease NCT07148414 | Spyre Therapeutics, Inc. | Phase 2 |
| Not Yet Recruiting | Assessing the Feasibility of the Patient-Reported Outcomes Based Model for Community Care of Patients With Axi NCT06968247 | Singapore General Hospital | N/A |
| Recruiting | The Disease Progression of Chinese Axial Spondyloarthritis in a Real-word Cohort Study NCT06844643 | China-Japan Friendship Hospital | — |
| Recruiting | Taekwondo for Axial Spondyloarthritis NCT06823726 | Wonju Severance Christian Hospital | N/A |
| Completed | Ultrasonographic Evaluation of the Shoulder Joint in Patients With Axial Spondyloarthritis NCT06727266 | Gaziosmanpasa Research and Education Hospital | — |
| Recruiting | INSELMA - a Randomised Controlled Trial NCT06583980 | The Danish Center for Expertise in Rheumatology | N/A |
| Not Yet Recruiting | Barriers and Faciliators for Physical Activity in People With RMDs NCT06514443 | Anne-Kathrin Rausch | — |
| Not Yet Recruiting | Efficacy and Safety of SCT650C in Participants With Axial Spondyloarthritis NCT06197009 | Sinocelltech Ltd. | Phase 2 |
| Recruiting | Fecal Microbiota Transplantation in Axial Spondyloarthritis NCT06451588 | University Hospital of North Norway | Phase 2 |
| Enrolling By Invitation | Spondyloarthritis Inception Cohort of Southern Denmark NCT06337513 | The Danish Center for Expertise in Rheumatology | N/A |
| Recruiting | axSEND: Exploring Immune and Microbiota Effects of a Partial Enteral Nutrition Diet in Axial Spondyloarthritis NCT06460805 | NHS Greater Glasgow and Clyde | N/A |
| Recruiting | A LONGITUDINAL OBSERVATIONAL STUDY to EVALUATE the EFFICACY of MOVEMENT and IMPLEMENT CONCRETE MOVEMENT RECOMM NCT06807853 | University of Bonn | — |
| Recruiting | The Efficacy of Fecal Microbiota Transplatation on Axial Spondyloarthritis Patients Resistant to Conventional NCT05654753 | Assistance Publique - Hôpitaux de Paris | Phase 2 / Phase 3 |
| Recruiting | A Study to Evaluate 608 in Patients With Non- Radiographic Axial Spondyloarthritis (Nr-axSpA) NCT06222671 | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | Phase 2 |
| Recruiting | WORK-ON Vocational Rehabilitation for People with Inflammatory Arthritis NCT06299917 | The Danish Center for Expertise in Rheumatology | N/A |
| Completed | Reliability of BASDAI and BASFI Applied by Tele-Assessment Method in Axial SpA Spondyloarthritis NCT06230952 | Siirt University | — |
| Active Not Recruiting | Study of the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of BCD-180 in Patients With Axial Spondyl NCT06333210 | Biocad | Phase 3 |
| Completed | Telerehabilitation and Face-to-Face Clinical Pilates-Based Exercise in Individuals With Axial Spondyloarthriti NCT05006690 | Hacettepe University | N/A |
| Recruiting | ToFAcitinib in Early Active Axial SpondyloarThritis: NCT06112665 | Charite University, Berlin, Germany | Phase 4 |
| Recruiting | Optimizing Anti-IL17 Antibody Therapy by Associating Fiber Supplementation to Correct Treatment-aggravated Gut NCT05812157 | Centre Hospitalier Universitaire de Nīmes | N/A |
| Completed | The Impact of Simulated Forest Immersion Therapy on Pain and Anxiety in Patients Axial Spondyloarthritis (axSp NCT06072859 | Oregon Health and Science University | N/A |
| Recruiting | Osteosarcopenia in Axial Spondyloarthritis NCT06577350 | Ankara University | — |
| Completed | Comparison of Tele-rehabilitation or Video-Based Core Exercises in Individuals With Axial Spondyloarthritis NCT06000072 | Acibadem University | N/A |
| Unknown | Characterizing Spondyloarthritis With 68Ga-FAPI PET/CT NCT05999643 | The First Affiliated Hospital of Xiamen University | N/A |
| Completed | New Biomarkers in Axial Sypondyloarthropathy; SII and SIRI NCT05914532 | Istanbul Training and Research Hospital | — |
| Completed | Enthesis Differences in Rheumatoid Arthritis and Axial Spondyloarthropathy NCT05942976 | Istanbul Training and Research Hospital | — |
| Recruiting | British Axial Spondyloarthritis Inception Cohort NCT05676775 | The Leeds Teaching Hospitals NHS Trust | — |
| Active Not Recruiting | A Study Evaluating the Effect of Filgotinib in Participants With Active Axial Spondyloarthritis NCT05785611 | Alfasigma S.p.A. | Phase 3 |
| Completed | RAFTLIN-1 Levels in Axial Spondyloarthritis and Psoriatic Arthritis NCT05771389 | Bezmialem Vakif University | N/A |
| Completed | Comparison of CT Scan Between Patients With Axial Spondyloarthritis and Control Subjects NCT05779969 | Hôpital NOVO | — |
| Unknown | Unmet Needs of Axial Spondyloarthrits in Egyptian Patients NCT05517031 | Sohag University | — |
| Recruiting | Factors for the Onset and Course of Axial Spondylitis NCT06594107 | Karolinska Institutet | — |
| Unknown | Health Technology to Improve Exercise in axSpA NCT05504616 | University Health Network, Toronto | N/A |
| Completed | Study of Efficacy and Safety of GR1501 in Patients with Radiographic Axial Spondyloarthritis NCT05881785 | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | Phase 3 |
| Active Not Recruiting | Study of the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of BCD-180 in Patients With Axial Spondyl NCT05445076 | Biocad | Phase 2 |
| Recruiting | High-intensity Training in Patients With Spondyloarthritis: a Randomized Controlled Trial NCT05781763 | Halmstad University | N/A |
| Unknown | Video Coaching of Physical Activity in Axial Spondyloarthritis NCT03965650 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Biomedicines and Bacterial Translocation in Spondyloarthritis NCT05244109 | Centre Hospitalier Universitaire de Besancon | N/A |
| Unknown | REduCed Dose of TNFi in Patients With Ankylosing SpondyliTis (RECAST) NCT05164198 | Hanyang University Seoul Hospital | Phase 4 |
| Completed | Tofacitinib in the Treatment of Refractory Axial Spondyloarthritis Patients: A Dose Escalation Study NCT06310057 | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Phase 4 |
| Unknown | Biologic Tapering Study of TNF Inhibitors in Axial Spondyloarthritis NCT05115903 | University Health Network, Toronto | Phase 4 |
| Completed | Physiotherapy of Axial Spondyloarthritis NCT04679649 | Royal United Hospitals Bath NHS Foundation Trust | N/A |
| Completed | Exercise Therapy in Patients With Axial Spondyloarthritis NCT04368494 | Loughborough University | N/A |
| Completed | Remote Monitoring of Axial Spondyloarthritis NCT05031767 | Diakonhjemmet Hospital | N/A |
| Completed | The Turkish Version of the Inflammatory Arthritis Facilitators and Barriers to Physical Activity NCT05019547 | Acibadem University | — |
| Completed | Reliability of IBP Criteria & Activity Scores in Patients With AxSpA NCT05327140 | Zagazig University | — |
| Completed | Prevelance of Frailty and Its Associated Factors in Patients With Axial Spondyloarthritis NCT05010720 | Acibadem University | — |
| Unknown | Explore the Associations of Behavioral Factors With Treatment Adherence in Axial Spondyloarthritis Patients Tr NCT04925037 | University Hospital, Clermont-Ferrand | — |
| Completed | Secukinumab (Cosentyx®) Effectiveness in Axial Spondyloarthritis and Psoriatic Arthritis Patients Using Artifi NCT05677542 | Novartis Pharmaceuticals | — |
| Withdrawn | Terbinafine Treatment of Axial Spondyloarthropathy NCT05119712 | Oregon Health and Science University | EARLY_Phase 1 |
| Unknown | Clinical Trial of Electroacupuncture in Axial Spondyloarthritis (E-AcuSpA) NCT04519866 | Singapore General Hospital | N/A |
| Completed | The Relationship Between Magnetic Resonance Imaging (MRI) Scores and Sensory Testing in Axial Spondyloarthriti NCT05021783 | Marmara University | — |
| Active Not Recruiting | The Relationship Between Inflammatory ARTritis and CArdiac DIseAse NCT05647577 | University Hospital, Gentofte, Copenhagen | — |
| Completed | to Evaluate the Preliminary Efficacy and Safety of GR1501 Injection in Patients With Active Axial Spondyloarth NCT05162937 | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | Phase 2 |
| Unknown | The Role of Microbiome on Biological Therapy Efficacy in axSpA and RA NCT04973787 | Universidade Nova de Lisboa | — |
| Terminated | Individualizing Anti-Inflammatory Medications for Adults With Axial Spondyloarthritis: A Series of N-of 1 Tria NCT04115098 | The University of Texas Health Science Center, Houston | Phase 2 |
| Terminated | Microbiome and Axial Spondyloarthritis NCT04713995 | Viome | N/A |
| Completed | A Study in Pregnant Women With Chronic Inflammatory Diseases Treated With Cimzia (Certolizumab Pegol) NCT04163016 | UCB Biopharma SRL | Phase 1 |
| Active Not Recruiting | A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Subjects With Active Axi NCT04436640 | UCB Biopharma SRL | Phase 3 |
| Unknown | Prevalence and Seroconversion of COVID-19 in Autoimmune Diseases in Europe NCT04397237 | Pitié-Salpêtrière Hospital | — |
| Terminated | COVID-19 Infection in Vulnerable Patients With Inflammatory Rheumatic Diseases NCT04335747 | Salome Kristensen | — |
| Completed | French Validation of Axial Spondyloarthritis Questionnaires (Val-SpA) NCT04212806 | University Hospital, Grenoble | — |
| Unknown | Effectiveness of Interdisciplinary Care Compared to Usual Care in Patients With Immune-Mediated Inflammatory D NCT04200690 | University of Aarhus | N/A |
| Completed | Investigation of Central Sensitization Frequency and Related Factors in Axial Spondyloarthritis Patients NCT04485078 | Marmara University | — |
| Recruiting | Advanced Sensor Based Functional ASsessmenTs in Axial Spondyloarthritis NCT04489342 | Western Health and Social Care Trust | — |
| Completed | AScalate: Treat-to-target in Axial Spondyloarthritis NCT03906136 | Novartis Pharmaceuticals | Phase 3 |
| Completed | PROM Collected Via a Smartphone App Versus a Touch Screen Solution Among Patients With Inflammatory Arthritis NCT03486613 | Salome Kristensen | N/A |
| Completed | MRE as a Screening Tool for axSpA in IBD NCT03817983 | Cambridge University Hospitals NHS Foundation Trust | — |
| Unknown | Treat-to-target With Secukinumab in Axial Spondyloarthritis NCT03639740 | Professor Mikkel Østergaard | Phase 4 |
| Completed | Rheumatism and Dietetic: RHUMADIET Study (Food Practices and Beliefs) NCT03770884 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Rotation or Change of Biotherapy After TNF Blocker Treatment Failure for Axial Spondyloarthritis NCT03445845 | Centre Hospitalier Universitaire de Saint Etienne | Phase 4 |
| Completed | Efficacy and Safety of Namilumab for Moderate-to-severe Axial Spondyloarthritis NCT03622658 | Izana Bioscience Ltd. | Phase 2 |
| Completed | Safety, Tolerability and PK of SHR1314 in axSpA NCT03704428 | Jiangsu HengRui Medicine Co., Ltd. | Phase 1 |
| Active Not Recruiting | Clinical Trial of TCM Collaborative Care Model in Axial Spondyloarthritis NCT03420404 | Singapore General Hospital | N/A |
| Terminated | Non-Steroidal Anti-inflammatory Drugs in Axial Spondyloarthritis NCT03473665 | Columbia University | Phase 4 |
| Recruiting | Effects of Nonsteroidal Anti-Inflammatory Drugs in Recurrence of Spondyloarthritis Patients After Remission NCT03425812 | The First Affiliated Hospital of Xiamen University | N/A |
| Terminated | A Post-Marketing-Observational Study (PMOS) to Determine the Effectiveness of Combined Adalimumab Treatment an NCT03258814 | AbbVie | — |
| Completed | Efficacy of Golimumab in Early Axial Spondyloarthritis in Relation to Gut Inflammation NCT03270501 | University Ghent | Phase 3 |
| Completed | Lessening the Impact of Fatigue in Inflammatory Rheumatic Diseases NCT03248518 | University of Aberdeen | N/A |
| Unknown | Safety and Efficacy of Tofacitinib in the Treatment of NSAID Refractory Axial Spondyloarthritis:A Clinical Tri NCT03738956 | Globe Pharmaceuticals Limited | Phase 2 / Phase 3 |
| Completed | Observational Study to Evaluate the Real-Life Effectiveness of Benepali Following Transition From Enbrel NCT03100734 | Biogen | — |
| Completed | A Clinimetric Test of Spinal Sensors in Measuring Spinal Mobility in Axial Spondyloarthritis NCT03159767 | Dr Philip Gardiner | N/A |
| Completed | A Long Term Extension Study of Ixekizumab (LY2439821) in Participants With Axial Spondyloarthritis NCT03129100 | Eli Lilly and Company | Phase 3 |
| Completed | A Study of Brodalumab in Subjects With Axial Spondyloarthritis (axSpA) NCT02985983 | Kyowa Kirin Co., Ltd. | Phase 3 |
| Completed | Analysis of DNA Methylation in Spondyloarthritis NCT03092583 | Centre Hospitalier Universitaire de Besancon | N/A |
| Completed | Treat to Target Trial in Axial Spondylo Arthritis : The TICOSPA (Tight Control in Spondyloarthritis) NCT03043846 | Association de Recherche Clinique en Rhumatologie | — |
| Unknown | Is the Human Microbiome Altered in Patients With Axial Spondyloarthritis? NCT02962479 | Eyal Kedar | — |
| Terminated | A Study Treating Participants With Early Axial Spondyloarthritis (axSpA) Taking an Intense Treatment Approach NCT02897115 | AbbVie | Phase 4 |
| Completed | Study of Efficacy and Safety of Secukinumab in Psoriatic Arthritis and Axial Spondyloarthritis Patients With A NCT02771210 | Novartis Pharmaceuticals | Phase 3 |
| Completed | A Study of Ixekizumab (LY2439821) in Participants With Nonradiographic Axial Spondyloarthritis NCT02757352 | Eli Lilly and Company | Phase 3 |
| Completed | Patient Reported Outcomes Reported Via PC / Tablet Home Versus Touch Screen at Hospital Among Patients With Ar NCT02818478 | Henrik Gudbergsen | N/A |
| Completed | Add-on Therapy for Axial Spondyloarthritis NCT02744014 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Completed | Serum Creatinine Change / Renal Adverse Effect With Use of Non-steroidal Painkillers in Axial Spondyloarthriti NCT03582332 | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Phase 4 |
| Completed | Incidence of MRI Sacro-Iliac Joint Anomalies in Young Women NCT02956824 | University Hospital, Montpellier | N/A |
| Terminated | A Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Anti-TNFα Naive Participants Wi NCT02437162 | Janssen Research & Development, LLC | Phase 3 |
| Completed | Multicenter Study Evaluating Certolizumab Pegol Compared to Placebo in Subjects With axSpA Without X-ray Evide NCT02552212 | UCB BIOSCIENCES GmbH | Phase 3 |
| Completed | The Effect of Exercise on Disease Activity and Cardiovascular Risk for Patients With Axial SpondyloArthritis NCT02356874 | Diakonhjemmet Hospital | N/A |
| Terminated | A Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Anti-TNF(Alpha) Refractory Part NCT02438787 | Janssen Research & Development, LLC | Phase 3 |
| Withdrawn | Study of Efficacy and Safety of Brodalumab Compared With Placebo in Subjects With Axial Spondyloarthritis NCT02429882 | Amgen | Phase 2 |
| Unknown | Identification of New Biomarkers to Promote Personalized Treatment of Patients With Inflammatory Rheumatic Dis NCT03214263 | Rigshospitalet, Denmark | — |
| Unknown | PatientSpot Formerly Known as ArthritisPower NCT03840928 | Global Healthy Living Foundation | — |
| Completed | A Study To Evaluate The Efficacy Of Enbrel (REGISTERED) Etanercept Over A Period Of 12 Months In The Routine T NCT02486302 | Pfizer | — |
| Completed | COMorbidities and EDucation in SPondyloArthritis Study NCT02374749 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | A Study to Assess the Effectiveness of Certolizumab Pegol in Patients With Axial Spondyloarthritis in Daily Li NCT02354105 | UCB Biopharma S.P.R.L. | — |
| Completed | PREDICT-SpA - French Epidemiological Study of the Evaluation of the Impact of Fibromyalgia in the TNF Alpha Tr NCT03039088 | Association de Recherche Clinique en Rhumatologie | — |
| Unknown | Does Immunogenicity Have an Influence on the Efficacy of Anti-TNF Therapy in Patients With AS: An Inception Co NCT02687620 | Izmir Katip Celebi University | — |
| Unknown | The IMPACT of a Referral Model for Axial Spondyloarthritis in Young Patients With Chronic Low Back Pain NCT01944163 | Maasstad Hospital | N/A |
| Completed | Exercise Capacity, Cardiovascular Risk Factors and Disease-related Variables in Axial Spondyloarthritis NCT04706650 | Muğla Sıtkı Koçman University | — |
| Completed | Treatment of Axial Spondyloarthritis With Reduced Doses of NSAIDs NCT02089529 | University Hospital of North Norway | N/A |
| Completed | Continuing Versus Withdrawing Adalimumab in Maintaining Remission in Non-Radiographic Axial Spondyloarthritis NCT01808118 | AbbVie | Phase 3 |
| Completed | Novel MRI ANd Biomarkers in GOlimumab-treated Patients With Axial Spondyloarthritis NCT02011386 | Professor Mikkel Østergaard | — |
| Completed | A Study to Evaluate the NSAIDS Sparing Effect of Etanercept in Subjects With Axial Spondyloarthritis NCT01298531 | Pfizer | Phase 4 |
| Completed | Infliximab for Treatment of Axial Spondyloarthritis (P05336 AM1) NCT00844805 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | Study of Adalimumab in Patients With Axial Spondyloarthritis NCT00939003 | AbbVie (prior sponsor, Abbott) | Phase 3 |
| Completed | Diagnostic Criteria in the Diagnosis of Spinal Spondyloarthropathies in Patients With Chronic Low Back Pain (S NCT00726765 | Merck Sharp & Dohme LLC | — |