NCT06844643

The Disease Progression of Chinese Axial Spondyloarthritis in a Real-word Cohort Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 2,250 (estimated)
• Sponsor: China-Japan Friendship Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

An observational, ambispective cohort to learn about the disease progression of axial spondyloarthritis (axSpA) according to the changes from baseline in measures of disease activity, function, and imaging.

Detailed description

This is an observational cohort study of Chinese patients (≥18 years of age) diagnosed with axSpA. Patients are followed at 4-6 month intervals. Data will be collected at baseline and at every follow-up time points. Primary outcomes are the structural damage measured with imaging(Conventional radiography, low-dose CT and MRI) and the disease activity measured with the Ankylosing Spondylitis Disease Activity Scale (ASDAS) and the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). Secondary outcomes are inflammatory markers, Bath ankylosing spondylitis functional index (BASFI) and Bath ankylosing spondylitis metrology index (BASMI).

Conditions

• Axial Spondyloarthritis
• Ankylosing Spondylitis (AS)

Timeline

• Start date: 2025-03-01
• Primary completion: 2030-12-01
• Completion: 2030-12-01
• First posted: 2025-02-25
• Last updated: 2026-04-13

Locations

1 site across 1 country: China