| Not Yet Recruiting | Postoperative Oral Tranexamic Acid in Patients Undergoing Primary Total Joint Arthroplasty NCT06832878 | Mayo Clinic | Phase 4 |
| Not Yet Recruiting | Muscle Damage of the TFL (Tensor Fascia Latae) During Total Hip Arthroplasty (THA) Through Direct Anterior App NCT07360210 | University Hospital, Bordeaux | N/A |
| Recruiting | Cryoneurolysis Prior to Total Knee Arthroplasty (CRYO-TKA Trial) NCT07425457 | Attikon Hospital | N/A |
| Active Not Recruiting | Phenol Neurolysis and Radiofrequency Thermocoagulation in Knee Arthroplasty Surgery NCT07381335 | Aydin Adnan Menderes University | N/A |
| Enrolling By Invitation | Effect of Preoperative Pain Education on Anxiety, Pain, and Analgesic Use in Total Knee and Hip Replacement Pa NCT07362589 | Yeditepe University | N/A |
| Recruiting | INHANCE Stemless Reverse Shoulder IDE NCT06323980 | DePuy Orthopaedics | N/A |
| Withdrawn | Robotic Assisted Knee Arthroplasty - Retain the Anterior Cruciate Ligament or Not NCT06264999 | St. Olavs Hospital | N/A |
| Not Yet Recruiting | The Effect of Progressive Relaxation Exercises on Postoperative Pain NCT05971641 | Bartın Unıversity | N/A |
| Recruiting | PRIMA EU Retrospective & Prospective NCT06371833 | Limacorporate S.p.a | — |
| Not Yet Recruiting | A Randomized Controlled Trial of the Sagittal Alignment Difference Between Mako Robotic TKA and Manual TKA NCT06527911 | Chinese PLA General Hospital | — |
| Not Yet Recruiting | Post Surgical Multimodal Analgesia With Oral Strong Opioids NCT06554457 | Tri-Service General Hospital | — |
| Unknown | Xarelto for Thromboprophylaxis After Total Hip and Total Knee Arthroplasty NCT05449327 | Chiayi Christian Hospital | N/A |
| Completed | H-35 CL TRAUMA Cemented Femoral Stem NCT05606120 | Limacorporate S.p.a | — |
| Withdrawn | Evaluate the Performance of JOURNEY II CR and JOURNEY II BCS in TKA Populations NCT04822259 | Smith & Nephew, Inc. | N/A |
| Completed | Risk Factors for Acute Kidney Injury in Patients Undergoing Arthroplasty NCT06296108 | Ankara University | — |
| Completed | Mobilization Protocol for Knee Arthroplasty Patients NCT05679947 | Gazi University | N/A |
| Terminated | Difference in Patellar Tracking Before and After Journey II BCS Total Knee Arthroplasty, Evaluated With 4D CT NCT05824533 | Sebastiaan van de Groes | N/A |
| Not Yet Recruiting | S-11 SMR TT Hybrid Glenoid and Cementless Finned Short Stem NCT05314387 | Limacorporate S.p.a | — |
| Terminated | Evaluate the Performance of JOURNEY II CR in TKA Populations NCT04818840 | Smith & Nephew, Inc. | — |
| Recruiting | Study to Evaluate the Safety and Effectiveness of the REAL INTELLIGENCE™ CORI™ in Total Knee Arthroplasty (TKA NCT04848896 | Smith & Nephew, Inc. | N/A |
| Active Not Recruiting | To Evaluate the Performance of the CORI™ KNEE TENSIONER as an Accessory to the CORI™ Surgical System. NCT04849884 | Smith & Nephew, Inc. | N/A |
| Completed | TKA Melatonin and Sleep Quality NCT05332717 | Hospital for Special Surgery, New York | N/A |
| Active Not Recruiting | Healthy Living After Knee Replacement NCT05190666 | University of South Carolina | N/A |
| Completed | Evaluation of the Clinical and Radiological Outcome of Uncemented Femoral Stems According to Their Proximal Co NCT05015101 | GCS Ramsay Santé pour l'Enseignement et la Recherche | — |
| Unknown | Implementation of a Rehabilitation Technology in Orthopedic and Neurological Rehabilitation to Increase Therap NCT04906681 | PXL University College | Phase 1 / Phase 2 |
| Unknown | Walking Stick Exercise in Patients Underwent Total Knee Arthroplasty NCT05030662 | National Taipei University of Nursing and Health Sciences | N/A |
| Completed | Transfusion Rates in Total Hip Replacement Before/After the Implementation of a Patient Blood Management Progr NCT04398238 | Istituto Ortopedico Rizzoli | — |
| Recruiting | ORIGIN® vs. VANGUARD® PS Observational Study NCT04728542 | Symbios Orthopedie SA | — |
| Completed | Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Knee Arthroplasty Procedures NCT04786119 | Smith & Nephew, Inc. | N/A |
| Terminated | Triathlon PSR Outcomes Study NCT04618770 | Stryker Orthopaedics | N/A |
| Terminated | Rehabilitation with Personalized Strategies According to Muscle Volume Before Knee Arthroplasty NCT04318197 | University Hospital, Brest | N/A |
| Recruiting | Arthroplasty Cements Outcomes - A Post-market Follow-up NCT06354543 | Teknimed | — |
| Unknown | Sonography-guided Pericapsular Never Group Block for Hip Arthroplasty NCT04480320 | Guangzhou First People's Hospital | N/A |
| Completed | Knotless Suture in Revision Total Joint Arthroplasty NCT04403919 | NYU Langone Health | N/A |
| Completed | Knee Connect: Physiotherapy Exercise Performance With Visual Feedback After Total Knee Arthroplasty NCT03738384 | Sunnybrook Health Sciences Centre | N/A |
| Completed | Pain After Preoperative UltraSound Guided Hip Injections for Total Hip Arthroplasty (PUSH) NCT04219098 | Anne Arundel Health System Research Institute | N/A |
| Completed | Effects of Sensorimotor and Core Stabilization Exercises After Total Knee Arthroplasty NCT05248854 | Yeditepe University | N/A |
| Completed | Length of the Femoral Stem in Arthroplasty Done for Patients With Proximal Femoral Metastatic Lesion NCT04660591 | Ain Shams University | N/A |
| Terminated | A Post-Market Clinical Evaluation of the ReUnion Reversible Fracture (RFX) System NCT04089371 | Stryker Trauma and Extremities | — |
| Completed | Mineral Nano Pathology NCT03898531 | Hospices Civils de Lyon | — |
| Completed | Influence of the Operative Day on the Average Duration of Stay in Primary Hip and Knee Replacements NCT03132831 | Centre Hospitalier Universitaire, Amiens | — |
| Completed | Survey of Running Following a TKA NCT03848520 | Brigitte Jolles, MD | — |
| Unknown | Home Rehabilitation Using Interactive Device Versus Inpatient Rehabilitation in Total Knee Arthroplasty NCT03476148 | The Catholic University of Korea | N/A |
| Completed | Effects of Early Home-based Strength and Sensory-motor Training After THA on Functional Outcome and Patient Sa NCT04061993 | Valdoltra Orthopedic Hospital | N/A |
| Completed | CapFlex-PIP© Motion NCT02425319 | Schulthess Klinik | — |
| Completed | The Effects of Prehabilitative Exercise on Functional Recovery Following Total Knee Arthroplasty NCT03227120 | Carilion Clinic | N/A |
| Completed | Multiple Electrode Aggregometry to Assess Platelet Function in Patients Undergoing Hip Joint Alloplasty With a NCT03121378 | Medical University of Warsaw | — |
| Completed | Long-term Evaluation Protocol (12 Months Postoperative) of Total Knee Prostheses Anatomic With Resurfaced Pate NCT03081260 | Hospices Civils de Lyon | N/A |
| Completed | An Attempt to Find Out Root Cause of a Pain Producing Knee Disease NCT04496440 | DR R C Agrawal | — |
| Completed | Efficacy of Preoperative Muscle Training on Postoperative Orthopaedic Surgery Recovery NCT03483519 | Ottawa Hospital Research Institute | N/A |
| Unknown | Effect of Tourniquet on UKA NCT02465684 | Medical University Innsbruck | N/A |
| Completed | Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip Arthroplasty NCT02658149 | Corewell Health East | Phase 4 |
| Completed | Anterior Minimal Invasive Surgery Versus Antero-lateral Approach in Hip Joint Hemiarthroplasty NCT05255198 | Rehabilitation Hospital Tobelbad | — |
| Unknown | The Influence of Rapid Recovery on Sleep Quality Following Total Hip Replacement Surgery NCT02852460 | Southwest Hospital, China | N/A |
| Withdrawn | Comparison of Comparison of Ropivacaine and Liposomal Bupivacaine for Total Knee Arthroplasty NCT02616367 | University of Minnesota | Phase 2 |
| Active Not Recruiting | Uncemented Tritanium Compared With Cemented Metal-backed Tibia Components in Total Knee Replacement NCT02578446 | Region Skane | N/A |
| Completed | Radiological Measurement of Femoral Stem Version Using Lateral Decubitus Method: A Prospective Study NCT02554149 | Seoul National University Bundang Hospital | — |
| Terminated | Materialise X-ray Knee Guides for Total Knee Arthroplasty NCT02713906 | Materialise | N/A |
| Unknown | Comparison of Three Knee Replacements NCT03339557 | Coxa, Hospital for Joint Replacement | N/A |
| Active Not Recruiting | Triathlon Tritanium Cone Augments Outcomes Study NCT02521103 | Stryker Orthopaedics | N/A |
| Unknown | Translation, Cross Cultural Adaptation and Validation of the Italian Version of the Forgotten Joint Score in T NCT03805490 | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | — |
| Completed | Pre-operative One-on-One Physical Therapy Education Improves Postoperative Function and Patient Satisfaction A NCT02872337 | Hospital for Special Surgery, New York | N/A |
| Completed | Continuous Adductor Canal Block (CACB) vs. Combined Spinal Epidural (CSE) in Total Knee Arthroplasty NCT02415465 | Rush University Medical Center | N/A |
| Unknown | The Efficacy and Optimal Dose of Sufentanil in Patient Controlled Analgesia After Moderate Surgery NCT02503826 | Second Affiliated Hospital of Xi'an Jiaotong University | Phase 4 |
| Completed | Effectiveness of Pulsed Radiofrequency of the Saphenous Nerve in the Management of Knee Arthroplasty Pain NCT03450681 | Fundación Santa Fe de Bogota | N/A |
| Unknown | Understanding GMK Sphere Implant Tibiofemoral Kinematics by Means of Dynamic Videofluoroscopy NCT02828293 | Medacta International SA | — |
| Completed | Does the Measurement of Pupillary Reactivity by an Automated Pupillometer Determine the Effectiveness of Local NCT01685645 | Centre Hospitalier Universitaire de Nīmes | N/A |
| Completed | Total Hip Arthroplasty Outcomes With Regional and Multimodal Analgesia NCT02186795 | Medical University of South Carolina | — |
| Terminated | Silicone Arthroplasty vs. Arthrodesis in the Distal Interphalangeal Joint NCT01740999 | Schulthess Klinik | N/A |
| Unknown | Predictive Model for Postoperative Complications in Hemi-hip Arthroplasty NCT03375268 | Seoul National University Hospital | — |
| Completed | Preoperative Pain, Function, and Activity for Total Hip and Knee Arthroplasty Patients NCT01248039 | Hvidovre University Hospital | — |
| Completed | AMIStem-H Radiographic Analysis NCT02829866 | Medacta International SA | — |
| Completed | Dilute Betadine Lavage in the Prevention of Postoperative Infection NCT01175044 | Rush University Medical Center | Phase 4 |
| Completed | Comparison of Pain Relief After Non Stimulating Interscalene Catheter Placement vs Stimulating Catheter Placem NCT01122732 | University of Chicago | — |
| Completed | Effect of Prophylactic Antibiotics on Intra-Operative Culture Results NCT01174212 | Rush University Medical Center | Phase 4 |
| Terminated | Knee Joint Icing and Knee-extension Strength NCT01249612 | Hvidovre University Hospital | Phase 1 |
| Completed | Cardiovascular Changes and Changes in Tissue Oxygenation During Early Postoperative Mobilization in Total Hip NCT01089946 | Rigshospitalet, Denmark | — |
| Completed | Establishment of Optimal Transfusion Threshold After Major Orthopedic Surgery NCT00906295 | Rigshospitalet, Denmark | N/A |
| Completed | The Effect of Patellar Eversion on Functional Outcomes in Primary Total Knee Arthroplasty NCT01777009 | Northwell Health | N/A |
| Unknown | Stability Plus - Outcomes From Extended Continuum of Care NCT00756483 | Stability Plus, LLC | — |
| Completed | The Effect of the Combined Use of Naloxone and Tramacet on Postoperative Analgesia in the Elderly NCT00665262 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Phase 4 |
| Not Yet Recruiting | Effect of Local Pamidronate in Preventing Bone Loss After Total Hip Arthroplasty NCT00548288 | General and Teaching Hospital Celje | Phase 1 |
| Unknown | Mobility Assessment of Patients With Total Hip Arthroplasty NCT00664508 | Ottawa Hospital Research Institute | N/A |
| Terminated | Efficacy and Safety Study of 4975 in Patients Undergoing Total Hip Replacement NCT00683267 | Anesiva, Inc. | Phase 2 |
| Recruiting | Heidelberg Registry for Hip and Knee Joint Implants and Revisions NCT06850818 | University Hospital Heidelberg | — |
| Terminated | A Study to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) in the Treatment of Acute Pain After Hi NCT00364533 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Phase 3 |
| Completed | RCT Comparing Ion Levels and Clinical Outcomes of A-Class BFH to Metal on Polyethylene Total Hip Replacement NCT00911599 | Ottawa Hospital Research Institute | N/A |
| Completed | Total Temporomandibular Joint Replacement System Post Approval Study NCT00762944 | Zimmer Biomet | — |
| Completed | Comparison of Metal on Metal Total Hip Arthroplasty and Metal on Metal Total Hip Resurfacing. NCT04516239 | Ciusss de L'Est de l'Île de Montréal | Phase 4 |
| Completed | ThromboEmbolism Prevention Efficacy and Safety Trial (TEMPEST) NCT00041509 | GlaxoSmithKline | Phase 2 |