NCT05190666

Healthy Living After Knee Replacement

Physical Activity and Weight Loss to Improve Function and Pain After Total Knee Replacement

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 182 (actual)
• Sponsor: University of South Carolina · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

The purpose of this study is to examine if a weight loss program designed for adults after knee replacement improves weight loss, physical activity, pain, and function, as well as if the program is cost effective, as compared to a chronic disease self-management program.

Detailed description

Participants will be randomized to either a weight loss program or chronic disease self-management program. Both programs will be phone-based and include phone calls with a health coach weekly during months 1-4, biweekly during months 5-6, and monthly during months 7-12. Monthly calls with occur between months 13-18. Assessments examining outcomes will be completed at baseline, 6, 12, and 18 months.

Conditions

• Arthroplasty
• Overweight and Obesity

Interventions

Type	Name	Description
BEHAVIORAL	PACE Weight Loss program	12 month phone-based behavioral weight loss program
BEHAVIORAL	Chronic Disease Self-Management	12 month phone-based chronic disease self-management program

Timeline

• Start date: 2022-01-04
• Primary completion: 2026-06-30
• Completion: 2027-07-30
• First posted: 2022-01-13
• Last updated: 2026-04-03

Locations

1 site across 1 country: United States