NCT04496440

An Attempt to Find Out Root Cause of a Pain Producing Knee Disease

Primary Osteoarthritis Knee - Establishing Its Cause, Pathogenesis and Treatment

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 138 (actual)
• Sponsor: DR R C Agrawal · Academic / Other
• Sex: All
• Age: 30 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This study was focused on a type of arthritis (knee) in which patients develop pain with disabilities in sitting and walking etc. In advance stage the person is bereft of his/her personal physical activities. The prevalent treatment is temporary and dis-satisfactory. A new treatment was designed and a trial was conducted on 125 patients (100 in the trial group, 25 in the control group) for a duration of six months.

Detailed description

The study was focused on establishing the cause and treatment of a painful knee joint disease (Primary Osteoarthritis Knee = OA Knee). At present the cause and treatment are not known. The study was based on a hypothesis, designing a treatment and testing it through a clinical trial. This established that the deficient full flexion or deficient full extension of knee joints, producing contracture in their capsules was the cause and the correction (Contracture Correction Therapy = CCT) was the cure of the disease. The correction was carried out by passive flexion or passive extension of affected knee through eight body postures designed specifically during the study. To test the efficacy a multi-centre, multi surgeon six months study on 125 patients was carried out, patients were divided into Trial and Control groups. The effects were measured by primary outcome measure - The Western Ontario and McMaster Universities Arthritis Index (WOMAC) score and other measure EuroQol-Visual Analogue Scales (EQ-VAS) score, DFF\*, DFE\^ at 0, 6 ,12 and 24 weeks. The "Intervention" for 1st group was CCT and for the 2nd group was "No intervention". \* Deficient full flexion \^ Deficient full extension

Conditions

• Knee Osteoarthritis
• Arthroplasty
• Knee

Interventions

Type	Name	Description
OTHER	Contracture Correction Therapy	Non-drug and non-surgical treatment of contracted knee capsules

Timeline

• Start date: 2017-03-23
• Primary completion: 2017-12-30
• Completion: 2018-03-30
• First posted: 2020-08-03
• Last updated: 2023-07-25

Locations

6 sites across 1 country: India