| Not Yet Recruiting | Impact of Surgical Timing on Anal Fistula Outcomes NCT07482241 | Assiut University | — |
| Recruiting | Recurrence and Anal Fistula Patient Reported Outcomes Trial NCT07477496 | National and Kapodistrian University of Athens | — |
| Not Yet Recruiting | Determining the Effect of Education Given to Patients Undergoing Outpatient Anal Fistula Surgery NCT07323160 | Muğla Sıtkı Koçman University | N/A |
| Enrolling By Invitation | Study on the Mechanism of Zuoqing San Promoting Postoperative Wound Healing of Anal Fistula by Inhibiting ROS- NCT07128953 | The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine | EARLY_Phase 1 |
| Recruiting | Study on Repeat Liposomal Bupivacaine for Post-Surgery Pain in Anal Fistula Patients. NCT07081373 | Sixth Affiliated Hospital, Sun Yat-sen University | N/A |
| Not Yet Recruiting | Machine Learning-Based Risk Stratification for Fistula Formation After Perianal Abscess Drainage NCT07019532 | Gumushane State Hospital | — |
| Not Yet Recruiting | Cross-cultural Adaptation of the Chinese Version of QoLAF-Q (Quality of Life in Patients With Anal Fistula Que NCT06962228 | Changhai Hospital | — |
| Recruiting | Effect of Enhanced Recovery After Surgery for Benign Anorectal Conditions NCT06803550 | Mansoura University | N/A |
| Active Not Recruiting | Evaluating an rhPDGF-BB-enhanced Collagen Plug for Perianal Fistula Healing NCT06632418 | Alexander Hawkins | Phase 2 |
| Recruiting | Tissue Therapy of Transsphincteric Anal Fistula NCT06303752 | University of Southern Denmark | Phase 1 / Phase 2 |
| Not Yet Recruiting | Role of Autologous Platelet Rich Plasma(PRP) Injection and Platelet Rich Fibrin Glue(PRFG) Interposition for T NCT06092398 | Assiut University | N/A |
| Recruiting | Evaluate the Distribution and Dynamic Behavior of TH-SC01 Cells in Vivo in Patients With Perianal Fistula NCT06429241 | Jiangsu Topcel-KH Pharmaceutical Co., Ltd. | Phase 1 |
| Recruiting | A Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02 For the Manageme NCT05641844 | RedDress Ltd. | N/A |
| Unknown | Could Preoperative Assessment of Physical and Psychological Status Help Predict Pain After Anorectal Surgery? NCT06049524 | Center of Endourology "Endocenter" | — |
| Recruiting | Study on the Treatment of Anal Fistulas Using Alofisel Versus Fat Autologous Stem Cells NCT05974280 | Nantes University Hospital | — |
| Completed | Randomized Control Trial of Micronized Purified Flavonoid Fraction for Post Operative Treatment in Anal Fistul NCT06184438 | Taipei Medical University Shuang Ho Hospital | Phase 4 |
| Terminated | Ethibond Suture vs Vessel Loop as Draining Seton for Complex Anal Fistulas NCT05933343 | The Cleveland Clinic | N/A |
| Completed | Platelet- Rich Plasma Injection NCT06887166 | Mansoura University | N/A |
| Completed | Treatment of Ano-perineal Fistulas Resistant to Surgical Treatment with a Gel and Plug of Wharton's Jelly NCT05638139 | TBF Genie Tissulaire | Phase 1 |
| Unknown | BIOlogic Augmented Repair of Complex Anal Fistula Using Acellular Matrix and/or Autologous Platelet-rich Plasm NCT05805449 | The University of Texas Health Science Center, Houston | N/A |
| Completed | Hemostatic and Analgesic Effect of Gel Foam and Gauze With Bosmin After Anal Surgery NCT05605080 | Taipei Medical University Shuang Ho Hospital | N/A |
| Unknown | Re-routing in Treatment High Anal Fistula NCT05476146 | Assiut University | N/A |
| Unknown | Oral Antibiotics for Anal Abscess NCT03643198 | Germans Trias i Pujol Hospital | N/A |
| Recruiting | Myriad™ Augmented Soft Tissue Reconstruction Registry NCT05243966 | Aroa Biosurgery Limited | — |
| Unknown | Decompression and Drainage Seton for Treatment of High Horseshoe Anal Fistula NCT05044182 | China-Japan Friendship Hospital | N/A |
| Recruiting | Patient's Quality of Life and Functional Changes After Fistula Surgery NCT06548724 | Mansoura University Hospital | — |
| Unknown | Changes in Patients' Quality of Life With Differences in Seton Application NCT05348473 | Ankara University | N/A |
| Withdrawn | Mesenchymal Stem Cells for the Treatment of Pouch Fistulas in Crohn's NCT04073472 | The Cleveland Clinic | Phase 1 |
| Unknown | Rerouting Seton Versus LIFT for Complex Anal Fistula NCT04616911 | Mansoura University | N/A |
| Unknown | Adipose Tissue Injection for the Treatment of Complex Cryptoglandular Perianal Fistula NCT04790123 | Hospital Mutua de Terrassa | N/A |
| Unknown | Treatment of Perianal Fistulas by Endorectal Advancement Flap Associated With Adipose Tissue Injection NCT04750499 | Hospital Clinic of Barcelona | N/A |
| Unknown | Imaging Template for Reporting Anal Fistula NCT04541238 | Treviso Regional Hospital | — |
| Completed | The Modified Clipped-LIFT Procedure for High Transsphincteric or Suprasphincteric Fistula NCT07102134 | Sixth Affiliated Hospital, Sun Yat-sen University | N/A |
| Completed | Topical vs Oral Metronidazole After Benign Anorectal Surgery NCT05038605 | Mansoura University | N/A |
| Recruiting | E-CEL UVEC as an Adjunct Cell Therapy for Treatment of Anal Fistulas NCT04190862 | Weill Medical College of Cornell University | Phase 1 |
| Completed | Identifying Landmark Factors of Anal Fistulas NCT06421129 | Guanlin Liu | — |
| Unknown | Anal Fistula and Microdialysis - What is Yet to Learn? NCT04178707 | University Hospital, Umeå | N/A |
| Unknown | Laser Closure of Anal Fistula (FiLaC) NCT04161469 | Surp Pırgiç Armenian Hospital | N/A |
| Completed | LIFT With or Without Injection of BM-MNCs NCT05134168 | Mansoura University | N/A |
| Active Not Recruiting | Evaluation of the Recovery Rate and Postoperative Incontinence of Surgical Fistulas in a Cohort of a Reference NCT03865823 | Groupe Hospitalier Diaconesses Croix Saint-Simon | — |
| Completed | Ligation of Inter-sphincteric Fistula Tract for Management of Anal Fistula NCT05314205 | Al-Azhar University | — |
| Unknown | RCT on LIFT Versus Modified Parks Technique Versus Two-Stage Seton NCT04377542 | Mansoura University | N/A |
| Completed | INVESTIGATION OF THE EFFICACY OF FISTULA OBLITERATION BY STEAM ABLATION IN PERİANAL FISTULAS NCT04811105 | Fatih Sultan Mehmet Training and Research Hospital | N/A |
| Unknown | Management of Anal Fistula of Crohn Disease NCT03878498 | Rennes University Hospital | — |
| Completed | Stem Cells Treatment of Complex Crohn's Anal Fistula NCT03466515 | University of Southern Denmark | N/A |
| Completed | Marsupialization of Anal Fistulotomy Wound Accelerates Healing and Decreases Post Operative Pain NCT04155905 | Zagazig University | N/A |
| Completed | 3D Endoanal Ultrasound and Anal Fistula NCT03937752 | Region Skane | — |
| Completed | Treatment of Anal Fistulas With Obsidian RFT® NCT06136325 | Medical University of Vienna | — |
| Unknown | LIFT-plug vs LIFT, a RCT Trial NCT04310800 | Zhen Jun Wang | N/A |
| Unknown | Endorectal Three-dimensional Ultrasound in the Diagnosis of Cryptogenic Fistulas of the Rectum. NCT03743701 | State Scientific Centre of Coloproctology, Russian Federation | N/A |
| Unknown | Fistulectomy and Primary Sphincter rEconstruction vs. endorectaL Advancement Flap in the Treatment of High Ana NCT04119700 | Russian Society of Colorectal Surgeons | N/A |
| Unknown | Treatment of Transsphicteric Fistula-in-ano by Method of Laser Thermoobliteration(FiLaC™). NCT03690934 | State Scientific Centre of Coloproctology, Russian Federation | N/A |
| Unknown | LIFT Technique Versus Seton in Management of Anal Fistula NCT03311035 | Assiut University | N/A |
| Completed | Multicenter Prospective Evaluation of Radiofrequency for Anal Fistulas NCT03131297 | F Care Systems NV | N/A |
| Suspended | Treatment of Anal Fistula With Lasercoagulation NCT03017898 | Region Skane | N/A |
| Unknown | Randomized Trial on the Effect of Topical Phenytoin on Healing After Fistulotomy NCT03096522 | Mansoura University | N/A |
| Completed | Treatment of Complex Anal Fistula With Draining Seton With or Without Rerouting of Track NCT03636997 | Mansoura University | N/A |
| Completed | Fistulotomy With or Without Marsupialization for Treatment of Simple Anal Fistula NCT03595839 | Mansoura University | N/A |
| Completed | Treatment of Complex Anal Fistulas Using Centrifuged Adipose Tissue Containing Progenitor Cells NCT04326907 | University Hospital of Ferrara | N/A |
| Terminated | Endoscopic Treatment of Complex Anal Fistulas NCT02585167 | University of Southern Denmark | N/A |
| Completed | "Feasibility and Safety of the Calcium Alginate Hydrogel Sealant for the Treatment of Cryptoglandular Fistula- NCT04740086 | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | — |
| Completed | Ultrasound Guided Caudal Block for Benign Anal Surgery NCT03345511 | Universidad de Antioquia | N/A |
| Terminated | A Prospective Evaluation of the Strattice-LIFT to Treat Anal Fistula NCT02423330 | Rush University Medical Center | EARLY_Phase 1 |
| Unknown | Anal Fistulae Internal Opening Closure by OTSC Clip After Video Assisted Tract Fulguration NCT06243302 | Ankara University | — |
| Unknown | Surgical Treatment of High Perianal Fistulas NCT01997645 | University Hospital Hradec Kralove | N/A |
| Unknown | Effectiveness of Silver Nitrate Solution in the Treatment of Anal Fistula NCT01929525 | Marmara University | — |
| Completed | Clinical Trial to Evaluate the Efficacy and Safety of Stem Cells NCT01803347 | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | Phase 3 |
| Completed | Ligation of the Intersphincteric Fistula Tract (LIFT) + Biodesign for Anal Fistula NCT01602081 | Cook Group Incorporated | — |
| Unknown | Ligation of Intersphincteric Fistula Tract Versus Rectal Advancement Flap in the Treatment of Complex Anal Fis NCT05263661 | Hospital General Universitario Reina Sofía de Murcia | Phase 3 |
| Terminated | Gore-BioA Fistula Plug to Treat Transsphincteric Fistulas NCT01584752 | Central Finland Hospital District | — |
| Unknown | Anal Crohn Fistula Surgery NCT01388257 | French Society of Coloproctology | N/A |
| Completed | Long-term Follow-up of Anal Fistulae in Crohn's Disease Treated With Anti-TNFalpha and Interest of New MRI Seq NCT02883296 | Central Hospital, Nancy, France | N/A |
| Terminated | Study of GORE® BIO-A® Fistula Plug for Use in Anal Fistula Repair NCT01290666 | W.L.Gore & Associates | — |
| Recruiting | Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168 | Sanford Health | — |
| Unknown | The Efficacy of Human Acellular Dermal Matrix in the Treatment of Anal Fistula NCT00951002 | Zhen Jun Wang | — |
| Completed | Study to Assess the Safety and Efficacy of Expanded Allogenic Adipose-derived Stem Cells (eASCs) (Cx601), for NCT01372969 | Tigenix S.A.U. | Phase 1 / Phase 2 |
| Completed | Surgisis Anal Fistula Plug Study: An Experience in Saudi Arabia NCT00703131 | Cook Group Incorporated | — |
| Unknown | Ligation of Intersphincteric Fistula Tract (LIFT) Procedure Versus Use of an Anal Fistula Plug for Anal Fistul NCT00830661 | Colon and Rectal Surgery Associates, Ltd. | N/A |
| Completed | A Randomized Clinical Trial Comparing Surgisis AFP to Advancement Flap for the Repair of Anal Fistulas NCT00545441 | Cook Group Incorporated | N/A |
| Unknown | Anal Fistula Plug Versus Endorectal Advancement Flap NCT01931371 | University of Zurich | N/A |
| Terminated | Treatment of Crohn's Fistula Using a Porcine Intestine Submucosa Graft NCT00610207 | Cook Group Incorporated | N/A |
| Completed | Efficacy and Safety of Adipose Stem Cells to Treat Complex Perianal Fistulas Not Associated to Crohn´s Disease NCT00475410 | Tigenix S.A.U. | Phase 3 |
| Completed | Treatment of Perirectal Fistula With Cutting Seton vs. Collagen Plug NCT00450671 | University of Southern California | Phase 3 |
| Completed | Long-term Follow-up of Anal Fistula Plug NCT03961984 | Region Skane | — |
| Completed | Do Antibiotics Prevent Anal Fistulae Formation? NCT01012843 | Ankara University | N/A |
| Completed | Treatment of Anal Fistulas Advancement Flap NCT01042821 | Mansoura University | N/A |
| Unknown | Autologous Stem Cells Derived From Lipoaspirates for the Non-Surgical Treatment of Complex Perianal Fistula NCT00115466 | Cellerix | Phase 2 |