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UnknownNCT03096522

Randomized Trial on the Effect of Topical Phenytoin on Healing After Fistulotomy

A Randomized Controlled Trial on the Effect of Topical Phenytoin 2% on Wound Healing After Fistulotomy

Status
Unknown
Phase
N/A
Study type
Interventional
Enrollment
38 (estimated)
Sponsor
Mansoura University · Academic / Other
Sex
All
Age
16 Years – 65 Years
Healthy volunteers
Not accepted

Summary

Patients with anal fistula who will undergo anal fistulotomy will be randomized into one of two groups; the first group will receive topical phenytoin therapy postoperatively and the second group will not receive such topical treatment.

Detailed description

Patients with anal fistula who will undergo anal fistulotomy will be randomized into one of two groups; the first group will receive topical phenytoin therapy postoperatively and the second group will not receive such topical treatment. Healing of the wound after fistulotomy will be observed every week and the duration till complete healing will be recorded. The two groups will be compared regarding the mean duration till complete healing and postoperative complications.

Conditions

Interventions

TypeNameDescription
DRUGPhenytoin 2% sprayPatients will undergo anal fistulotomy then they will use phenytoin 2% spray topically on the anal wound resulting from fistulotomy with each sitz bath (twice per day) untill the anal wound heals completely
PROCEDUREAnal fistulotomyProbing of the fistula tract followed by lay open of the tract and curettage of granulation tissue in its base

Timeline

Start date
2017-02-20
Primary completion
2018-01-31
Completion
2018-03-30
First posted
2017-03-30
Last updated
2017-03-31

Locations

1 site across 1 country: Egypt

Source: ClinicalTrials.gov record NCT03096522. Inclusion in this directory is not an endorsement.