NCT04377542

RCT on LIFT Versus Modified Parks Technique Versus Two-Stage Seton

Randomized Controlled Trial on Ligation of Intersphincteric Fistula Tract (LIFT) Versus Modified Parks Technique Versus Two-Stage Seton In Treatment of Complex Anal Fistula

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 66 (actual)
• Sponsor: Mansoura University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

LIFT is a sphincter-saving procedure that is based on the concept of secure closure of the internal opening and concomitant removal of infected cryptoglandular tissue in the intersphincteric plane. Modified Parks technique involves adequate drainage of the intersphincteric space by extending the internal anal sphincterotomy. Placement of seton in the fistula track has been used for a long time and is still being currently used. Drainage two-stage seton is used to promote adequate drainage of infection and can be employed as a definitive treatment of anal fistula. This present randomized study aimed to compare LIFT, modified Parks technique, and two-stage seton in treatment of complex anal fistula in terms of success of treatment and complication rates.

Conditions

• Anal Fistula

Interventions

Type	Name	Description
PROCEDURE	LIFT	Ligation of the fistula tract in the intersphincteric plane
PROCEDURE	Parks	Modified Parks fistulotomy with complete internal anal sphincterotomy
PROCEDURE	Seton	Excision of the superficial part of fistula tract and tying loose seton around the remaining part and anal sphincter muscles

Timeline

• Start date: 2019-01-01
• Primary completion: 2019-12-01
• Completion: 2020-06-30
• First posted: 2020-05-06
• Last updated: 2020-05-06

Locations

1 site across 1 country: Egypt