| Not Yet Recruiting | Feasibility of Home Based Transcutaneous Spinal Cord Stimulation for Persons With SCI NCT06140706 | VA Palo Alto Health Care System | N/A |
| Not Yet Recruiting | A Clinical Trial to Evaluate the Safety and Efficacy of an Implantable Wireless Brain-Computer Interface（BCI）S NCT06990412 | Neuracle Medical Technology(Shanghai) Co.,Ltd. | N/A |
| Recruiting | Nerve Transfers Plus Electrical Stimulation to Improve Hand Function in Cervical Spinal Cord Injury NCT06541041 | Stanford University | — |
| Recruiting | Control Interfaces for Operating Assistive Devices NCT07058506 | Centre Bouffard Vercelli - USSAP | N/A |
| Not Yet Recruiting | Epidural Stimulation for Upper Extremity Function NCT06437548 | Brigham and Women's Hospital | N/A |
| Completed | Human Factors Validation Testing of the Wandercraft Personal Exoskeleton NCT06715631 | Wandercraft | N/A |
| Recruiting | Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01) NCT06511934 | Leigh R. Hochberg, MD, PhD. | N/A |
| Completed | Virtual Reality Upper Limb Therapy for People With Spinal Cord Injury NCT06154122 | Glasgow Caledonian University | N/A |
| Recruiting | Nerve Transfer to Improve Function in High Level Tetraplegia NCT06288763 | Washington University School of Medicine | — |
| Recruiting | Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia NCT05724173 | Leigh R. Hochberg, MD, PhD. | N/A |
| Recruiting | Clinical Trial to Evaluate the Safety and Efficacy of an Implantable Neural Acquisitor & Stimulator System in NCT05920174 | Neuracle Medical Technology(Shanghai) Co.,Ltd. | N/A |
| Recruiting | Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02) NCT06094205 | Leigh R. Hochberg, MD, PhD. | N/A |
| Unknown | Brain Controlled Spinal Cord Stimulation in Participants With Cervical Spinal Cord Injury for Upper Limb Rehab NCT05665998 | Ecole Polytechnique Fédérale de Lausanne | N/A |
| Unknown | Exopulse Mollii Suit, Motor Functions & CP Children With Cerebral Palsy NCT05885139 | Exoneural Network AB | N/A |
| Completed | Study Testing Benefits of Ursolic Acid (UA) as a Countermeasure To Myopenia and Insulin Resistance in Chronic NCT05776862 | University of Miami | Phase 2 |
| Completed | Neural Stimulation for Hand Grasp in People With Tetraplegia NCT05555914 | Centre Bouffard Vercelli - USSAP | N/A |
| Recruiting | MyHand-SCI: An Active Hand Orthosis for Spinal Cord Injury NCT05553457 | Columbia University | N/A |
| Completed | Extracorporeal Shockwave Therapy for Spasticity in People With Spinal Cord Injury NCT05432999 | Kessler Foundation | N/A |
| Withdrawn | Virtual Reality and Spinal Stimulation to Improve Arm Function NCT05065437 | Virginia Commonwealth University | N/A |
| Completed | Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI NCT05095454 | Kristin Zhao, PhD | N/A |
| Completed | The Effect of Robot Assisted Hand Therapy in Patients With Spinal Cord Injury NCT05726773 | Afyonkarahisar Health Sciences University | N/A |
| Recruiting | Investigation on the Cortical Communication (CortiCom) System NCT03567213 | Johns Hopkins University | N/A |
| Completed | Testing the Decision Aid: Supporting Patient Decisions About Upper Extremity Surgery in Cervical SCI NCT04995796 | Washington University School of Medicine | N/A |
| Completed | TETRAGRIP II - Usability Trial of an FES Orthosis for People With Tetraplegia. NCT04964635 | Bournemouth University | N/A |
| Completed | Epidural and Dorsal Root Stimulation in Humans With Spinal Cord Injury NCT04736849 | Peter J. Grahn, Ph.D. | N/A |
| Completed | Spinal Cord Injury Exercise and Nutrition Conceptual Engagement NCT03495986 | University of Miami | N/A |
| Unknown | Nerve Transfer Surgery to Restore Upper-limb Function After Cervical Spinal Cord Injury NCT05638191 | University of British Columbia | — |
| Completed | Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function NCT04777149 | Shepherd Center, Atlanta GA | N/A |
| Active Not Recruiting | Nerve Transfer After Spinal Cord Injury- Multi-center NCT04023591 | Washington University School of Medicine | — |
| Completed | Biofeedback Treatment of Anxiety Associated With Chronic Spinal Cord Injury NCT03975075 | Craig Hospital | N/A |
| Active Not Recruiting | Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury NCT04041063 | Burke Medical Research Institute | Phase 2 |
| Unknown | Functional Electrical Stimulation Cycling in SCI NCT04064385 | Glasgow Caledonian University | N/A |
| Unknown | NeuroCognitive Communicator: Safety Study NCT03100110 | Ottawa Hospital Research Institute | N/A |
| Recruiting | An Early Feasibility Study of the ReHAB System NCT03898804 | Jennifer Sweet, MD | N/A |
| Completed | Influence of Upper Extremity Vibration on Spasticity and Function in Persons With Tetraplegia NCT04020770 | Shepherd Center, Atlanta GA | N/A |
| Terminated | Elbow Extension Restoration Surgery in People With Tetraplegia: Evolution of the Muscular Co-activations of th NCT03513783 | Nantes University Hospital | N/A |
| Completed | Electrical Stimulation in Denervated Muscles of the Upper Limbs NCT03698136 | Swiss Paraplegic Research, Nottwil | N/A |
| Completed | Restoring High Dimensional Hand Function to Persons With Chronic High Tetraplegia NCT03482310 | VA Office of Research and Development | N/A |
| Recruiting | Evaluation of an Advanced Lower Extremity Neuroprostheses NCT00623389 | Case Western Reserve University | N/A |
| Completed | Enhancing Corticospinal Excitability to Improve Functional Recovery NCT03237091 | Shepherd Center, Atlanta GA | N/A |
| Unknown | [BrainConnexion] - Neurodevice Phase I Trial NCT03811301 | National Neuroscience Institute | N/A |
| Recruiting | Investigation on the Bidirectional Cortical Neuroprosthetic System NCT03161067 | Johns Hopkins University | N/A |
| Terminated | Stable and Independent Communication Brain-computer Interfaces NCT03213561 | Tomislav Milekovic | N/A |
| Unknown | Combined Robotic Training and tDCS in Chronic SCI NCT03555838 | Burke Medical Research Institute | Phase 3 |
| Completed | Conditioning Neural Circuits to Improve Upper Extremity Function NCT02611375 | Shepherd Center, Atlanta GA | N/A |
| Unknown | Functional Electrical Stimulation With Rowing as Exercise After Spinal Cord Injury NCT02602639 | University of Manitoba | N/A |
| Completed | Effect of Heat Exposure on Cognition in Persons With Tetraplegia NCT02488824 | VA Office of Research and Development | N/A |
| Completed | Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia NCT02379156 | James J. Peters Veterans Affairs Medical Center | Phase 4 |
| Completed | Exoskeletal-assisted Walking to Improve Mobility, Bowel Function and Cardio-Metabolic Profiles in Persons With NCT02314221 | James J. Peters Veterans Affairs Medical Center | N/A |
| Completed | The Safety of ahSC in Chronic SCI With Rehabilitation NCT02354625 | W. Dalton Dietrich | Phase 1 |
| Recruiting | Cortical Recording and Stimulating Array Brain-Machine Interface NCT01894802 | Michael Boninger | N/A |
| Active Not Recruiting | Spinal Cord Neuromodulation for Spinal Cord Injury NCT02313194 | University of California, Los Angeles | Phase 1 / Phase 2 |
| Completed | Omega-3 Supplementation for Tetraplegics With Poor Cholesterol Levels NCT01896037 | University of Manitoba | Phase 4 |
| Completed | A Neuroprosthesis for Prolonged Standing After SCI Using Multi-Contact Peripheral Nerve Electrodes NCT01923662 | VA Office of Research and Development | N/A |
| Completed | Providing Brain Control of Extracorporeal Devices to Patients With Quadriplegia NCT01849822 | Richard A. Andersen, PhD | N/A |
| Completed | Follow up Study of Diaphragm Pacing for Patients With High Tetraplegia NCT01815554 | Craig Hospital | — |
| Unknown | Nerve Transfer Reconstruction in the Tetraplegic Upper Extremity NCT01579604 | University of British Columbia | Phase 4 |
| Unknown | Improving Ambulatory Community Access After Paralysis NCT01570816 | Louis Stokes VA Medical Center | Phase 1 |
| Withdrawn | Study of the Impact of the Use of a Corset on the Respiratory Function of Patients With Spinal Cord Injury NCT01569360 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | Hand Function for Tetraplegia NCT00890916 | VA Office of Research and Development | N/A |
| Recruiting | A Neuroprosthesis for Seated Posture and Balance NCT01474148 | VA Office of Research and Development | N/A |
| Terminated | Spinal Cord Injury Leg Rehabilitation NCT01498991 | Oregon Health and Science University | Phase 1 / Phase 2 |
| Completed | Body Temperature in Persons With Tetraplegia When Exposed to Cold NCT01822535 | James J. Peters Veterans Affairs Medical Center | Phase 4 |
| Completed | ECoG Direct Brain Interface for Individuals With Upper Limb Paralysis NCT01393444 | University of Pittsburgh | N/A |
| Terminated | Microelectrode Brain-Machine Interface for Individuals With Tetraplegia NCT01364480 | Michael Boninger | N/A |
| Completed | Abdominal Functional Electrical Stimulation (AFES) to Assist Ventilator Weaning in Tetraplegia NCT02200393 | University of Glasgow | N/A |
| Completed | Sleep Disordered Breathing NCT01467856 | Mark S. Nash, Ph.D., FACSM | — |
| Completed | Diaphragmatic Reinnervation of Tetraplegic Patients With Respiratory Insufficiency NCT01350297 | University Hospital, Rouen | Phase 4 |
| Withdrawn | Effect of Air-stacking on Peak Cough Flow in Patients With Acute Cervical or High Thoracic Spinal Cord Injury NCT01046175 | Ullevaal University Hospital | Phase 2 |
| Completed | Brain Computer Interface for Communication in ICU: a Feasibility Study NCT01005524 | University of Versailles | — |
| Unknown | Body Composition Assessment in Spinal Cord Injury NCT00957762 | Hunter Holmes Mcguire Veteran Affairs Medical Center | — |
| Completed | Exhaled Breath Condensate Biomarkers of Inflammation in Individuals With Chronic Cervical Spinal Cord Injury NCT02235714 | James J. Peters Veterans Affairs Medical Center | — |
| Recruiting | BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia NCT00912041 | Leigh R. Hochberg, MD, PhD. | N/A |
| Completed | Rehabilitation of the Upper Extremity With Enhanced Proprioceptive Feedback Following Incomplete Spinal Cord I NCT00833105 | Oregon Health and Science University | N/A |
| Completed | Effects of Exercise in People With Tetraplegia NCT01202019 | University of Miami | N/A |
| Completed | Prospective Study on Swallowing/Breathing Interactions in Severe Guillain Barre Syndrome. NCT01024088 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Functional Melatonin Replacement for Sleep Disruptions in Individuals With Tetraplegia NCT00507546 | US Department of Veterans Affairs | Phase 4 |
| Completed | In-home Telerehabilitation for Quadriplegic Hand Function NCT00656149 | University of Alberta | Phase 2 / Phase 3 |
| Completed | Exhaled Levels of Nitric Oxide NCT00753948 | VA Office of Research and Development | Phase 2 / Phase 3 |
| Completed | Robotically Assisted Treadmill Training in Spinal Cord Injury (SCI) NCT00385918 | US Department of Veterans Affairs | N/A |
| Completed | Reach and Palmar Grasp in Tetraplegics With Neuromuscular Electrical Stimulation: Assessment and Training. NCT02969772 | Enio Walker Azevedo Cacho | N/A |
| Unknown | Abdominal Functional Electrical Stimulation in Tetraplegia NCT00202631 | South Glasgow University Hospitals NHS Trust | N/A |
| Completed | Evaluation of Breathing Pattern and Dyspnea in Subjects With Tetraplegia NCT00904436 | US Department of Veterans Affairs | N/A |
| Active Not Recruiting | Implanted Myoelectric Control for Restoration of Hand Function in Spinal Cord Injury NCT00583804 | MetroHealth Medical Center | N/A |