NCT01393444

ECoG Direct Brain Interface for Individuals With Upper Limb Paralysis

Acute Electrocorticography (ECoG) Direct Brain Interface for Individuals With Upper Limb Paralysis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 6 (actual)
• Sponsor: University of Pittsburgh · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research study is to demonstrate that individuals with upper limb paralysis due to spinal cord injury, brachial plexus injury, amyotrophic lateral sclerosis and brain stem stroke can successfully achieve direct brain control of assistive devices using an electrocorticography (ECoG)-based brain computer interface system.

Detailed description

Brain-computer interface (BCI) technology aims to establish a direct link for transmitting information between the brain and external devices, offering a natural and rich control signal for prosthetic hands or functional electrical stimulators (FES) to re-animate paralyzed hands. This study focuses on an ECoG-based BCI system. ECoG measures brain activity using electrodes implanted on the surface of the brain. Each participant will undergo testing of the ECoG direct brain interface for up to 29 days. Participants will learn to control computer cursors, virtual reality environments, and assistive devices such as hand orthoses and functional electrical stimulators using neural activity recorded with the ECoG sensor.

Conditions

• Tetraplegia
• Spinal Cord Injury
• Brachial Plexus Injury
• Muscular Dystrophy
• ALS
• Brainstem Stroke

Interventions

Type	Name	Description
DEVICE	Implantation of ECoG sensors on the brain surface	One ECoG sensor will be implanted over the motor cortex of study participants

Timeline

• Start date: 2011-05-01
• Primary completion: 2015-04-01
• Completion: 2015-04-01
• First posted: 2011-07-13
• Last updated: 2016-12-12
• Results posted: 2016-12-12

Locations

1 site across 1 country: United States