| Not Yet Recruiting | Safety and Preliminary Efficacy of HN2302 in Patients With Autoimmune Diseases NCT07523282 | Shenzhen MagicRNA Biotechnology Co., Ltd | Phase 1 |
| Not Yet Recruiting | A Study of BEN301 Injection in theTreatment of Autoimmune Diseases NCT07527936 | RenJi Hospital | EARLY_Phase 1 |
| Not Yet Recruiting | A Phase I/Ⅱ Clinical Trial for HS_SW01 Cells Injection in the Treatment of Systemic Sclerosis NCT07535931 | Shenzhen Huishan Biotechnology Co., Ltd. | Phase 1 / Phase 2 |
| Recruiting | Allogeneic CD19/BCMA CAR-T for B Cell-Related Autoimmune Disease NCT07507201 | The Children's Hospital of Zhejiang University School of Medicine | EARLY_Phase 1 |
| Recruiting | Controlling Hyperactive Immunity With Long-lived Lymphocytes NCT07473154 | Quell Therapeutics Limited | Phase 1 / Phase 2 |
| Recruiting | MTS109 in Patients With Refractory Autoimmune Diseases NCT07526350 | Shanghai Changzheng Hospital | EARLY_Phase 1 |
| Recruiting | Systemic Sclerosis DIet for GastrointESTinal Symptoms NCT07402226 | University of Michigan | N/A |
| Recruiting | Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic D NCT07087912 | University of Sao Paulo General Hospital | Phase 4 |
| Not Yet Recruiting | Correlation Between Circulating Fibroblast Activation Protein (FAP) and Fibrosis in Two Diseases (Rheumatoid A NCT07393217 | Sohag University | — |
| Withdrawn | A Study to Assess CLBR001+SWI019 in Subjects With Autoimmune Diseases NCT06913608 | Calibr, a division of Scripps Research | Phase 1 |
| Recruiting | A Clinical Study of TI-0032-III Injection in Patients With Relapsed and Refractory Autoimmune Diseases NCT07413341 | Therorna | Phase 1 |
| Recruiting | Safety and Efficacy of Adipose-Derived Regenerative Cells (ADRCs) for Improving Hand Dysfunction in Systemic S NCT07360808 | Cytori Therapeutics | N/A |
| Not Yet Recruiting | Clinical Study of BCT301 Cell Injection Therapy for Refractory Autoimmune Diseases NCT07301164 | Peking University Third Hospital | EARLY_Phase 1 |
| Recruiting | Investigating the Effectiveness of the Biopsychosocial Model-Based Exercise Approach in Children and Adults Di NCT07292961 | Hacettepe University | N/A |
| Recruiting | CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B Cell Mediated Autoimmune Disease NCT07305116 | The Children's Hospital of Zhejiang University School of Medicine | Phase 1 |
| Recruiting | A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101 NCT07403188 | Kyverna Therapeutics | — |
| Recruiting | Topical Cannabidiol Lotion for Pruritus Relief in Scleroderma NCT07245238 | Khon Kaen University | Phase 3 |
| Recruiting | Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography Images NCT07228429 | Yale University | — |
| Recruiting | A Study of OL-CD19-GDT in Relapsed/ Refractory Autoimmune Diseases NCT07167537 | Beijing GoBroad Hospital | Phase 1 |
| Not Yet Recruiting | Mass Spectrometry-based Immune Profiling in Autoimmune Diseases NCT07188285 | Peking University People's Hospital | — |
| Not Yet Recruiting | A Study of GB261 in Systemic Sclerosis NCT07159009 | Ruijin Hospital | EARLY_Phase 1 |
| Not Yet Recruiting | A Study of Cizutamig in Systemic Sclerosis NCT07158996 | Ruijin Hospital | EARLY_Phase 1 |
| Recruiting | Clinical Study of BCMA/CD70-targeted CAR-T Therapy for Refractory Pediatric Rheumatic Diseases NCT07184450 | Chongqing Precision Biotech Co., Ltd | Phase 1 |
| Not Yet Recruiting | GC012F in Patients With Autoimmune Diseases NCT07072884 | Qiong Fu | EARLY_Phase 1 |
| Recruiting | Cultural Adaptation, Validity, and Reliability of the Turkish Version of The PASTUL Questionnaire NCT07182968 | Hacettepe University | — |
| Recruiting | A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases NCT07104721 | China Immunotech (Beijing) Biotechnology Co., Ltd. | Phase 1 |
| Recruiting | Patients Diagnosed With Scleroderma: Physical Performance and Functionality NCT07183072 | Hacettepe University | — |
| Recruiting | Patients Diagnosed With Scleroderma and Their Chewing and Swallowing Performance NCT07182981 | Hacettepe University | — |
| Recruiting | AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Ritux NCT06991114 | Artiva Biotherapeutics, Inc. | Phase 2 |
| Recruiting | Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refractory Autoimmune Diseases NCT06828042 | Peking University Third Hospital | Phase 1 / Phase 2 |
| Not Yet Recruiting | PPI Refractory - GERD Mechanisms in Systemic Sclerosis NCT07022912 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Not Yet Recruiting | Clinical Study on the Treatment of Systemic Sclerosis With UTAA91 Injection. NCT06982534 | PersonGen BioTherapeutics (Suzhou) Co., Ltd. | EARLY_Phase 1 |
| Recruiting | A Study of OL-108 in Relapsed/Refractory Autoimmune Diseases NCT06980597 | Beijing GoBroad Hospital | Phase 1 |
| Recruiting | Multicenter Study on the Development of Pulmonary Arterial Hypertension Screening Models Based on Artificial I NCT07236970 | Alejandro Cruz Utrilla | — |
| Recruiting | The Clinical Study on the Treatment of SSc With UTAA91 Injection. NCT07000682 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | EARLY_Phase 1 |
| Recruiting | A Clinical Study of YTS109 Cell in R/R Autoimmune Diseases NCT06978647 | China Immunotech (Beijing) Biotechnology Co., Ltd. | Phase 1 |
| Recruiting | Clinical Assessment for Rheumatologic Disease - Research and Advancement in Safety and Efficacy NCT07150000 | University of Bonn | — |
| Recruiting | Intralesional Injection of STS in Treatment of Calcinosis NCT06672822 | Robyn T. Domsic, MD, MPH | Phase 2 |
| Recruiting | Home-Based Clinical Management of Cardiac Complications in Systemic Sclerosis NCT06865118 | Oslo University Hospital | — |
| Not Yet Recruiting | Chester Step Test: is It Effective in Scleroderma Patients? NCT06859567 | Firat University | N/A |
| Not Yet Recruiting | Safety and Efficacy of Universal CAR-T Cells (UWD-CD19) Combined with Immunosuppressants in the Treatment of R NCT06821659 | Peking University Third Hospital | Phase 1 / Phase 2 |
| Recruiting | CT1190B in the Treatment of Patients With Moderate to Severe Refractory Systemic Lupus Erythematosus (SLE) or NCT06822881 | Beijing GoBroad Hospital | Phase 1 |
| Recruiting | CAR T-cell Therapy Targeting CD19 and BCMA in Patients With Relapse/Refractory Autoimmune Diseases NCT06941129 | Institute of Hematology & Blood Diseases Hospital, China | Phase 1 |
| Recruiting | Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE) NCT06843239 | Zura Bio Inc | Phase 2 |
| Completed | Evaluating the Effect of Questionnaire Context on the Reporting of Somatic Items Among People With Systemic Sc NCT06772896 | Lady Davis Institute | N/A |
| Not Yet Recruiting | Relationship Between Pelvic Floor Dysfunctions and Sexual Dysfunction in Female Patients with Systemic Scleros NCT06769399 | Istanbul University - Cerrahpasa | — |
| Recruiting | The Apollo Device in Systemic Sclerosis for the Management of fatiguE, Raynaud Phenomenon and qualiTy of Life NCT06675344 | Robyn T. Domsic, MD, MPH | N/A |
| Recruiting | Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases NCT06614270 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Not Yet Recruiting | US Zamto-cel Autoimmune Diseases NCT06708845 | Miltenyi Biomedicine GmbH | Phase 1 |
| Recruiting | BCMA-CD19 CAR-T Therapy for Refractory Autoimmune Diseases NCT06794008 | Peking University People's Hospital | Phase 2 |
| Recruiting | Clinical Study of CD19 CAR-T in the Treatment of Refractory Systemic Sclerosis NCT06792344 | The Children's Hospital of Zhejiang University School of Medicine | Phase 1 |
| Recruiting | DERMATOMICS: Identifying Regulators of Skin Homeostasis NCT06894654 | Relation Therapeutics | — |
| Recruiting | A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis NCT06655155 | argenx | Phase 2 |
| Enrolling By Invitation | A Phase 1 Study of Prulacabtagene Leucel (Prula-cel, Formerly ADI-001) in Autoimmune Disease NCT06375993 | Adicet Therapeutics | Phase 1 |
| Recruiting | Safety Study of CC312 in Autoimmune Disease Patients NCT06888960 | CytoCares Inc | EARLY_Phase 1 |
| Enrolling By Invitation | Hand ScleroDerma Lived Experience Scale in Individuals With Systemic Sclerosis NCT06658483 | Pamukkale University | — |
| Enrolling By Invitation | Hand Disability In Systemic Sclerosis - Digital Ulcers NCT06658470 | Pamukkale University | — |
| Not Yet Recruiting | 6-minute Pegboard Ring Test in Patients With Scleroderma NCT06588959 | Yasemin GEDIKLI | — |
| Not Yet Recruiting | Nailfold Capillaroscopic Pattern Changes and Its Correlation with Interstitial Lung Disease (ILD) in Systemic NCT06579651 | Assiut University | — |
| Recruiting | Rare AutoImmune SElf-management Programme Development NCT06642870 | University of the West of England | — |
| Recruiting | TENS in Scleroderma NCT06646913 | University of Michigan | Phase 1 |
| Recruiting | Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases NCT07085676 | Polina Stepensky | Phase 1 |
| Recruiting | Investigation of Respiratory Muscle Sarcopenia in Patients With Systemic Sclerosis NCT06598982 | Selcuk University | — |
| Recruiting | A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease NCT06308978 | Fate Therapeutics | Phase 1 |
| Recruiting | A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy NCT06249438 | RenJi Hospital | Phase 1 |
| Completed | As Part of a Pilot Study, Visualization of Inflammatory Activity in Systemic Sclerosis Using CXCR4 PET/CT NCT07212959 | Wuerzburg University Hospital | N/A |
| Recruiting | Interferon Signature in Anti-CTLA-4 and Anti-PD-1/PD-L1-Treated Cancer Patients Compared With Systemic Autoimm NCT07249060 | Hospital Universitario Araba | — |
| Recruiting | Functional Performance and Biopsychosocial Characteristics in Individuals with Systemic Sclerosis NCT06594302 | Hacettepe University | — |
| Recruiting | Assessment of Nutritional Status in Rheumatic Diseases and Association to Disease Activity NCT07277491 | Cairo University | — |
| Terminated | COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders NCT05000216 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 2 |
| Completed | 7.0 Tesla Resonance Magnetic Imaging of the Hand in Systemic Sclerosis NCT04223817 | Poitiers University Hospital | N/A |
| Completed | Subcutaneous Doses of CM-101 as a Treatment for Medical Conditions Involving Inflammatory and Fibrotic Mechani NCT06037577 | ChemomAb Ltd. | Phase 1 |
| Unknown | Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases NCT01151644 | University of Sao Paulo | Phase 4 |