Trials / Recruiting
RecruitingNCT07228429
Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography Images
Quantification of Calcinosis Cutis Disease Burden in Patients With Systemic Sclerosis Using Computed Tomography Images
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 56 (estimated)
- Sponsor
- Yale University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The main purpose of this study is to develop sensitive radiographic measurement techniques that can be used as outcome measures along with patient-reported outcome instruments in clinical trials of calcinosis cutis treatments, and potentially be used to assess disease course and treatment response in clinical practice. The goal is to test the performance of the software.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Sodium Thiosulfate (STS) | Calcinosis cutis treatment, 25% STS topical cream, Twice daily for 6 months |
| DRUG | Sodium Thiosulfate Injection | calcinosis cutis treatment, 25% STS intradermal injection, once monthly for 6 months |
Timeline
- Start date
- 2025-10-14
- Primary completion
- 2026-07-01
- Completion
- 2026-07-01
- First posted
- 2025-11-14
- Last updated
- 2026-02-17
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT07228429. Inclusion in this directory is not an endorsement.