Clinical Trials Directory

Trials / Conditions / Refractory Cancer

Refractory Cancer

55 registered clinical trials studyying Refractory Cancer20 currently recruiting.

StatusTrialSponsorPhase
RecruitingA Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants
NCT06634589
BeOne MedicinesPhase 1 / Phase 2
RecruitingAllogeneic NKG2DL-targeting CAR γδ T Cells (CTM-N2D) in Advanced Cancers (ANGELICA)
NCT05302037
CytoMed Therapeutics Pte LtdPhase 1
RecruitingPlan Development for Giving Teclistamab in the Outpatient Setting
NCT06251076
University Health Network, TorontoPhase 4
WithdrawnA Study of RO7617991 in Patients With Locally Advanced or Metastatic MAGE-A4-Positive Solid Tumors
NCT06372574
Genentech, Inc.Phase 1
RecruitingOptimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer
NCT06208657
Australian & New Zealand Children's Haematology/Oncology GroupPhase 1 / Phase 2
RecruitingZanubrutinib With Pemetrexed to Treat Relapsed/Refractory Primary and Secondary Central Nervous System (CNS) L
NCT05681195
Baptist Health South FloridaPhase 2
RecruitingAutologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC
NCT06096038
UNC Lineberger Comprehensive Cancer CenterPhase 1 / Phase 2
RecruitingA Dose Escalation and Expansion Study of [177Lu]Lu-SN201 in Participants With Advanced Cancer
NCT06184035
Spago Nanomedical ABPhase 1 / Phase 2
Active Not RecruitingIndividualized Treatments in Adults With Relapsed/Refractory Cancers
NCT06024603
Case Comprehensive Cancer CenterN/A
RecruitingSafety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy i
NCT05852717
Dipenkumar ModiPhase 2
RecruitingA Study of Avutometinib for People With Solid Tumor Cancers
NCT06104488
Memorial Sloan Kettering Cancer CenterPhase 1
RecruitingLeflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS Mutations
NCT06229340
N.N. Petrov National Medical Research Center of OncologyPhase 2
CompletedStudy of Allogeneic Blood-derived Natural Killer Cells to Evaluate Safety and Tolerability in Cancer Refractor
NCT05990920
NKGen Biotech, Inc.Phase 1
RecruitingIMA402 T Cell-Engaging Receptor Molecule (TCER®) in Recurrent and/or Refractory Solid Tumors
NCT05958121
Immatics Biotechnologies GmbHPhase 1 / Phase 2
Active Not RecruitingA Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid
NCT05864144
Sensei Biotherapeutics, Inc.Phase 1 / Phase 2
RecruitingA Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer
NCT05859074
Memorial Sloan Kettering Cancer CenterPhase 1
RecruitingPhase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
NCT05856981
Sairopa B.V.Phase 1
RecruitingA Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tu
NCT05669430
GV20 TherapeuticsPhase 1 / Phase 2
Active Not RecruitingA Study of HST-1011 Given as Monotherapy and in Combination With an Anti-PD1 Antibody
NCT05662397
HotSpot Therapeutics, IncPhase 1 / Phase 2
TerminatedStudy of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancr
NCT05631574
Biomea Fusion Inc.Phase 1
RecruitingPrecision Medicine for Every Child With Cancer
NCT05504772
Australian & New Zealand Children's Haematology/Oncology Group
UnknownmyCare-102: Clinical Utility and Usability of Cellworks Singula™ and Cellworks Ventura™ Reports
NCT05693831
Cellworks Group Inc.
WithdrawnStudy to Assess an Anti-Trop2 Antibody Drug Conjugate in Relapsed or Refractory Solid Tumors
NCT05060276
Sorrento Therapeutics, Inc.Phase 1
RecruitingA Phase I, First in Human Study of CBA-1535, T Cell Engager(5T4/CD3/5T4) in Patients With Advanced Solid Tumor
NCT07016997
Chiome Bioscience Inc.Phase 1
Active Not RecruitingIMA401 TCER® in Recurrent and/or Refractory Solid Tumors, Alone or in Combination With a Checkpoint Inhibitor
NCT05359445
Immatics Biotechnologies GmbHPhase 1
RecruitingStudy of Pembrolizumab With Bendamustine in Hodgkin Lymphoma
NCT04510636
University Health Network, TorontoPhase 2
CompletedA Study of the Safety and PK of PCS6422 (Eniluracil) with Capecitabine in Patients with Advanced, Refractory G
NCT04861987
Processa PharmaceuticalsPhase 1
UnknownA Study of MPT-0118 in Subjects With Advanced or Metastatic Refractory Solid Tumors
NCT04859777
Monopteros Therapeutics Inc.Phase 1
CompletedImpact of Human-Animal Interactions on Children With Life-Threatening Conditions and Their Parents
NCT04310345
Vanderbilt-Ingram Cancer CenterN/A
UnknownEfficacy and Safety of PVT-1 Treatment in Patients With Advanced Non-Small Cell Lung Cancer
NCT04840004
PlusVitech S.L.Phase 2
RecruitingFatty Acid Synthase Inhibition in Castration Refractory Prostate Cancer
NCT04337580
Wake Forest University Health SciencesPhase 2
UnknownStudy of TBX-3400 in Subjects With Solid Malignant Tumors Resistant or Refractory to Standard Therapies
NCT04640246
Taiga Biotechnologies, Inc.Phase 1 / Phase 2
UnknownArsenic Trioxide for Structural p53 Mutations
NCT04695223
Shanghai Changzheng HospitalPhase 2
TerminatedStudy of Enasidenib and Venetoclax in IDH2-Mutated Blood Cancers
NCT04092179
University Health Network, TorontoPhase 1 / Phase 2
RecruitingPembrolizumab, Ibrutinib and Rituximab in PCNSL
NCT04421560
Dana-Farber Cancer InstitutePhase 1 / Phase 2
Terminated9-ING-41 in Pediatric Patients With Refractory Malignancies.
NCT04239092
Actuate Therapeutics Inc.Phase 1
CompletedSafety of SNK01 in Subjects With Pathologically Confirmed Metastatic and/or Unresectable Cancer Refractory to
NCT03941262
NKGen Biotech, Inc.Phase 1
RecruitingACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Sol
NCT03686124
Immatics US, Inc.Phase 1 / Phase 2
CompletedTCR-engineered T Cells in Solid Tumors: IMA202-101
NCT03441100
Immatics US, Inc.Phase 1
CompletedHuman Leukocyte Antigen Typing and Tumor Antigen Expression Profiling
NCT03760952
Immatics US, Inc.
CompletedAnimal-Assisted Interactions in Children With Life-Threatening Conditions and Their Parents
NCT03765099
Vanderbilt-Ingram Cancer CenterN/A
Active Not Recruiting9-ING-41 in Patients With Advanced Cancers
NCT03678883
Actuate Therapeutics Inc.Phase 2
CompletedStudy of CFI-400945 Fumarate in Patients With Relapsed or Refractory AML or MDS
NCT03187288
University Health Network, TorontoPhase 1
CompletedPembrolizumab in Combination With Decitabine and Hypofractionated Index Lesion Radiation in Pediatrics and You
NCT03445858
Children's Hospital Medical Center, CincinnatiEARLY_Phase 1
CompletedA Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination With Immune Checkpoint Inhibition in Refractory
NCT03206073
National Cancer Institute (NCI)Phase 1 / Phase 2
Active Not RecruitingPRecISion Medicine for Children With Cancer
NCT03336931
Sydney Children's Hospitals Network
UnknownA Clinical Study of Apatinib in Patients With Local Progressive/Metastatic Refractory Thyroid Cancer
NCT03199677
Chinese Academy of Medical SciencesPhase 2
UnknownStudy of Ibrutinib in Combination With Bendamustine and Rituximab for Patients With Relapsed/Refractory Aggres
NCT02747732
Meirav Kedmi MDPhase 2
CompletedStudy of AZD6738, DNA Damage Repair/Novel Anti-cancer Agent, in Combination With Paclitaxel, in Refractory Can
NCT02630199
Samsung Medical CenterPhase 1
TerminatedStudy of Safety and Tolerability of VLX600, an Iron Chelator, in Patients With Refractory Advanced Solid Tumor
NCT02222363
Vivolux ABPhase 1
TerminatedBIBW 2992 (Afatinib) for the Treatment of Patients With HER2-positive, Hormone-refractory Prostate Cancer
NCT01320280
Universitätsklinikum Hamburg-EppendorfPhase 2
UnknownPatients Who Refractory Cancer Conqueror for Bio New Drug Development Translational Research Establishment
NCT01932047
Samsung Medical Center
CompletedA Safety Study of an Oral EGFR Inhibitor, AV-412, Administered Three Times Weekly in Advanced Solid Tumor Pati
NCT00551850
AVEO Pharmaceuticals, Inc.Phase 1
CompletedMolecular Profiling Protocol (SCRI-CA-001)
NCT00530192
Scottsdale HealthcareEARLY_Phase 1
CompletedPhase I Trial of Tariquidar (XR9576) in Combination With Doxorubicin, Vinorelbine, or Docetaxel in Pediatric P
NCT00011414
National Cancer Institute (NCI)Phase 1