| Not Yet Recruiting | Effects of Topical Anesthesia Approaches on Dental Pain During and After Restorative Management of Dental Cari NCT07379515 | Dubai Health | N/A |
| Not Yet Recruiting | Clinical and Radiographic Evaluation of Primary Endodontic Treatment and Non-surgical Endodontic Retreatments NCT07418840 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Not Yet Recruiting | Measurement of Pro-resolving Inflammation Biomarkers in Saliva, Gingival Fluid, and Dental Pulp in Patients Wi NCT07450235 | Université de Nantes | — |
| Recruiting | Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker NCT07452614 | Abeer Ghalib Abdul-khaliq | N/A |
| Not Yet Recruiting | Comparison of Aquaporin -4, -5, -9 and IL-8 Levels in GCF, Dentin Fluid and Pulp Samples NCT06938191 | Kırıkkale University | — |
| Recruiting | Effectiveness of Pulpotomy vs. Root Canal Treatment in Extremely Deep Caries NCT07242742 | National University Hospital, Singapore | N/A |
| Recruiting | Success of Endodontic Treatment With Different Obturation Techniques and Sealer Cements NCT07019298 | University of Siena | N/A |
| Recruiting | Postoperative Pain Evaluation After Obturation With Different Sealers NCT07018284 | University of Siena | N/A |
| Active Not Recruiting | The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy NCT07130214 | Ataturk University | — |
| Completed | Comparison of IL-8, FGF-1 and VEGF Levels in Pulpal Tissue, GCF and Dentinal Fluid Samples of Healthy, Reversi NCT06936553 | Kırıkkale University | — |
| Completed | Photodynamic Therapy and Post-Endodontic Pain in Undergraduate-Performed Treatments NCT07254260 | Atlas University | — |
| Not Yet Recruiting | Caries Location and Its Effect on the Success Rate of Indirect Pulp Treatment in Primary Molars NCT06675058 | Cairo University | N/A |
| Completed | Success of Pulpotomy in Molars With Pulpitis With Periodontitis Detected Using AI and Those Without Periodonti NCT06767371 | Misr International University | N/A |
| Active Not Recruiting | Clinical and Radiographic Evaluation of Propolis As a Hemostatic Agent for Pulpotomy of Mature Permanent Molar NCT06679075 | Misr International University | Phase 2 |
| Completed | Evaluation of Pulpal and Salivary Neuropeptides in Dental Pain NCT07330024 | Kahramanmaras Sutcu Imam University | — |
| Not Yet Recruiting | Evaluation of Pulpotomy Using Two Different Agents in Mature Anterior Teeth With Pulpitis NCT06468085 | Ain Shams University | N/A |
| Recruiting | The Effect of Different Risk Factors on the Success Rate of VPT NCT06844448 | Semmelweis University | — |
| Completed | The Effect of Cryotherapy on the Outcome of Pulpotomy and Root Canal Treatment NCT06183021 | Ondokuz Mayıs University | N/A |
| Unknown | Intraligamentary Injections and Post-endodontic Pain NCT06186921 | Jamia Millia Islamia | N/A |
| Completed | A Clinical Trial Comparing FS With ZOE and Non-eugenol Based Materials in Primary Teeth Pulpotomies NCT05557812 | Virginia Commonwealth University | EARLY_Phase 1 |
| Unknown | Clinical and Radiographic Evaluation of Laser Photobiomodulation Pulpotomy of Primary Molars in Children NCT05850780 | Aliaa Hamouda | N/A |
| Completed | Hydraulic Cements in Partial Pulpotomy NCT06881615 | Universidad Europea de Madrid | N/A |
| Completed | Efficacy of Pediatric Rotary File System Versus Hand Instrumentation for Root Canal Preparation in Primary Tee NCT06152354 | Suez Canal University | N/A |
| Completed | Effect of Cryotherapy and LLLT on Postoperative Pain After Root Canal Treatment NCT05476445 | Ataturk University | N/A |
| Completed | Use of Tramadol Intraligamentary Injections NCT05538052 | Jamia Millia Islamia | N/A |
| Completed | Pulpotomy Materials in Primary Molars NCT07120321 | Sacide Duman | N/A |
| Completed | Post-Operative Pain After Vital Pulpotomy in Molars With Symptomatic Pulpitis NCT06216951 | Uşak University | — |
| Completed | Bioactive Materials in Pulp Therapy of Primary Teeth NCT04795830 | Ain Shams University | Phase 4 |
| Completed | Vital Pulp Therapy vs. Root Canal Treatment in Mature Teeth With Irreversible Pulpitis NCT07355140 | Universidad Central de Venezuela | N/A |
| Completed | Intentional Pulpotomy to Preserve Hopeless Molars NCT04385693 | University of Florida | N/A |
| Completed | The Use of Platelet-Rich Fibrin in Partial Pulpotomy Procedure NCT04331964 | Damascus University | N/A |
| Completed | Efficacy of Combining an Inferior Alveolar Nerve Block With a Buccal Infiltration NCT06276842 | CIMS Dental College | Phase 1 / Phase 2 |
| Completed | Evaluation of Hyaluronic Acid Pulpotomies in Primary Molars NCT04115358 | Marmara University | N/A |
| Completed | Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer NCT04365270 | Ain Shams University | Phase 3 |
| Unknown | Post-operative Pain in 2Shape Versus Protaper Next Rotary Systems NCT03694743 | Cairo University | N/A |
| Unknown | Celebrex Premedication in Teeth With Symptomatic Irreversible Pulpitis NCT03339544 | Cairo University | N/A |
| Completed | Comparative Evaluation of Different File Systems in Postoperative Pain NCT03708081 | Bulent Ecevit University | — |
| Completed | Efficacy of Oral Prednisolone on Pain Reduction in Emergency Care of Acute Irreversible Pulpitis NCT02629042 | University Hospital, Bordeaux | Phase 3 |
| Completed | MMP-9 Expression in Permanent Mature Teeth With Symptomatic Pulpitis NCT03807674 | Eglė Gvazdaitytė | N/A |
| Unknown | Comparison Between Reciproc and Oneshape Systems NCT02940782 | Cairo University | N/A |
| Completed | Assessment of Postoperative Pain After Using Reciproc Versus One Shape NiTi Systems NCT02940704 | Cairo University | N/A |
| Completed | Evaluation of Dentinal Fluid for the Presence of Matrix Metalloproteinase 9 (MMP-9) in Pulpal Inflammation NCT02967081 | University of Zurich | — |
| Completed | Comparative Evaluation of Pulpal Anaesthetic Efficacy of Different Anaesthetic Solutions for Inferior Alveolar NCT05239078 | Dr. Vivek Aggarwal | N/A |
| Completed | Validation of PUFA Index in Assessing Untreated Dental Caries Among Malaysian Adult Subpopulation NCT04126928 | Universiti Kebangsaan Malaysia Medical Centre | N/A |
| Completed | Indirect Pulp Capping With Resin Modified Glass Ionomer NCT02494193 | Universidade Federal de Sergipe | N/A |
| Completed | Effect of Glass Ionomer Cement as an Interim Restoration in Diagnosis of Pulpal Status NCT03168620 | Postgraduate Institute of Dental Sciences Rohtak | N/A |
| Completed | Anesthetic Efficacy of 1,8mL and 3,6mL of Articaine in Inferior Alveolar Nerve Block in Irreversible Pulpitis NCT02422823 | Isabel Peixoto Tortamano | N/A |
| Completed | Clinical and Microbiological Evaluation of 0.5% Versus 3% Sodium Hypochlorite in Root Canal Treatment NCT02681276 | Göteborg University | N/A |
| Unknown | A Study of the Trigeminal Cardio-Reflex in Endodontic and Other Dental Treatment NCT02745782 | YI SHENG HUANG | — |
| Unknown | Success Rate Evaluation of Miniature Pulpotomy With MTA in Primary Molars NCT02286648 | Mashhad University of Medical Sciences | Phase 4 |
| Completed | Postoperative Pain Intensity After Using Different Instrumentation Techniques: a Randomized Clinical Study NCT02566486 | Bulent Ecevit University | N/A |
| Completed | Pulpotomy in Carious Permanent Mature Teeth: Pulp Survival and Risk Factors NCT03490422 | National University Health System, Singapore | N/A |
| Completed | Effect of Low Power Laser in Tooth Pain Modulation Caused by Irreversible Inflammation NCT02169102 | University of Sao Paulo | N/A |
| Completed | Oral Glucocorticoids Effect on Post Endodontic Pain NCT02819648 | Cairo University | Phase 4 |
| Completed | Partial Pulpotomy on Caries Free Human Teeth NCT01420718 | Islamic Azad University, Sanandaj | Phase 2 / Phase 3 |
| Completed | Assessing of Tooth Sensitivity Using Ibuprofen Before in Office-tooth Bleaching NCT01530217 | Universidade Estadual de Ponta Grossa | N/A |
| Completed | The Effects of Three Oral Medications on Post-operative Pain Following Endodontic Treatment NCT01178203 | Azad University of Medical Sciences | Phase 1 / Phase 2 |
| Unknown | Comparison of Mineral Trioxide Aggregate (MTA) and 20% Formocresol (FC) in Pulpotomized Human Primary Molars NCT00972556 | National Taiwan University Hospital | N/A |
| Completed | Vital Pulp Therapy to Treat Irreversible Pulpitis NCT00748280 | Shahid Beheshti University of Medical Sciences | N/A |