NCT07242742

Effectiveness of Pulpotomy vs. Root Canal Treatment in Extremely Deep Caries

Effectiveness of Pulpotomy vs. Root Canal Treatment in Extremely Deep Caries: A Randomized Controlled Trial Conducted in Supervised Undergraduate Clinics

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 93 (estimated)
• Sponsor: National University Hospital, Singapore · Academic / Other
• Sex: All
• Age: 12 Years
• Healthy volunteers: Not accepted

Summary

Recent clinical trials comparing pulpotomy versus root canal treatment (RCT) have shown promising outcomes; however, the current evidence lacks generalisability to general practitioners. It remains to be elucidated whether these favourable results can be replicated in a primary care setting. This study aims to address that gap by involving senior dental students undergoing supervised university education and training, with the potential to inform future best practice guidelines and promote the adoption of vital pulp therapy (VPT) as a predictable treatment alternative in the general dental population. The clinical procedure involves complete caries-free excavation carried out under rubber dam isolation. After confirming vital pulp status-demonstrated by bleeding upon entry, participants will be randomised to receive one of two treatments: RCT or full pulpotomy. Outcomes will include clinical and radiographic success or failure of the intervention at 12 months. Additionally, patient-reported outcomes will be collected, specifically pain experienced and the use of analgesia during the immediate post-operative period (days 3 and 7).

Conditions

• Extremely Deep Caries
• Pulpitis

Interventions

Type	Name	Description
PROCEDURE	Full Pulpotomy	Preservation of vital pulp tissue for tooth survival.
PROCEDURE	root canal treatment and intracanal medicament	Root canal treatment as a comparator to pulpotomy.

Timeline

• Start date: 2025-07-16
• Primary completion: 2027-07-01
• Completion: 2027-07-01
• First posted: 2025-11-21
• Last updated: 2025-11-21

Locations

1 site across 1 country: Singapore