NCT02819648

Oral Glucocorticoids Effect on Post Endodontic Pain

The Effect of Preoperative Oral Administration of Prednisolone on Postoperative Pain in Patients With Symptomatic Irreversible Pulpitis: A Single Center Randomized Controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 400 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The aim of this single-center randomized, double-blind, placebo-controlled clinical trial is to assess the effect of preoperative, single, oral dose of prednisolone on postoperative pain and medication intake in patients with symptomatic, irreversible pulpitis in mandibular molars.

Detailed description

Patients receive 40 mg prednisolone (two tablets Prednisolone 20 mg, Aventis Intercontinental, Paris, France); and group B (Control), where patients received two placebo tablets. All patients receive the assigned premedication 30 minutes before the administration of local anesthesia

Conditions

• Pulpitis

Interventions

Type	Name	Description
DRUG	Prednisolone	40 mg prednisolone (two tablets Prednisolone 20 mg, Aventis Intercontinental, Paris, France)
OTHER	Control	Milk Tablet

Timeline

• Start date: 2012-06-01
• Primary completion: 2016-01-01
• Completion: 2016-06-01
• First posted: 2016-06-30
• Last updated: 2016-06-30

Locations

1 site across 1 country: Egypt