| Not Yet Recruiting | RESET-MS: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Multiple Sclerosis NCT07006805 | Cabaletta Bio | Phase 1 / Phase 2 |
| Recruiting | A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489 as Add-on Therap NCT07282574 | Hoffmann-La Roche | Phase 2 |
| Recruiting | Bringing the Outdoors In: Virtual Nature Walks for Depression in Multiple Sclerosis (MS) Patients NCT07392879 | University of Michigan | N/A |
| Recruiting | Obe-cel in Refractory Progressive Forms of Multiple Sclerosis NCT07139743 | Autolus Limited | Phase 1 |
| Recruiting | Open-label, Multi-center, Phase I/II Study to Assess Safety, Disease Progression and Cellular Kinetics Followi NCT06675864 | Novartis Pharmaceuticals | Phase 1 / Phase 2 |
| Active Not Recruiting | ABA-101 in Participants With Progressive Multiple Sclerosis NCT06566261 | Abata Therapeutics | Phase 1 |
| Not Yet Recruiting | Telerehabilitation in Progressive Multiple Sclerosis NCT06485115 | Universita di Verona | N/A |
| Active Not Recruiting | A Study of KYV-101, a CD19 CAR T Cell Therapy, in Participants With Treatment Refractory Progressive Multiple NCT06451159 | Bruce Cree | Phase 1 |
| Enrolling By Invitation | Study of Circadian Focused Light Therapy in Progressive Multiple Sclerosis NCT06261528 | University of Texas Southwestern Medical Center | Phase 1 |
| Recruiting | Effects of Transcranial Static Magnetic Field Stimulation (tSMS) in Progressive Multiple Sclerosis NCT05811013 | Neuromed IRCCS | N/A |
| Recruiting | Nicotinamide Riboside Supplementation In Progressive Multiple Sclerosis NCT05740722 | Haukeland University Hospital | Phase 2 |
| Unknown | Osmotin Plant Protein for Progressive Multiple Sclerosis NCT05937802 | Ospedale Policlinico San Martino | N/A |
| Active Not Recruiting | Masitinib in the Treatment of Patients With Primary Progressive or Non-active Secondary Progressive Multiple S NCT05441488 | AB Science | Phase 3 |
| Enrolling By Invitation | Visual Processing Speed and Objective Analysis of Ocular Movements in Multiple Sclerosis NCT05706220 | Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA | — |
| Unknown | Multiple Sclerosis Prediction and Monitoring of Progression Study NCT05685784 | University Hospital, Ghent | N/A |
| Active Not Recruiting | Study of Mesenchymal Autologous Stem Cells as Regenerative Treatment for Multiple Sclerosis NCT04749667 | Haukeland University Hospital | Phase 1 / Phase 2 |
| Active Not Recruiting | ChariotMS - Cladribine to Halt Deterioration in People With Advanced Multiple Sclerosis NCT04695080 | Queen Mary University of London | Phase 2 / Phase 3 |
| Completed | Effect of Variance on Error Correction During Coupling NCT04856384 | Hasselt University | N/A |
| Completed | Identification of Retinal Perivascular Inflammation in Patients With Multiple Sclerosis Using Adaptive Optics NCT04289909 | Institut National de la Santé Et de la Recherche Médicale, France | N/A |
| Completed | Serum Neurofilaments and GFAP in Atypical Multiple Sclerosis NCT04201470 | University Hospital, Montpellier | N/A |
| Completed | Efficacy of Early Harvest Olive Oil in Cognition of Primary (PPMS) or Secondary (SPMS) Progressive Multiple Sc NCT04120675 | Aristotle University Of Thessaloniki | N/A |
| Completed | A Trial of Bile Acid Supplementation in Patients With Multiple Sclerosis NCT03423121 | Johns Hopkins University | Phase 1 / Phase 2 |
| Completed | Comparing Tolerability and Absorption of Racemic and R-lipoic Acid in Progressive Multiple Sclerosis NCT03493841 | Rebecca Spain | Phase 1 |
| Unknown | Evaluation of the Incidence of Relapses in Patients With Biotin-treated Progressive Multiple Sclerosis NCT03552211 | University Hospital, Clermont-Ferrand | — |
| Completed | Neural Stem Cell Transplantation in Multiple Sclerosis Patients NCT03269071 | IRCCS San Raffaele | Phase 1 |
| Completed | G-EO Gait Rehabilitation Training in Progressive Multiple Sclerosis NCT03980145 | Indiana University | N/A |
| Completed | A Single Ascending Dose Study of GZ402668 in Patients With Progressive Multiple Sclerosis NCT02977533 | Sanofi | Phase 1 |
| Completed | A Study of Oxidative Pathways in MS Fatigue NCT02804594 | University of California, San Francisco | Phase 2 |
| Completed | Study to Assess Effect and Safety of High Dose of Biotin (Qizenday®) in Progressive Multiple Sclerosis NCT03302806 | Nantes University Hospital | — |
| Completed | A Study to Characterize Subcutaneous or Intravenous Alemtuzumab in Patients With Progressive Multiple Sclerosi NCT02583594 | Genzyme, a Sanofi Company | Phase 1 |
| Completed | Access, Use and Opinions of Physiotherapy and Rehabilitation Services of People With Progressive MS in the UK. NCT02559765 | University of Glasgow | — |
| Completed | A Long-term Follow-up Study Of Multiple Sclerosis Patients Who Participated In Genzyme-sponsored Studies of GZ NCT02313285 | Genzyme, a Sanofi Company | — |
| Completed | A First-in-human, Single Ascending Dose Study of GZ402668 in Patients With Progressive Multiple Sclerosis NCT02282826 | Genzyme, a Sanofi Company | Phase 1 |
| Terminated | Study by Magnetic Resonance Imaging in the Progressive Forms of Multiple Sclerosis NCT02580669 | University Hospital, Montpellier | N/A |
| Unknown | Assessment of Bone Marrow-derived Cellular Therapy in Progressive Multiple Sclerosis (ACTiMuS) NCT01815632 | North Bristol NHS Trust | Phase 2 |
| Completed | Cyclic Oral Methylprednisolone Trial in Multiple Sclerosis NCT01305837 | Rigshospitalet, Denmark | Phase 2 |
| Unknown | Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Progressive Multiple Scl NCT01364246 | Shenzhen Beike Bio-Technology Co., Ltd. | Phase 1 / Phase 2 |
| Completed | Intrathecal Therapy With Monoclonal Antibodies in Progressive Multiple Sclerosis NCT01719159 | Anders Svenningsson | Phase 2 |