NCT02580669

Study by Magnetic Resonance Imaging in the Progressive Forms of Multiple Sclerosis

Study by Magnetic Resonance Imaging of the Modifications of the Vasoreactivity and Cerebral Connectivity in the Progressive Forms of Multiple Sclerosis

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: University Hospital, Montpellier · Academic / Other
• Sex: All
• Age: 30 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The goal of this study is to show pattern differences of vasoreactivity and connectivity between Progressive Multiple Sclerosis and Relapsing Remitting Multiple Sclerosis, by the use of methods of advanced brain MRIs and the Diffusion Tensor Imaging , and correlate these differences with Clinical disability and cognitive disorder results.

Detailed description

The goal of this study is to show pattern differences of vasoreactivity and connectivity between Progressive Multiple Sclerosis and Relapsing Remitting Multiple Sclerosis, by the use of methods of advanced brain MRIs, and correlate these differences with Clinical disability and cognitive disorder results. The modification of the Diffusion Tensor Imaging are well known in these two groups, as well as their link with the occurrence of movement and cognitive disorder. The study of the vasoreactivity during MRI aims to confront our results to the available data sources.

Conditions

• Progressive Multiple Sclerosis
• Multiple Sclerosis, Relapsing-Remitting

Interventions

Type	Name	Description
OTHER	Neuropsychological assessment	A neuropsychological assessment is done
OTHER	Neurologic consultation	A neurologic consultation is done
OTHER	MRIs (with vasoreactivity testing)	MRIs (with vasoreactivity testing) is done

Timeline

• Start date: 2014-06-16
• Primary completion: 2017-02-13
• Completion: 2017-02-13
• First posted: 2015-10-20
• Last updated: 2021-05-18

Locations

1 site across 1 country: France