Clinical Trials Directory

Trials / Conditions / Progressive Multifocal Leukoencephalopathy

Progressive Multifocal Leukoencephalopathy

17 registered clinical trials studyying Progressive Multifocal Leukoencephalopathy — 5 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingIntravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot
NCT07511049
National Institute of Neurological Disorders and Stroke (NINDS)Phase 2
Not Yet RecruitingPembrolizumab in Progressive Multifocal Leukoencephalopathy (PML) in Immunocompromised Patients Without HIV In
NCT06276504
Assistance Publique - Hôpitaux de ParisPhase 2 / Phase 3
RecruitingCentral Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal
NCT05849467
National Institute of Neurological Disorders and Stroke (NINDS)Phase 1
RecruitingObservational Cohort Study of Chronic Viral Infection in the Central Nervous System
NCT07512518
Peking Union Medical College Hospital—
UnknownA Phase 2 Study Evaluating JCPyV-specific T Cell Therapy for PML
NCT05541549
Cellevolve Bio IncPhase 2
CompletedNT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patien
NCT04781309
National Institute of Neurological Disorders and Stroke (NINDS)EARLY_Phase 1
CompletedDynamics of T Cell Expression of Immune Checkpoint Molecules in Progressive Multifocal Leukoencephalopathy
NCT04453917
University Hospital, ToulouseN/A
UnknownTreatment of PD-1 Inhibitor in AIDS-associated PML
NCT04091932
First Affiliated Hospital of Zhejiang UniversityPhase 2
CompletedTysabri Observational Cohort Study - Multiple Sclerosis (MS) Registries
NCT03399981
Biogen—
CompletedAdoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy With Ex Vivo Generated Polyomav
NCT02694783
National Institute of Neurological Disorders and Stroke (NINDS)EARLY_Phase 1
RecruitingNatural History Study of Progressive Multifocal Leukoencephalopathy (PML)
NCT01730131
National Institute of Neurological Disorders and Stroke (NINDS)—
TerminatedGenetic Evaluation of Natalizumab-Treated Patients With Progressive Multifocal Leukoencephalopathy
NCT01211639
Biogen—
CompletedJC Virus Reactivation in Multiple Sclerosis
NCT02004444
Beth Israel Deaconess Medical Center—
TerminatedStudy to Explore the Effect of Mefloquine in Participants With Progressive Multifocal Leukoencephalopathy (PML
NCT00746941
BiogenPhase 1 / Phase 2
CompletedRetrospective Study of the Survival of Patients Suffering From Hiv-related Progressive Multifocal Leukoencepha
NCT02895581
Fondation Ophtalmologique Adolphe de Rothschild—
CompletedRole of Inflammation in Progressive Multifocal Leukoencephalopathy (PML)
NCT01132053
Beth Israel Deaconess Medical Center—
CompletedObservational Study on Characteristics and Survival Correlates of Progressive Multifocal Leukoencephalopathy (
NCT06594614
Scientific Institute San Raffaele—