| Not Yet Recruiting | Behavior Therapy vs Education for Persistent Headache After Mild TBI NCT07229391 | VA Office of Research and Development | N/A |
| Not Yet Recruiting | Hypersensitivity to Amylin in Post-Traumatic Headache NCT07340775 | Danish Headache Center | N/A |
| Not Yet Recruiting | Eary Infusion of Eptinezumab for TreatmEnt of ACute Post-Traumatic Headaches (ELITE-ACT) NCT07191145 | Sunnybrook Health Sciences Centre | Phase 3 |
| Recruiting | Symptom Exacerbation Following Mental Imagery in Patients With Persistent Post-Concussive Symptoms NCT07166536 | Reuth Rehabilitation Hospital | N/A |
| Not Yet Recruiting | SPINEPASS: SPINE Self-management Techniques for Persistent Headache After Concussion: Physical Therapy Targeti NCT06882239 | The University of Queensland | N/A |
| Recruiting | Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 1 NCT06069791 | Yale University | Phase 1 |
| Active Not Recruiting | e-CBT DTx for Post Traumatic Headaches in Adults With History of TBI NCT06669780 | Henry M. Jackson Foundation for the Advancement of Military Medicine | N/A |
| Active Not Recruiting | GAIN Symptoms: Post-traumatic Headache NCT05857761 | University of Aarhus | N/A |
| Unknown | Hypersensitivity to Phosphodiesterase 5 Inhibition in Post-Traumatic Headache NCT05669885 | Danish Headache Center | N/A |
| Completed | Digital Solutions for Concussion NCT05635656 | St. Olavs Hospital | N/A |
| Recruiting | Exercise in Postconcussion Symptoms and Posttraumatic Headache NCT06015451 | St. Olavs Hospital | N/A |
| Unknown | Hypersensitivity to Phosphodiesterase 3 Inhibition in Post-Traumatic Headache NCT05595993 | Danish Headache Center | N/A |
| Unknown | Hypersensitivity to Opening of BKCa Channels in Post-Traumatic Headache NCT05378074 | Danish Headache Center | N/A |
| Unknown | Hypersensitivity to PACAP-38 in Post-Traumatic Headache NCT05378061 | Danish Headache Center | N/A |
| Completed | Hypersensitivity to Opening of ATP-Sensitive Potassium Channels in Post-Traumatic Headache NCT05243953 | Danish Headache Center | N/A |
| Unknown | Assessment of the Efficacy of the Transnasal Sphenopalatine Ganglion Block in the Treatment of Chronic Daily H NCT05213065 | Pablo Ingelmo | N/A |
| Recruiting | Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms NCT05414708 | Walter Reed National Military Medical Center | N/A |
| Terminated | Interactive CBT for Headache And Relaxation Training NCT05093556 | VA Connecticut Healthcare System | N/A |
| Completed | Art Therapy QEEG Study for Service Members with a Traumatic Brain Injury and Posttraumatic Stress Symptoms NCT04776304 | Walter Reed National Military Medical Center | N/A |
| Completed | Post-traumatic Headache Multidisciplinary Study NCT05328635 | Danish Headache Center | — |
| Completed | Dexamethasone for Post Traumatic Headache NCT04799015 | Montefiore Medical Center | Phase 4 |
| Completed | Multidisciplinary Translational Approach to Investigate Mechanisms Predictors & Prevention of Persistent PTH NCT04098250 | Mayo Clinic | Phase 2 |
| Recruiting | Acceptance and Commitment Therapy-based Rehabilitation of Post-concussion Symptoms NCT04614922 | St. Olavs Hospital | N/A |
| Completed | Investigate the Mechanisms, Predictors, and Prevention of Persistent Post-Traumatic Headache NCT04369729 | Mayo Clinic | — |
| Completed | The Effect of Galcanezumab-gnlm on Post-Traumatic, Migrainous Headaches NCT06901518 | Albany Medical College | Phase 4 |
| Terminated | Acupuncture for Headache Post-Traumatic Brain Injury: A Feasibility Study NCT04216173 | University of Washington | N/A |
| Withdrawn | Study of Gammacore Sapphire for the Acute and Preventive Treatment of Post-Traumatic Headache (GAP-PTH) NCT04071743 | University of Texas Southwestern Medical Center | N/A |
| Unknown | Theta Burst Stimulation for Headaches After Traumatic Brain Injury NCT04906603 | Minneapolis Veterans Affairs Medical Center | N/A |
| Completed | A Study to Evaluate Biomarker Signature to Predict the Persistence of Post-traumatic Headache NCT06132529 | Mayo Clinic | — |
| Completed | Efficacy and Tolerability of Erenumab in the Prophylactic Treatment of Persistent Post-Traumatic Headache NCT03974360 | Danish Headache Center | Phase 2 |
| Terminated | Effects of Psilocybin in Concussion Headache NCT03806985 | Yale University | Phase 1 |
| Unknown | Aerobic Exercise and Transcranial Low Laser Therapy in Patients With Central Nervous System Injury NCT03751306 | Universidade do Vale do Paraíba | N/A |
| Completed | Aerobic Exercise and Cognitive Training Effects on Postconcussive Symptomology NCT03674398 | University of Illinois at Urbana-Champaign | N/A |
| Completed | Clinical Characteristics and Pathophysiology of Post-Traumatic Headache NCT03791515 | Danish Headache Center | N/A |
| Completed | TBI Care: Collaborative Care for Pain After Traumatic Brain Injury (TBI) NCT03523923 | University of Washington | N/A |
| Completed | A Study to Test if Fremanezumab Reduces Headache in Participants With Posttraumatic Headache (PTH) NCT03347188 | Teva Branded Pharmaceutical Products R&D, Inc. | Phase 2 |
| Completed | Metoclopramide for Post Traumatic Headache NCT03220958 | Montefiore Medical Center | Phase 3 |
| Completed | rTMS Treatment of Persistent Headache and Post Concussion Symptoms Attributed to Mild Traumatic Injury to the NCT03691272 | University of Calgary | Phase 1 / Phase 2 |
| Completed | Metoclopramide for Post-Traumatic Headache. A Pilot Study NCT03056352 | Montefiore Medical Center | Phase 1 / Phase 2 |
| Completed | Prazosin for Post-Concussive Headaches NCT02965027 | Seattle Institute for Biomedical and Clinical Research | Phase 4 |
| Completed | The Role of Osteopathic Manipulation in the the Management of Post-traumatic Migraine NCT03588364 | University of California, San Diego | N/A |
| Completed | Cognitive-Behavior Therapy for Posttraumatic Headache NCT02419131 | The University of Texas Health Science Center at San Antonio | N/A |
| Terminated | Yoga Training for Returning Veterans With Headache NCT01993069 | University of California, Los Angeles | N/A |
| Unknown | Brain Biomarkers w/Mind-Body Tx in Veterans With Post Traumatic Headache (PTH) NCT02145117 | University of California, Los Angeles | N/A |
| Completed | Abobotulinumtoxina Efficacy in Post-Traumatic Headache NCT03928496 | VA Greater Los Angeles Healthcare System | Phase 4 |
| Completed | Sumatriptan as Treatment for Post-traumatic Headache NCT01854385 | University of Washington | Phase 2 |
| Completed | Amitriptyline to Prevent Headache After Traumatic Brain Injury NCT01856270 | University of Washington | Phase 2 |
| Completed | Titrated Versus High and Low Dose Nebulized Morphine to Reduce Pain in Emergency Settings NCT02200185 | University of Monastir | N/A |
| Terminated | Treximet for Prevention of Post Traumatic Headache Associated With Cognitive Dysfunction NCT01053507 | Cady, Roger, M.D. | Phase 4 |
| Terminated | Naratriptan for the Treatment of Post Traumatic Headache Associated With Cognitive Dysfunction NCT00487578 | Cady, Roger, M.D. | Phase 4 |
| Unknown | Galantamine in the Treatment of Post-Traumatic Headache NCT00219869 | Rapoport, Alan, M.D. | Phase 4 |