Clinical Trials Directory

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UnknownNCT05378074

Hypersensitivity to Opening of BKCa Channels in Post-Traumatic Headache

Hypersensitivity to Opening of BKCa Channels in Post-Traumatic Headache: A Randomized Clinical Trial

Status
Unknown
Phase
N/A
Study type
Interventional
Enrollment
21 (estimated)
Sponsor
Danish Headache Center · Academic / Other
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

The aim is to investigate whether opening of large conductance calcium-activated potassium (BKCa) channels induces headache with migraine-like features in people with persistent post-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI).

Conditions

Interventions

TypeNameDescription
DRUGMaxipostStudy participants will be allocated to receive continuous intravenous infusion of 0.05 mg/min MaxiPost.
DRUGPlaceboStudy participants will be allocated to receive continuous intravenous infusion of 20 mL placebo (isotonic saline).

Timeline

Start date
2022-09-01
Primary completion
2023-12-31
Completion
2023-12-31
First posted
2022-05-17
Last updated
2022-09-02

Locations

1 site across 1 country: Denmark

Source: ClinicalTrials.gov record NCT05378074. Inclusion in this directory is not an endorsement.