| Completed | Randomised Controlled Trial of an Antioxidant and Sunscreen Combination Cream for Reducing DNA Damage in Human NCT07301515 | Klira Skin | N/A |
| Not Yet Recruiting | Platelet Rich Fibrin Versus Platelet Rich Plasma for Microneedling Treatment of Facial Photoaging NCT06452667 | Chang Gung Memorial Hospital | N/A |
| Recruiting | Investigating Age Dependence of Fibroblast and Extracellular Matrix Responses to Cross-linked Hyaluronic Acid NCT06195605 | University of Michigan | N/A |
| Completed | Evaluation of the Effects of a Biostimulator and Dermal Fillers for Cheek Augmentation and Contour Deficiencie NCT06351358 | Galderma R&D | N/A |
| Recruiting | RFMN in Combination With 1927 nm Thulium Laser for Treating Photoaged Skin NCT06029725 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Unknown | Effects of an Oral Herbal Supplement on Skin Aging, Hydration, and Elasticity NCT06146140 | Integrative Skin Science and Research | N/A |
| Completed | A 56-day Clinical Study on Facial Skin Rejuvenation NCT06188338 | Botanee Group Co., Ltd. | N/A |
| Completed | Trial Evaluating Both Tolerability and Improvement for Signs of Facial Photoaging, Discoloration, and Texture NCT06090071 | Austin Institute for Clinical Research | Phase 4 |
| Unknown | The Effects of Zinc Di-(Dibutyryl Lisinate) on Skin Health and the Skin Microbiome in Photoaged Skin NCT06096649 | Integrative Skin Science and Research | N/A |
| Completed | Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional NCT06366503 | Revision Skincare | N/A |
| Unknown | Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and Elasticity NCT05882084 | Integrative Skin Science and Research | N/A |
| Terminated | RECELL to Promote Healing Following Carbon Dioxide (CO2) Laser Treatment in Cosmetic Patients NCT05386368 | Wake Forest University Health Sciences | Phase 4 |
| Completed | TCA 15% Chemical Peel for Improvement in Hand Lentigines NCT05471947 | Main Line Center for Laser Surgery | Phase 4 |
| Unknown | Safety and Efficacy Evaluation of the Mosaic Ultra Device NCT06117293 | CynosureLutronic | N/A |
| Completed | Effects of Stabilized Retinaldehyde on Aging Skin: A Split-Face Study NCT07510165 | Medical University of Silesia | N/A |
| Completed | Double-Blind Study Determining the Efficacy of CannaXR in Decreasing UVA Premutagenic and Photoaging Markers NCT05279495 | MINO Labs, LLC | N/A |
| Completed | A Twelve Week Clinical Study to Evaluate the Efficacy and Tolerability of a Sunscreen Moisturizer SPF 50+ NCT06148558 | Revision Skincare | N/A |
| Unknown | The Effects of a Longevity Supplement on Aging and Photoaging NCT05262036 | Integrative Skin Science and Research | N/A |
| Completed | Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Radiofre NCT06157853 | Revision Skincare | N/A |
| Completed | Clinical Study To Evaluate Paired Treatment With An Alexandrite Laser And Radiofrequency Microneedling For Fac NCT05388604 | Cynosure, Inc. | N/A |
| Completed | An Exploratory Investigation of a Novel Skincare Regimen NCT05517720 | Trophy Skin | N/A |
| Completed | Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Hybrid-F NCT06436261 | Revision Skincare | N/A |
| Completed | Same-Day Combination of VI Peel and Botox for Correction of Sun Damage, Fine Lines and Wrinkles NCT05162300 | Vitality Institute Medical Products | Phase 4 |
| Completed | Safety and Effectiveness of the CLEAR + BRILLIANT TOUCH(R) Diode Laser 1440-nm and 1927-nm Combination Wavelen NCT05027282 | Bausch Health Americas, Inc. | N/A |
| Completed | Comparative Study of a 1064-nm Fractional Picosecond Laser Versus IPL in Facial Rejuvenation NCT07122310 | Huashan Hospital | N/A |
| Completed | A Clinical Study to Evaluate the Long-Term Efficacy and Tolerability of a Daily Anti-Aging Daily Serum NCT05514782 | Revision Skincare | N/A |
| Unknown | Effectivity of 1 Finger Tip Unit Compared to 2 Finger Tip Units 0.05% Tretinoin Cream NCT05004909 | Dr.dr.Irma Bernadette, SpKK (K) | N/A |
| Completed | Xeomin, Radiesse, and Belotero Facial/Neck Rejuvenational NCT05039723 | Main Line Center for Laser Surgery | Phase 4 |
| Unknown | Effects of Dietary Soy Protein on Facial Wrinkles in Postmenopausal Women NCT04871750 | Integrative Skin Science and Research | N/A |
| Unknown | Effects of Mango Intake on Skin Health and Gut Microbiome Changes in Postmenopausal Women NCT04869852 | Integrative Skin Science and Research | N/A |
| Unknown | Efficacy of Topical Antioxidants in Tretment of Photoaging NCT04835259 | Sohag University | N/A |
| Unknown | Sample Collection Study to Assess Prevalence of Gene Mutations: Establishing Population Norms NCT05079737 | DermTech | — |
| Unknown | A Clinical Trial Evaluating the Efficacy of a Skin Cream in Improving Facial Appearance and Skin Elasticity NCT04769193 | Adipeau Inc. | N/A |
| Completed | A Clinical Study to Evaluate the Efficacy of an Anti-Aging Serum NCT05271136 | Revision Skincare | N/A |
| Completed | An Open-Label Clinical Study to Evaluate the Efficacy of a Face Cream and Eye Cream NCT04911374 | Revision Skincare | N/A |
| Completed | Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment NCT05089851 | Revision Skincare | N/A |
| Completed | Effects of Shockwave Therapy Versus Radiofrequency NCT04282057 | Escola Superior de Tecnologia da Saúde do Porto | N/A |
| Completed | A Clinical Study to Evaluate Efficacy and Safety of a Cosmetic Product in the Treatment of Facial Lines NCT04545970 | Revision Skincare | N/A |
| Completed | Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging NCT04586816 | Integrative Skin Science and Research | N/A |
| Unknown | Altreno for Chest Rejuvenation NCT04096742 | Goldman, Butterwick, Fitzpatrick and Groff | Phase 4 |
| Completed | Evaluation of Hexyresorcinol vs Hydroquinone for Photoaging NCT04345094 | Sytheon Ltd. | N/A |
| Completed | Combination Versus Laser Treatment Only NCT03661697 | University of Miami | N/A |
| Unknown | Efficacy of Fractional Microneedle Radiofrequency and Fractional Erbium-Doped Glass 1,565-nm for Baggy Lower E NCT04237324 | Xijing Hospital | N/A |
| Unknown | Efficacy in Daily Use of a Novel Skin Care Product for the Treatment of Photoaged Skin NCT03144193 | University of Manchester | N/A |
| Completed | Comparison of the Cosmetic Effects of Bakuchiol and Retinol NCT03112863 | University of California, Davis | EARLY_Phase 1 |
| Completed | A Single-Center Open-Label Study of 1064 nm for Nonablative Skin Rejuvenation NCT03421691 | Cutera Inc. | N/A |
| Completed | Efficacy and Safety of Profile HaloTM Mixed Fractional Laser on Treating of Facial and Neck Photoaging. NCT03948945 | xjpfW | N/A |
| Unknown | VELOS for the Treatment of Vascular Lesions and Skin Rejuvenation NCT02468453 | Syneron Medical | N/A |
| Unknown | The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Photoaging NCT02126644 | National University Hospital, Singapore | Phase 2 |
| Completed | A Comparative Study of Adapalene Gel,0.3% Versus Tretinoin Emollient Cream, 0.05% for the Treatment of Photoag NCT01406080 | Galderma Brasil Ltda. | Phase 3 |
| Unknown | Effect of Platelet Rich Plasma on Photoaged Skin NCT01372566 | Northwestern University | Phase 1 / Phase 2 |
| Unknown | 5fluorouracil for Advanced Photoaging NCT01405144 | Federal University of São Paulo | Phase 3 |
| Completed | Photoaging Treatment With Imiquimod NCT01935310 | CES University | N/A |
| Unknown | Efficacy and Safety of Oral Isotretinoin for Cutaneous Photodamage NCT00842907 | Federal University of São Paulo | Phase 2 |
| Completed | Photodynamic Therapy (PDT) Effect on Large Surface Photodamaged Skin NCT00843323 | University of Sao Paulo | N/A |
| Completed | Adapalene Gel 0.3% Versus Tretinoin 0.05% Emollient Cream for Treatment of Photodamage NCT00647556 | Galderma R&D | Phase 3 |
| Completed | Oral Isotretinoin for Photoaging: Results of a Randomized Controlled Phase II Trial NCT00701740 | Federal University of São Paulo | Phase 2 |