NCT03112863

Comparison of the Cosmetic Effects of Bakuchiol and Retinol

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 44 (actual)
• Sponsor: University of California, Davis · Academic / Other
• Sex: All
• Age: 30 Years – 55 Years
• Healthy volunteers: Accepted

Summary

Subjects will be assigned to a retinoid cream or bakuchiol to compare the cosmetic effects. This will take place over a 12 week period.

Detailed description

Bakuchiol is a phytochemical that has demonstrated cutaneous antiageing effects when applied topically. Early studies have suggested that bakuchiol is a functional analogue of topical retinoids, as both compounds have been shown to induce similar gene expression in the skin and lead to improvement of cutaneous photodamage. No in vivo studies have compared the two compounds for efficacy and side-effects. The aim of this study is to compare the cosmetic effects of Bakuchiol to Retinol over a 12-week period.

Conditions

• Wrinkle
• Photoaging

Interventions

Type	Name	Description
DRUG	Bakuchiol	This group will receive bakuchiol
DRUG	Retinol	This group will receive retinol

Timeline

• Start date: 2017-03-24
• Primary completion: 2019-03-01
• Completion: 2019-03-01
• First posted: 2017-04-13
• Last updated: 2021-11-02
• Results posted: 2021-11-02

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study