NCT05471947

TCA 15% Chemical Peel for Improvement in Hand Lentigines

Use of TCA 15% + 3% Glycolic Acid Chemical Peel for Improvement in Hand Lentigines

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Main Line Center for Laser Surgery · Academic / Other
• Sex: All
• Age: 22 Years
• Healthy volunteers: Accepted

Summary

This study will evaluate the efficacy of the a 15% trichloroacetic acid + 3% glycolic acid peel combination for treatment of lentigines on the hands. This peel combination is sold over the counter. Patients will receive 3 treatments (spaced 4 weeks).

Detailed description

This clinical investigation is a prospective study consisting of a screening visit, 3 treatment visits, and 1 follow-up visit. Baseline and post-treatment photos will be graded and compared. A total of 20 patients will be recruited. Following informed consent and screening, subjects' dorsal hands will be photographed. Patients will receive 3 treatments with the 15% TCA + 3% glycolic acid peel every 4-6 weeks on the dorsal hands. Post-treatment, patients will be instructed to apply Aquaphor to the treated area twice daily for 5 days. Patients' hands will be photographed at each visit. Four to six weeks after their final treatment, subjects will return for photography.

Conditions

• Photoaging
• Lentigo

Interventions

Type	Name	Description
DRUG	15% Trichloroacetic acid + 3% glycolic acid	Treatment of the hand with an over-the-counter chemical peel containing 15% trichloroacetic acid + 3% glycolic acid

Timeline

• Start date: 2023-03-15
• Primary completion: 2023-12-30
• Completion: 2024-12-01
• First posted: 2022-07-25
• Last updated: 2025-03-17

Locations

1 site across 1 country: United States