NCT04586816

Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 19 (actual)
• Sponsor: Integrative Skin Science and Research · Industry
• Sex: Female
• Age: 30 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Recent research has reported that the maple leaf extract exhibits anti-aging effects by inhibiting elastase activity, thereby preventing the breakdown of elastin and interfering with the formation of wrinkles. Red maple leaf extract contains phenolic compounds known as glucitol-core-containing gallotannins (GCGs) which help reduce the appearance of wrinkles and may decrease skin inflammation, dark spots and pigmentation. The objective of this study is to examine the effects of topical Maplifa on the cosmetic appearance of facial lines, redness and skin tone.

Conditions

• Photoaging
• Hyperpigmentation
• Rhytides

Interventions

Type	Name	Description
COMBINATION_PRODUCT	1% red maple leaf extract in cream base	1% red maple leaf extract is combined in a cream base
COMBINATION_PRODUCT	5% red maple leaf extract	5% red maple leaf extract is combined in a cream base
COMBINATION_PRODUCT	vehicle	vehicle cream base only

Timeline

• Start date: 2019-09-10
• Primary completion: 2020-01-15
• Completion: 2020-01-15
• First posted: 2020-10-14
• Last updated: 2020-10-14

Locations

1 site across 1 country: United States