NCT04869852

Effects of Mango Intake on Skin Health and Gut Microbiome Changes in Postmenopausal Women

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Integrative Skin Science and Research · Industry
• Sex: Female
• Age: 50 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Mangos are a rich source of nutrients such as carotenoids, vitamin C and fiber, as well as polyphenols and phenolic acids such as mangiferin, ellagic acid, and gallotannins. Mango extract has been reported to protect against photo-aging of the skin in an animal model exposed to UVB radiation, reducing the length of wrinkles and increasing collagen bundles. Beta-carotene and other carotenoids are known to provide skin protection from sunlight, but other compounds in mangos, may also be important in reducing oxidative damage in aging skin. We have recently completed a pilot study showing a clear trend in skin wrinkle reduction when postmenopausal women consumed 85g of Ataulfo mangos, four times per week for 16 weeks. To confirm and extend these results, a larger study is proposed.

Conditions

• Photoaging

Interventions

Type	Name	Description
OTHER	Food	85g mango, 4x/week

Timeline

• Start date: 2021-05-30
• Primary completion: 2022-06-30
• Completion: 2023-06-30
• First posted: 2021-05-03
• Last updated: 2021-05-20