| Not Yet Recruiting | Safety and Efficacy of PIPAC Using Single Agent Mitomycin in Solid Tumors NCT07487168 | H. Lee Moffitt Cancer Center and Research Institute | Phase 1 |
| Recruiting | Heated Versus Aerosol-based Laparoscopic Chemotherapy for Cancer That Has Spread to the Peritoneum (Abdominal NCT07282834 | Patrick Wagner, MD, FACS | Phase 2 |
| Recruiting | Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients Wi NCT04107077 | University of Chicago | Phase 2 |
| Recruiting | Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patie NCT07001748 | ECOG-ACRIN Cancer Research Group | Phase 2 / Phase 3 |
| Recruiting | Blood Clearance Kinetics of the Nucleosome and CTCF in Peritoneal Metastasis Colorectal Cancer. NCT06929013 | Hospices Civils de Lyon | N/A |
| Recruiting | Intensification Treatment of Ovarian Cancer by PIPAC NCT07514494 | Moscow Regional Oncological Dispensary | Phase 2 |
| Recruiting | Enhanced Recovery After Surgery (ERAS) in Patients With Peritoneal Carcinomatosis Undergoing Cytoreductive Sur NCT07493876 | Fondazione del Piemonte per l'Oncologia | N/A |
| Recruiting | PhI Pilot Study Pafolacianine Inject for Intraoperative Imaging on Outcomes of GI Cancer Peritoneal Carcinomat NCT06511037 | University of California, Irvine | EARLY_Phase 1 |
| Recruiting | A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer NCT06623396 | Memorial Sloan Kettering Cancer Center | Phase 1 |
| Recruiting | Technical Feasibility of Modified Early Post-Operative Intraperitoneal Chemotherapy (mEPIC) NCT05913674 | Ciusss de L'Est de l'Île de Montréal | Phase 2 |
| Completed | Molecular Citology to Detect Free Cancer Cells in Peritoneal Fluid NCT07478107 | University of Campania Luigi Vanvitelli | — |
| Recruiting | A Study of Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Ar NCT06504147 | Oncoinvent Solutions AS | Phase 2 |
| Completed | The PIPAC-OPC7 Study: The Use of PET/CT Scans as a Method of Evaluation in Patients Treated With PIPAC, a Pilo NCT06144853 | Odense University Hospital | — |
| Recruiting | Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) and Electrostatic PIPAC (ePIPAC) With Paclitaxel In P NCT05395910 | National University Hospital, Singapore | Phase 1 |
| Recruiting | Galunisertib Combined With Capecitabine in Advanced CRC With PM NCT05700656 | The Netherlands Cancer Institute | Phase 1 / Phase 2 |
| Recruiting | Ga68-FAPI-46 PET/CT for Preoperative Assessment of Peritoneal Carcinomatosis NCT06061874 | Jules Bordet Institute | N/A |
| Recruiting | Patient Derived Vascularized MicroTumor Model of Gastrointestinal Peritoneal Carcinomatosis NCT05844865 | University of California, Irvine | N/A |
| Terminated | Near-infrared Imaging With Indocyanine Green for Detection of Peritoneal Metastases for Gastric Adenocarcinoma NCT05687617 | Laval University | Phase 2 |
| Recruiting | Response Prediction of Hyperthermic Intraperitoneal Chemotherapy in Gastro- Intestinal Cancer NCT05652348 | Technische Universität Dresden | — |
| Unknown | A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Ovarian Cancer NCT05801783 | Shanghai Yunying Medical Technology | EARLY_Phase 1 |
| Completed | PIPAC and FOLFOX for Gastric Cancer Peritoneal Cancer NCT05644249 | Vilnius University | N/A |
| Recruiting | Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointesti NCT05277766 | University Hospital, Ghent | Phase 1 |
| Active Not Recruiting | Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis From Colo NCT05185947 | National Cancer Institute (NCI) | Phase 2 |
| Active Not Recruiting | Diagnostic Value of Diffusion-weighted Magnetic Resonance in High-risk Colorectal and Appendiceal Neoplasms NCT05623787 | Laval University | N/A |
| Unknown | Intraperitoneal Chemotherapy in Gastric Cancer With Peritoneal Carcinomatosis NCT05541146 | Instituto do Cancer do Estado de São Paulo | Phase 2 |
| Terminated | Intraperitoneal Paclitaxel-loaded TPM for Treatment of Peritoneal Carcinomatosis NCT05159050 | Carlos Chan | Phase 1 |
| Completed | Diagnostic Value of DWI-MRI for Detection of Peritoneal Metastases in High-risk Pancreatic Ductal Adenocarcino NCT05340569 | Laval University | N/A |
| Recruiting | Clinical Trial on HIPEC With Mitomycin C in Colon Cancer Peritoneal Metastases (GECOP-MMC) NCT05250648 | Hospital Universitario de Fuenlabrada | Phase 4 |
| Unknown | Combined Nabpaclitaxel Pressurized IntraPeritoneal Aerosol Chemotherapy With Systemic Nabpaclitaxel-Gemcitabin NCT05371223 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Phase 2 |
| Completed | Validation Study on the Removal of EpCAM-positive Tumour Cells From Blood Collected During Tumour Surgery Usin NCT06789224 | Lindis Bloodcare GmbH | N/A |
| Completed | Bonds Between Circulating Tumoral ADN (ctDNA) and the Development of Peritoneal Carcinomatosis for Patients Un NCT04766502 | Institut de Cancérologie de Lorraine | N/A |
| Recruiting | Docetaxel, Oxaliplatin and 5-FU for Gastric Cancer With Inoperable Malignant Bowel Obstruction NCT04840264 | Sixth Affiliated Hospital, Sun Yat-sen University | Phase 2 |
| Completed | A Study to Evaluate ONM100, an Intraoperative Fluor Imaging Agent for the Detection of Peri Mets NCT04950166 | OncoNano Medicine, Inc. | Phase 2 |
| Recruiting | Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosi NCT04847063 | National Cancer Institute (NCI) | Phase 1 |
| Unknown | Second Line Oxaliplatin Based Chemotherapy Alone Versus Oxaliplatin Based PIPAC and Chemotherapy in Colorectal NCT04734691 | Sleiman Marwan-Julien | Phase 2 |
| Recruiting | Impact of Cardiac Coherence on Anxiety in Patients Operated on for a Peritoneal Carcinosis NCT04024917 | Institut du Cancer de Montpellier - Val d'Aurelle | N/A |
| Unknown | Role of Magnetic Resonance Enterography for Predicting Peritoneal Cancer Index NCT05063019 | Chang Gung Memorial Hospital | N/A |
| Recruiting | Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) Associated With Systemic Chemotherapy in Women With A NCT04811703 | Hospices Civils de Lyon | Phase 1 |
| Recruiting | Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPEC NCT04779554 | Prakash Pandalai | Phase 2 |
| Completed | Study of Safety and Efficiency of the Use of Neutral Argon Plasma in Cyto-reduction of Miliary Implants in the NCT04904042 | Maimónides Biomedical Research Institute of Córdoba | N/A |
| Unknown | Peritoneal Carcinomatosis Leveraging ctDNA Guided Treatment in GI Cancer Study (PERICLES Study) NCT04929015 | Rutgers, The State University of New Jersey | N/A |
| Completed | Changes in Coagulation in Colorectal Cancer Patients Undergoing Surgical Treatment NCT04744688 | University of Aarhus | — |
| Completed | Feasibility Study of a 4 Stage Bowel Obstruction Cancer Diet NCT04898842 | Royal Surrey County Hospital NHS Foundation Trust | N/A |
| Completed | Metachonous Peritoneal Carcinomatosis Incidence After Curative Surgery for pT4 Colon Cancer Patients NCT05300789 | Carlos Cerdán Santacruz | — |
| Unknown | Preoperative Abdominal Enhanced CT, 18F-FDG PET/CT and 68Ga-FAPI PET/CT in Peritoneal Carcinomatosis of Gastri NCT04778345 | Fujian Medical University | N/A |
| Active Not Recruiting | Study of Sequential Systemic Therapy + Intraperitoneal Paclitaxel in Gastric/GEJ Peritoneal Carcinomatosis NCT04762953 | University of California, Irvine | Phase 2 |
| Active Not Recruiting | PIPAC With Nab-paclitaxel and Cisplatin in Peritoneal Carcinomatosis NCT04000906 | University Hospital, Geneva | Phase 1 |
| Terminated | Intraperitoneal Docetaxel in Combination With mFOLFOX6 for Gastric Cancer Patients With Peritoneal Carcinomato NCT04583488 | Johns Hopkins University | Phase 1 |
| Recruiting | Complete Cytoreduction Followed by IP and Systemic Chemotherapies for Gastric Cancer With Peritoneal Carcinoma NCT04547725 | National Taiwan University Hospital | N/A |
| Suspended | Treatment of Malignant Peritoneal Mesothelioma (MESOTIP) NCT03875144 | Institut du Cancer de Montpellier - Val d'Aurelle | Phase 2 |
| Terminated | Pasireotide to Reduce Clinically Relevant Digestive Leakage After Complete Cytoreductive Surgery (CRS) Plus Hy NCT04826432 | Gustave Roussy, Cancer Campus, Grand Paris | Phase 2 |
| Unknown | Intraoperative ICG Fluorescence Imaging for Peritoneal Carcinomatosis Detection NCT04352894 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | N/A |
| Recruiting | PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorecta NCT04329494 | City of Hope Medical Center | Phase 1 |
| Unknown | Combined Neoadjuvant Systemic and PIPAC Therapy (NASPIT) for Patients With Colorectal Peritoneal Metastasis El NCT04475159 | Prof. Aviram Nissan | Phase 2 |
| Terminated | Comparison of "Roll-over' Technique With Standard Abdominal Paracentesis in Suspected Peritoneal Carcinomatosi NCT04232384 | Post Graduate Institute of Medical Education and Research, Chandigarh | N/A |
| Completed | Intraperitoneal and Intravenous Paclitaxel Chemotherapy With Oral Capecitabine for Gastric Adenocarcinoma With NCT04034251 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Study of Radspherin® in Recurrent Ovarian Cancer Subjects With Peritoneal Carcinomatosis NCT03732768 | Oncoinvent Solutions AS | Phase 1 |
| Recruiting | Oncological Benefits of Pressured Intraperitoneal Aerosol Chemotherapy (PIPAC) in Patients With T3-4 Gastric C NCT04595929 | St. Petersburg State Pavlov Medical University | N/A |
| Active Not Recruiting | Paclitaxel for the Treatment of Gastric or Gastroesophageal Cancer NCT04220827 | M.D. Anderson Cancer Center | Phase 1 |
| Unknown | A Phase II Study of Conversion Surgery After IP Paclitaxel With XELOX Chemotherapy in AGC With Peritoneal Diss NCT04797923 | Gangnam Severance Hospital | Phase 2 |
| Unknown | Dedicated MR Imaging vs Surgical Staging of Peritoneal Carcinomatosis in Colorectal Cancer NCT04231175 | The Netherlands Cancer Institute | N/A |
| Terminated | A Phase I Study Evaluating SCB-313 for the Treatment of Subjects With Peritoneal Carcinomatosis NCT04047771 | Sichuan Clover Biopharmaceuticals, Inc. | Phase 1 |
| Completed | Link of Interest and Training Model NCT04341337 | Centre de l'arthrose, Paris | — |
| Unknown | Peritoneal Carcinomatosis Extent Evaluation: Radiologic, Laparoscopic and Pathologic. NCT03798132 | Shimaa Abdalla Ahmed | — |
| Completed | Intraperitoneal Paclitaxel Plus Systemic mFOLFOX6 NCT03618758 | Seoul National University Bundang Hospital | Phase 1 / Phase 2 |
| Unknown | Multi-modality Imaging in Peritoneal Carcinomatosis of Colorectal Origin NCT03699332 | Radboud University Medical Center | Phase 1 / Phase 2 |
| Completed | Nivolumab With or Without Ipilimumab in Treating Patients With Recurrent or High Grade Gynecologic Cancer With NCT03508570 | M.D. Anderson Cancer Center | Phase 1 |
| Withdrawn | CAR-T Intraperitoneal Infusions for CEA-Expressing Adenocarcinoma Peritoneal Metastases or Malignant Ascites ( NCT03682744 | Sorrento Therapeutics, Inc. | Phase 1 |
| Completed | Intravital Microscopy (IVM) in Patients With Peritoneal Carcinomatosis (PC) NCT03517852 | Mayo Clinic | N/A |
| Completed | Clinical Pharmacology of Platinum-based Hyperthermic Intraperitoneal Chemotherapy NCT03364907 | Radboud University Medical Center | — |
| Recruiting | Adjuvant Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) in Resected High Risk Colon Cancer Patients NCT03280511 | Michael Bau Mortensen | Phase 2 |
| Completed | Role of the Peritoneal Microenvironment in the Pathogenesis and Spread of Colorectal Carcinomatosis NCT03777943 | University Hospital, Ghent | — |
| Completed | PIPAC for Peritoneal Metastases of Colorectal Cancer NCT03246321 | Koen Rovers | Phase 2 |
| Active Not Recruiting | Gastrectomy + Cytoreductive Surgery + HIPEC for Gastric Cancer With Peritoneal Dissemination. NCT03348150 | The Netherlands Cancer Institute | Phase 3 |
| Recruiting | Surgery and Heated Intraperitoneal Chemotherapy for Adrenocortical Carcinoma NCT03127774 | Columbia University | Phase 2 |
| Completed | PIPAC Nab-pac for Stomach, Pancreas, Breast and Ovarian Cancer NCT03304210 | University Hospital, Ghent | Phase 1 |
| Active Not Recruiting | Feasibility and Safety of IMP321 (Eftilagimod Alpha) for Advanced Stage Solid Tumors NCT03252938 | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | Phase 1 |
| Terminated | Cytoreductive Surgery and Intraperitoneal Chemotherapy for Stomach CAncer: a Feasibility Study NCT03150628 | Richard van Hillegersberg | Phase 2 |
| Unknown | Efficacy of HIPEC Combined With Systemic Chemotherapy and CRS on Peritoneal Metastases From Gastric Cancer NCT03179579 | Shu-Zhong Cui | Phase 3 |
| Unknown | Pilot Study on Intra-abdominal Photodynamic Diagnosis in Peritoneal Carcinosis NCT02840331 | University Hospital Tuebingen | Phase 3 |
| Active Not Recruiting | Perioperative Systemic Therapy for Isolated Resectable Colorectal Peritoneal Metastases NCT02758951 | Koen Rovers | Phase 2 / Phase 3 |
| Active Not Recruiting | Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) With Oxaliplatin In Patients With Peritoneal Carcinom NCT03172416 | National University Hospital, Singapore | Phase 1 |
| Completed | Defining Inflammation Related to Peritoneal Carcinomatosis in Women With Ovarian or Colon Cancer. NCT04122937 | University of Pisa | — |
| Completed | Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in Peritoneal Carcinomatosis From Gastric NCT03253939 | Hospices Civils de Lyon | — |
| Terminated | Hyperthermic Intraperitoneal Chemotherapy (HIPEC) : Predictive Marker and Mechanism NCT02803515 | Centre Hospitalier Universitaire de Nice | N/A |
| Recruiting | Longitudinal Study of CRS/HIPEC for Peritoneal Carcinomatoses NCT04108936 | University of Regensburg | — |
| Completed | Heated Mitomycin and Cisplatin During Surgery in Treating Patients With Stomach or Gastroesophageal Cancer NCT02891447 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | Trial of Intraperitoneal (IP) Oxaliplatin in Combination With Intravenous FOLFIRI NCT02833753 | University of Massachusetts, Worcester | Phase 1 |
| Completed | GL-ONC1 Oncolytic Immunotherapy in Patients With Recurrent or Refractory Ovarian Cancer NCT02759588 | Genelux Corporation | Phase 1 / Phase 2 |
| Unknown | Register Study of Patients With Peritoneal Carcinomatosis Treated With PIPAC (Pressurized Intra-peritoneal Aer NCT03100708 | University of Leipzig | — |
| Completed | Study of Efficacy and Safety of Laparoscopic Intra-abdominal Chemotherapy (PIPAC) Performed in Patients With P NCT02604784 | Fondazione del Piemonte per l'Oncologia | Phase 1 / Phase 2 |
| Unknown | Prospective Intraperitoneal Chemotherapy in Carcinomatosis Cohort Study NCT03124394 | Kantonsspital Winterthur KSW | — |
| Completed | Thrombin Generation and Platelet Activation in CRS/HIPEC NCT03034850 | Ziekenhuis Oost-Limburg | — |
| Completed | Treating Peritoneal Carcinomatosis With PIPAC NCT02320448 | Michael Bau Mortensen | Phase 2 |
| Completed | Study in Patients With Peritoneal Carcinomatosis From CEA Overexpressing Digestive Cancer NCT02784028 | Institut du Cancer de Montpellier - Val d'Aurelle | N/A |
| Completed | Surgery With HIPEC in Treating Patients With a High Risk of Developing Colorectal Peritoneal Carcinomatosis NCT02179489 | Zhejiang University | N/A |
| Completed | αDC1 Vaccine + Chemokine Modulatory Regimen (CKM) as Adjuvant Treatment of Peritoneal Surface Malignancies NCT02151448 | David Bartlett | Phase 1 / Phase 2 |
| Completed | Intraperitoneal Docetaxel With Cisplatin and TS-ONE for Gastric Cancer With Peritoneal Carcinomatosis NCT02024841 | The University of Hong Kong | Phase 1 |
| Completed | Surgery and Heated Chemotherapy for Adrenocortical Carcinoma NCT01833832 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Imaging of Peritoneal Carcinomatosis From Ovarian Carcinoma Patients NCT01834469 | Jules Bordet Institute | Phase 1 / Phase 2 |
| Completed | Near-Infrared Imaging of Peritoneal Carcinomatosis From Colorectal Cancer NCT02032485 | Jules Bordet Institute | Phase 2 |
| Completed | A Nomogram to Predict Major Postoperative Complications After Cytoreductive Surgery and HIPEC Based on Pre and NCT05547568 | CHU de Reims | — |
| Completed | Preoperative Inflammatory Markers Predict Postoperative Complications After Cytoreductive Surgery and Hyperthe NCT06318793 | CHU de Reims | — |
| Terminated | Randomized Controlled Trial to Prevent Peritoneal Seeding in Gastric Cancer NCT01683864 | University Hospital Tuebingen | Phase 2 / Phase 3 |
| Completed | Role of Intraperitoneal Intraoperative Chemotherapy With Paclitaxel in the Surgical Treatment of Peritoneal Ca NCT02739698 | Maimónides Biomedical Research Institute of Córdoba | Phase 2 |
| Completed | Cytoreduction Followed by Normothermic Versus Hyperthermic Intraperitoneal Intraoperative Chemoperfusion (HIPE NCT01575730 | University Hospital, Ghent | Phase 2 |
| Recruiting | Register With Patients in Which Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) Was Performed NCT01617382 | Universitaire Ziekenhuizen KU Leuven | — |
| Completed | A Study of GL-ONC1, an Oncolytic Vaccinia Virus, in Patients With Advanced Peritoneal Carcinomatosis NCT01443260 | Genelux GmbH | Phase 1 / Phase 2 |
| Completed | Representation of the Body for Patients With Cancer NCT01560533 | Hospices Civils de Lyon | N/A |
| Completed | HIPEC for Peritoneal Carcinomatosis NCT02040142 | Albert Einstein College of Medicine | Phase 2 |
| Completed | Veliparib and Radiation Therapy in Treating Patients With Advanced Solid Malignancies With Peritoneal Carcinom NCT01264432 | National Cancer Institute (NCI) | Phase 1 |
| Suspended | Clinical Trial at Neoadjuvant Peritoneal and Systemic Chemotherapy Plus HIPEC in Gastric Carcinomatosis NCT01342653 | Hospital General Universitario Gregorio Marañon | Phase 2 |
| Terminated | Combined Anticancer Treatment of Advanced Colon Cancer NCT01540344 | University of Regensburg | Phase 2 |
| Completed | Stress Reduction in Improving Quality of Life in Patients With Recurrent Gynecologic or Breast Cancer NCT01764789 | Ohio State University Comprehensive Cancer Center | N/A |
| Terminated | Cytoreductive Surgery(CRS) Plus Hyperthermic Intraoperative Peritoneal Chemotherapy(HIPC) With Cisplatin to Tr NCT01116791 | Baki Topal | Phase 2 |
| Withdrawn | Prospective Randomized Trial Evaluating Mandatory Second Look Surgery With HIPEC and CRS vs. Standard of Care NCT01095523 | National Cancer Institute (NCI) | Phase 2 |
| Completed | FloSeal in CRS and HIPEC NCT01957852 | Maisonneuve-Rosemont Hospital | — |
| Completed | Neo-adjuvant Chemo + Peritonectomy + Hyperthermic Intraperitoneal Chemo in Peritoneal Carcinomatosis From Gast NCT01379482 | Uppsala University | Phase 2 |
| Completed | Single-photon Emission Computed Tomography (SPECT) to Predict Peritoneal Chemotherapy NCT00997633 | Uppsala University | — |