| Not Yet Recruiting | Provocation After Nurse-Directed Assessment (PANDA) Study NCT07127835 | The University of Hong Kong | — |
| Recruiting | Risk-stratified Testing for Safe Removal of Penicillin Allergy Labels NCT06755281 | Deniz Göcebe | N/A |
| Not Yet Recruiting | Evaluating the Feasibility of High-volume, Low-risk Penicillin Allergy De-labelling to Maximise Efficiency in NCT06532448 | University Hospital Southampton NHS Foundation Trust | N/A |
| Active Not Recruiting | Removal of Erroneous Penicillin Allergy Labels: Implementation Study (REPeAL) NCT06528106 | Royal Cornwall Hospitals Trust | — |
| Recruiting | Geisinger Antibiotic Allergy Pilot Program: Assess and Address NCT05464615 | Geisinger Clinic | EARLY_Phase 1 |
| Recruiting | Penicillin Allergy Delabeling After a One-Dose Versus Two-Dose Graded Direct Oral Challenge NCT06303128 | James Tarbox, MD | Phase 3 |
| Unknown | Safety and Efficacy of an Oral Penicillin Challenge in Low Risk Hospitalized Patients NCT04408508 | Saskatchewan Health Authority - Regina Area | N/A |
| Unknown | Penicillin Allergy Delabeling Among Surgical Patients NCT05956080 | University Medicine Greifswald | N/A |
| Unknown | Impact of Pre-operative Penicillin Allergy Evaluation on Surgical Prophylaxis NCT05823155 | Chinese University of Hong Kong | N/A |
| Terminated | Oral Penicillin Challenge and Allergy De-labeling in Children NCT05563610 | Phoenix Children's Hospital | Phase 4 |
| Completed | Penicillin De-labeling in the Pediatric Primary Care Setting NCT05010304 | University of Texas Southwestern Medical Center | Phase 4 |
| Active Not Recruiting | A Study of the Impact of Penicillin Allergy on Antimicrobial Resistance and ouTcomes NCT07177690 | University of Leeds | — |
| Completed | Inpatient Penicillin Allergy Delabeling Study NCT05020327 | University Hospitals Cleveland Medical Center | Phase 4 |
| Completed | Penicillin Allergy Delabeling Project NCT05090527 | Haukeland University Hospital | N/A |
| Completed | Penicillin Allergy Testing in STD Clinics NCT04620746 | Johns Hopkins University | Phase 4 |
| Completed | The Effect of Providing Stratification of Low Risk Penicillin Allergies on Penicillin Allergy Label Removal NCT03702270 | Vanderbilt University Medical Center | N/A |
| Completed | Feasibility Assessment of Risk Stratification and Oral Challenge in Hospitalized Children at Low Risk for Anti NCT04441021 | Vanderbilt University Medical Center | — |
| Completed | Effect of Providing Stratification of Low Risk Penicillin Allergies on Penicillin Allergy Label Removal in ICU NCT03702283 | Vanderbilt University Medical Center | N/A |
| Completed | Penicillin Allergy Testing and Resensitization Rate NCT03942731 | Centre Hospitalier Régional Metz-Thionville | — |
| Unknown | Amoxicillin Challenge for Penicillin Allergy Diagnosis NCT03757052 | CHU de Quebec-Universite Laval | N/A |
| Unknown | Penicillin Allergy in Shfayim Clinic NCT03499457 | Clalit Health Services | N/A |
| Completed | Oral Challenge in the Pediatric ED NCT03404804 | Medical College of Wisconsin | Phase 4 |
| Completed | Beta-lactam Pharmacokinetics in Secondary Care NCT03033394 | Imperial College London | — |
| Unknown | The Frequency of Positive Challenge Test to Penicillin in Children Suspected to Have Allergy to Penicillin NCT02702349 | Hillel Yaffe Medical Center | N/A |
| Completed | Drug Challenges Without Prior Skin Testing NCT03158831 | Montefiore Medical Center | Phase 1 |
| Completed | Perioperative Antibiotic Choices for Surgical Prophylaxis in Penicillin-allergic Pediatric Patients NCT02036840 | Joseph D. Tobias | — |
| Completed | The Diagnosis of Beta-lactam Hypersensitivity in Thailand NCT01667055 | Chulalongkorn University | — |
| Completed | Penicillin Skin Testing in Patients With History of Allergic Reactions to Betalactams NCT00789217 | Chulalongkorn University | N/A |
| Withdrawn | Equivalency of Penicilloate Skin Test Reactivity Prepared by a Modified Alkaline Hydrolysis Technique NCT00589251 | Mayo Clinic | N/A |
| Terminated | Treating Patients With a History of Non-Life Threatening Allergic Reaction to Penicillin With Penicillin NCT00363688 | Meir Medical Center | Phase 4 |