NCT05563610

Oral Penicillin Challenge and Allergy De-labeling in Children

Oral Penicillin Challenge and Allergy De-labeling in the Phoenix Children's Hospital Emergency Department

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 31 (actual)
• Sponsor: Phoenix Children's Hospital · Academic / Other
• Sex: All
• Age: 2 Years – 17 Years
• Healthy volunteers: Not accepted

Summary

The primary purpose of this study is to investigate the portion of penicillin allergy labels that are not true allergies using oral amoxicillin challenges among pediatric patients. The secondary purpose is to evaluate the safety and feasibility of administering oral penicillin allergy challenges in the Pediatric Emergency Department.

Conditions

• Penicillin Allergy

Interventions

Type	Name	Description
DRUG	Amoxicillin 500mg	Patients screened to be low risk of penicillin allergy will be randomized to receive amoxicillin dose or not

Timeline

• Start date: 2022-09-26
• Primary completion: 2024-06-12
• Completion: 2024-06-12
• First posted: 2022-10-03
• Last updated: 2024-06-14

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study