| Recruiting | Trial of Oligometastasis SBRT With Immediate, Simulation-Free Treatment Delivery (OLIGO-SWIFT) NCT07079098 | Case Comprehensive Cancer Center | Phase 1 |
| Not Yet Recruiting | 125I Seed Implantation Plus Systemic Therapy for Oligoprogressive NSCLC or Colorectal Cancer NCT07333651 | Li Min | Phase 2 |
| Recruiting | Stereotactic Radiotherapy Versus Palliative Conventional Radiotherapy for Oligoprogressive Metastatic Cancers NCT06918951 | British Columbia Cancer Agency | N/A |
| Suspended | Systemic Therapy in Combination with Stereotactic Radiotherapy in Patients with Metastatic Colorectal Cancer U NCT05375708 | UMC Utrecht | Phase 2 |
| Recruiting | Real-Time Atherosclerosis Activity After Thoracic Radiotherapy Using Sodium Fluoride Positron Emission Tomogra NCT06373497 | Katelyn Atkins | EARLY_Phase 1 |
| Recruiting | Chemoimmunotherapy Followed by Surgery for Oligometastatic Esophagogastric Cancer: (TORO Protocol) NCT06668454 | University Health Network, Toronto | N/A |
| Recruiting | Single vs. Multiple Fraction Trial of Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligom NCT05784428 | Robert Olson | N/A |
| Recruiting | OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction NCT06462963 | European Organisation for Research and Treatment of Cancer - EORTC | N/A |
| Not Yet Recruiting | Feasibility Trial of Darwin OncoTreat and OncoTarget Precision Medicine Testing NCT06842030 | Good Samaritan Hospital Medical Center, New York | N/A |
| Recruiting | Niraparib Rechallenge After Surgery in Ovarian Cancer Patients With Oligometastatic Progression NCT06180356 | MedSIR | Phase 2 |
| Recruiting | Lymphocyte Support to SBRT in Patients With Oligo-metastatic Solid Cancer NCT06439888 | Gustave Roussy, Cancer Campus, Grand Paris | Phase 1 / Phase 2 |
| Recruiting | Stereotactic Radiotherapy for Oligometastasis (1-5) in Various Tumor Sites vs. Palliative Care NCT06556550 | National Medical Research Radiological Centre of the Ministry of Health of Russia | Phase 2 / Phase 3 |
| Not Yet Recruiting | Outcomes of Local Treatment for Oligometastatic Prostate Cancer Diagnosed Using PSMA PET Imaging: OLIGOMET Stu NCT06430411 | Medical University of Vienna | — |
| Terminated | Surgical Resection of Synchronous Pulmonary or Hepatic Oligometastatic Pancreatic Ductal Adenocarcinoma NCT06122480 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | N/A |
| Recruiting | High-Risk Metachronous Oligometastatic Prostate Cancer Trial NCT06212583 | University of Maryland, Baltimore | Phase 2 |
| Recruiting | Longitudinal Study of Local Ablative Therapy in Oligometastatic Disease NCT06356779 | Gitte Fredberg Persson MD PhD | N/A |
| Terminated | Study of PULSAR-ICI +/- IMSA101 in Patients With Oligometastatic NSCLC and RCC NCT05846646 | ImmuneSensor Therapeutics Inc. | Phase 2 |
| Recruiting | Prospective Observational Basket Study of Stereotactic Body Radiation Therapy for OligoMetastatic Patients Fro NCT05903261 | Istituto Clinico Humanitas | — |
| Recruiting | Phase 2 Study of SBRT Plus Tislelizumab and Regorafenib in Unresectable or Oligometastatic HCC NCT05917431 | Peking University Cancer Hospital & Institute | Phase 2 |
| Unknown | Prediction of True Oligo-metastatic Disease. NCT05806151 | National Cancer Institute, Naples | — |
| Recruiting | Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cance NCT06121700 | Fudan University | Phase 2 |
| Unknown | Anti-PD-1 Immunotherapy Combined With SBRT for Patients With Oligometastatic ESCC NCT05626569 | Sun Yat-sen University | Phase 2 |
| Recruiting | Ablative Radiosurgery vs Stereotactic RT in 5 Fractions With SIB for Oligometastatic Bone Lesions NCT05679427 | IRCCS San Raffaele | N/A |
| Active Not Recruiting | Additional Consolidative Esophagectomy for the Patients With Oligometastatic Resectable ESCC NCT05951127 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | N/A |
| Recruiting | TERPS Trial for de Novo Oligometastic Prostate Cancer NCT05223803 | University of Maryland, Baltimore | Phase 2 |
| Recruiting | Local Therapy for Oligometastatic ESCC Patients Treated With PD-1 Inhibitor NCT06190782 | Fudan University | Phase 3 |
| Recruiting | Stereotactic Ablative Radiotherapy for OligoMetastatic Breast Cancer NCT05377047 | Vastra Gotaland Region | N/A |
| Unknown | Stereotactic Radiation Therapy for HE2-positive Oligometastatic Breast Cancer NCT06299852 | N.N. Petrov National Medical Research Center of Oncology | N/A |
| Unknown | Liquid Biopsy in Advanced Oligometastatic NSCLC Receiving Surgery NCT05648370 | Guangdong Provincial People's Hospital | — |
| Recruiting | Metastasis-directed Therapy for Oligorecurrent Prostate Cancer NCT05352178 | Universitaire Ziekenhuizen KU Leuven | Phase 3 |
| Recruiting | Radiotherapy Combined with Systemic Therapy Versus Systemic Therapy for Oligometastatic UTUCs NCT06652022 | Peking University First Hospital | N/A |
| Unknown | Circulating Biomarkers in Patients With Anal Cancer Treated With Induction Chemotherapy NCT05233540 | Aarhus University Hospital | — |
| Unknown | RESOLUTE Trial Aims to Investigate the Value of Adding Local Ablative Treatment to Standard Systemic Treatment NCT05862051 | Australasian Gastro-Intestinal Trials Group | N/A |
| Recruiting | Consolidative Radiotherapy Combined With Camrelizumab and Chemotherapy for Oligometastatic Nasopharyngeal Carc NCT05128201 | Jiangxi Provincial Cancer Hospital | Phase 2 |
| Unknown | Chemotherapy and Surgical Resection in Patients With Hepatic Oligometastatic Adenocarcinoma of the Pancreas NCT04617457 | University of Cologne | Phase 2 |
| Terminated | Comparison of Contrast Agents in Liver MR for the Detection of Hepatic Metastases NCT04973007 | University of Colorado, Denver | Phase 4 |
| Active Not Recruiting | Focal Radiation With Pulsed Systemic Therapy of Abiraterone, Androgen Deprivation Therapy (ADT), Lynparza Towa NCT04748042 | University of Michigan Rogel Cancer Center | Phase 2 |
| Completed | Efficacy and Safety of SBRT in Oligo-metastatic/Persistent/Recurrent Ovarian Cancer NCT04593381 | Gemelli Molise Hospital | N/A |
| Recruiting | MR-linac Guided Ultra-hypofractionated RT for Prostate Cancer (SMART-P01 and SMART-P02) NCT05183074 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | N/A |
| Completed | Study of PD-1 Antibody Combined With Chemoradiotherapy in Oligometastatic Esophageal Cancer NCT04821765 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Phase 2 |
| Recruiting | Standard Maintenance Therapy (SMT) vs Local Consolidative Radiation Therapy and SMT in OM-NSCLC NCT05278052 | Tata Memorial Hospital | Phase 3 |
| Unknown | Local Ablative Radiotherapy for OLIgoprogressive Castration Resistant Prostate Cancer NCT04141709 | Technische Universität Dresden | N/A |
| Recruiting | Local Consolidative Radiation Therapy Plus TKI Versus TKI Alone in Driver Mutated OM-NSCLC NCT05277844 | Tata Memorial Hospital | Phase 2 |
| Active Not Recruiting | Bony M - Stereotactic Ablative Radiotherapy (SABR) of Bony Metastases in Patients With Oligometastatic Disease NCT05101824 | Gitte Fredberg Persson MD PhD | N/A |
| Unknown | Stereotactic Ablative Radiotherapy in Synchronous and Metachronous Oligo-Metastatic Non Small Cell Lung Cancer NCT06207292 | Radiotherapy Oncology Centre "Santa Maria" Hospital | N/A |
| Completed | Percutaneous High-dose Radiotherapy in Patients With Oligometastases of Prostate Carcinoma NCT02264379 | Technische Universität Dresden | — |
| Terminated | Radiosurgery for Patients With Oligometastatic Disease at Initial Presentation NCT01345539 | Steven Burton | Phase 2 |