| Completed | The Effect of Obesity Hypoventilation Syndrome on Exercise Capacity, Peripheral Muscle Strength, and Quality o NCT06142513 | Istanbul University | — |
| Unknown | Evaluation of High Velocity Nasal Insufflation in Management of Respiratory Failure in Patients With Overlap S NCT05190458 | Assiut University | N/A |
| Suspended | Resting Energy Expenditure in Patients With OHS Treated With Long-term NIV NCT04474587 | University Hospital, Geneva | — |
| Unknown | Obesity-hypoventilation in Metabolic Syndrom Patients NCT04839419 | SOS Oxygene Mediterranee | — |
| Completed | Randomized Controlled Trial Between Auto-titration and Manual Titration of Non-invasive Ventilation in Obesity NCT04327336 | Sociedad Española de Neumología y Cirugía Torácica | N/A |
| Withdrawn | A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Obesity NCT04100616 | ProgenaBiome | — |
| Completed | Ketogenic Diet for Obesity Hypoventilation Syndrome NCT04108819 | Johns Hopkins University | N/A |
| Unknown | Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases NCT04098094 | Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil | — |
| Withdrawn | Medico-economics and QoL of Obese Patients Followed by Medical Analysis Laboratories (BIOSAOS ) NCT03861468 | University Hospital, Grenoble | N/A |
| Unknown | Respiratory Muscle Strength in Patients With Obesity Hypoventilation Syndrome (OHS) or With a Precursor of the NCT03854058 | Wissenschaftliches Institut Bethanien e.V | — |
| Terminated | Microbiologic Contamination of Home Non Invasive Ventilators NCT03809832 | University Hospital, Rouen | — |
| Completed | The Debated Role of Sleep Studies in Patients Under Established Home Mechanical Ventilation NCT03506906 | Wissenschaftliches Institut Bethanien e.V | N/A |
| Completed | Usefulness of Transcutaneous Capnography to Assess Residual Hypoventilation in Obesity-Hypoventilation Syndrom NCT03572712 | Nantes University Hospital | — |
| Unknown | Effects of PEEP on Heart and Lungs in Obese Subjects NCT02523352 | Massachusetts General Hospital | N/A |
| Terminated | Telemedicine for Improving Outcome in Inner City Patient Population With Hypercapneic Respiratory Failure NCT03353064 | Albert Einstein Healthcare Network | N/A |
| Unknown | Postoperative Complications in Patients With Obesity Hypoventilation Syndrome NCT02980770 | Marmara University | — |
| Completed | Effectiveness Monitoring of Home Non-invasive Mechanical Ventilation by Digital Diagnosis Platform NCT03085537 | Corporacion Parc Tauli | — |
| Terminated | Simplus and Eson Non-Invasive Ventilation (NIV) Evaluation - Germany NCT02726048 | Fisher and Paykel Healthcare | N/A |
| Completed | Myocardial Effects of NIV in OHS Patients NCT06486129 | Pavol Jozef Safarik University | N/A |
| Terminated | Toffee Full Face and Toffee Nasal Mask Evaluation in Obesity Hypoventilation Syndrome (NZ) NCT02486380 | Fisher and Paykel Healthcare | N/A |
| Terminated | Juno Perth Clinical Trial NCT02317042 | ResMed | N/A |
| Completed | Cost Effectiveness of Outpatient Set-up of Automated NIV in Obese Patients With Chronic Respiratory Failure NCT02342899 | Guy's and St Thomas' NHS Foundation Trust | Phase 3 |
| Terminated | Feasibility of a Modified Positive Airway Pressure Device to Treat Sleep Disordered Breathing NCT02368639 | Fisher and Paykel Healthcare | N/A |
| Completed | Prevalence Rate, and Clinical Characteristics of Obesity Hypoventilation Syndrome Via Screening Patients Admit NCT02934581 | National Taiwan University Hospital | — |
| Terminated | European Home Mechanical Ventilation Registry NCT02315339 | ResMed | — |
| Terminated | Predictive Factors of Obesity-hypoventilation Syndrome (OHS) Among Obese Subjects- ETUDE COHYPOB - NCT02021448 | University Hospital, Strasbourg, France | N/A |
| Terminated | Obesity Hypoventilation Syndrome Prevalence Study NCT01964339 | Philips Respironics | — |
| Completed | Prevalence of Obesity Hypoventilation Syndrome NCT01903135 | AGIR à Dom | N/A |
| Completed | Non Invasive Ventilation : Efficacy of a New Ventilatory Mode in Patients With OHS NCT01757444 | Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche | N/A |
| Completed | Target Volume in Noninvasive Positive Pressure Ventilation NCT01748656 | AGIR à Dom | N/A |
| Unknown | Telemedicine and Ventilator Titration in Chronic Respiratory Patients Initiating Non-invasive Ventilation NCT01560741 | Hospital Sao Joao | Phase 1 |
| Completed | Ventilator Monitoring in Early Exacerbation Detection NCT01644162 | ResMed | N/A |
| Completed | A Study to Investigate the Effects of Heated Humidification During Non-Invasive Ventilation NCT01372072 | Guy's and St Thomas' NHS Foundation Trust | N/A |
| Completed | A Trial of Rehabilitation in Obesity Hypoventilation Syndrome (OHS) NCT01483716 | Guy's and St Thomas' NHS Foundation Trust | N/A |
| Completed | Treatment of Metabolic Alkalosis With Acetazolamide. Effect on the Length of Mechanical Ventilation. NCT01499485 | Hospital Son Llatzer | Phase 3 |
| Completed | AVAPS-AE Efficacy Study NCT01368614 | Philips Respironics | N/A |
| Completed | Treatment for Obstructive Sleep Apnea Hypopnea Syndrome and Obesity Hypoventilation Syndrome (OHS) NCT01553227 | Nanjing Medical University | N/A |
| Completed | Factors Associated With Chronic Respiratory Failure in Obesity NCT01380418 | Oxford University Hospitals NHS Trust | — |
| Completed | Patient -Ventilator Interaction in Chronic Respiratory Failure NCT01371149 | Michelle Ramsay | Phase 2 |
| Withdrawn | Autotitrating Versus Standard Non-invasive Ventilation (NIV) in Acute Exacerbation of Respiratory Failure NCT01174316 | ResMed | N/A |
| Completed | PAP Therapy in Patients With Obesity Hypoventilation Syndrome NCT03449641 | University of Crete | N/A |
| Withdrawn | Target Volume Mode Controlled Ventilator in Obesity Hypoventilation Syndrome NCT01104610 | Breas Medical S.A.R.L. | N/A |
| Completed | Alternative of Treatment in Obesity Hypoventilation Syndrome NCT01405976 | Sociedad Española de Neumología y Cirugía Torácica | N/A |
| Completed | Efficacy of Average Volume Assured Pressure Support With Bi-Level Pressure Support Nocturnal Ventilation NCT00479284 | University Hospital, Geneva | N/A |
| Completed | The Obesity-hypoventilation Syndrome Study of Clinical Characteristics and Predictive Factors of Response to T NCT00938977 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | N/A |