NCT03449641

PAP Therapy in Patients With Obesity Hypoventilation Syndrome

PAP Therapy Compliance in Patients With Obesity Hypoventilation Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 252 (actual)
• Sponsor: University of Crete · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The role of different levels of compliance and long-term effects of positive airway pressure (PAP) therapy on gas exchange, sleepiness, quality of life, depression and death rate in patients with obesity hypoventilation syndrome (OHS).

Detailed description

Various forms of positive airway pressure (PAP) therapy are effective in providing short and long-term benefits in these patients with or without obstructive sleep apnea (OSA). However, there are limited data concerning the impact of long-term effects of PAP therapy on survival and functional status in individuals with obesity hypoventilation syndrome (OHS) and OSA. Therefore we aimed to assess the role of different levels of compliance and long-term effects of PAP on gas exchange, sleepiness, quality of life, depression and death rate in patients with OHS, two year after PAP initiation.

Conditions

• Obesity Hypoventilation Syndrome

Interventions

Type	Name	Description
DEVICE	Positive airway pressure (PAP)	Positive airway pressure (PAP) is a mode of respiratory ventilation used in the treatment of sleep apnea.

Timeline

• Start date: 2009-06-01
• Primary completion: 2012-06-01
• Completion: 2012-06-01
• First posted: 2018-02-28
• Last updated: 2018-03-01