NCT01748656

Target Volume in Noninvasive Positive Pressure Ventilation

Comparison of Two Noninvasive Positive Pressure Ventilation Devices Using Target Volume Modes in Obesity Hypoventilation Syndrome (OHS): A Pilot Randomized Crossover Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: AGIR à Dom · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Patients with OHS are efficiently managed with long term home-based nocturnal noninvasive positive pressure ventilation (NIPPV). Several NIPPV devices offer the feature of automatically adjusting pressure support (and/or respiratory back-up rate) on the basis of a pre-determined "ideal tidal volume" or "ideal ventilation". However algorithms used to achieve these ideal targets are different among different commercialized devices and the relative efficacy from an algorithm compared to another remains unknown. The main objective is this study is to compare two commercialized NIPPV that have this option

Detailed description

RESMED Stellar-150 (IVAPS mode)versus PHILIPS-RESPIRONICS A30 (AVAPS-mode).

Conditions

• Obesity Hypoventilation Syndrome

Interventions

Type	Name	Description
DEVICE	IVAPS	IVAPS mode (RESMED Stelar 150) during 1 night
DEVICE	AVAPS	AVAPS mode (PHILIPS-RESPIRONICS-A30) during 1 night

Timeline

• Start date: 2013-01-01
• Primary completion: 2013-09-01
• Completion: 2014-02-01
• First posted: 2012-12-12
• Last updated: 2014-03-14

Locations

1 site across 1 country: France