NCT03854058

Respiratory Muscle Strength in Patients With Obesity Hypoventilation Syndrome (OHS) or With a Precursor of the Disease

Multimodal Measurement of Respiratory Muscle Strength by Using Volitional and Non-volitional Tests in Patients With Obesity Hypoventilation Syndrome (OHS), Obesity-associated Hypoventilation and OHS-Risk-Patients to Evaluate Pathophysiological Determinants and Predictors for the Presence of a Sleep-related Hypoventilation Requiring Treatment in Obese Patients

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Wissenschaftliches Institut Bethanien e.V · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Using an extensive set of both volitional and non-volitional tests of respiratory muscle function and strength it is the aim of this study to * identify potential determinants for the development of obesity hypoventilation * to identify predictors for the presence of a sleep-related hypoventilation requiring treatment in obese patients

Conditions

• Obesity Hypoventilation Syndrome

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	magnetic phrenic nerve stimulation	cervical and cortical stimulation of N. Vagus

Timeline

• Start date: 2019-05-01
• Primary completion: 2024-12-01
• Completion: 2024-12-01
• First posted: 2019-02-26
• Last updated: 2023-12-15

Locations

1 site across 1 country: Germany