| Withdrawn | Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric and Neonatal AKI NCT05114057 | Children's Hospital Medical Center, Cincinnati | N/A |
| Not Yet Recruiting | Effect of N-acetylcysteine as Adjunct Therapy on the Clinical Outcome of Neonatal Sepsis NCT07380347 | Ain Shams University | Phase 3 |
| Completed | Effect of Vitamin D as Adjuvant Therapy in Preterm Infants With Neonatal Sepsis NCT07245277 | Universitas Padjadjaran | Phase 4 |
| Recruiting | Chlorhexidine Gluconate and Alcohol Hand Rubbing on Healthcare-associated Infection NCT07421323 | Alexandria University | N/A |
| Active Not Recruiting | A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant Women NCT06592586 | Minervax ApS | Phase 2 / Phase 3 |
| Not Yet Recruiting | Role of Presepsin as a Novel Biomarker in Diagnosis of Neonatal Sepsis NCT06633770 | Sohag University | — |
| Unknown | Using Machine Learning to Model Early-onset Neonatal Sepsis Risk in Uganda and Zimbabwe NCT06411405 | St George's, University of London | — |
| Not Yet Recruiting | Intravenous Methylene Blue for Treating Refractory Neonatal Septic Shock NCT06306001 | Post Graduate Institute of Medical Education and Research, Chandigarh | Phase 2 / Phase 3 |
| Unknown | Microbiology, Antimicrobial Resistance and Outcomes of Neonatal Sepsis in China NCT05089760 | Children's Hospital of Fudan University | — |
| Completed | Perinatal Conditions Influencing Morbidity, Mortality, and Medical Care in Newborns NCT06653374 | HOSPITAL GINECO OBSTETRICO ISIDRO AYORA | — |
| Unknown | Outcomes and Predictors of Mortality Among Preterm Infants With Neonatal Sepsis NCT06113653 | Assiut University | — |
| Unknown | Frequency and Severity of Thrombocytopenia in Neonatal Sepsis NCT05692128 | Assiut University | — |
| Completed | Late-onset Sepsis in Term and Pre-term Neonates and Infants up to 3 Months of Age NCT05856227 | Basilea Pharmaceutica | Phase 3 |
| Unknown | Role of Neutrophil CD64 and Monocyte HLA-DR Markers in the Dignosis of Neonatal Sepsis NCT05985174 | Sohag University | N/A |
| Unknown | Treatment Outcome With Antibiotic Use and Its Resistance Pattern Among Patient With Neonatal Sepsis NCT05742477 | Assiut University | — |
| Completed | Umbilical Cord Care in Term Neonates: The Role of Wondaleaf Adhesive Pouch (WLAP) NCT05569551 | AIMST University Malaysia | N/A |
| Unknown | THE VALUE OF INTERLEUKIN 6 AS A DIAGNOSTIC MARKER IN NEONATAL SEPSIS NCT05585957 | Sohag University | N/A |
| Unknown | Study of the Breast Milk Microbiota and Its Influence on the Development of Early and Late Neonatal Bacterial NCT05490498 | Assistance Publique Hopitaux De Marseille | N/A |
| Unknown | The Volume of Blood Submitted for Culture in Neonates - a Multicentre Quality Improvement Initiative. NCT04455022 | Medical University of Warsaw | — |
| Completed | Smart Discharges for Mom & Baby NCT05730387 | University of British Columbia | — |
| Completed | Clinical Value of Metagenomic Sequencing in Neonatal Sepsis NCT05416918 | Children's Hospital of Fudan University | — |
| Unknown | Parental Participation on the Neonatal Ward - the neoPARTNER Study NCT05343403 | Onze Lieve Vrouwe Gasthuis | — |
| Completed | Use of Probiotics to Reduce Infections, Death and ESBL Colonisation NCT04172012 | Haydom Lutheran Hospital | Phase 3 |
| Completed | Host RNA Expression Profiles and Protein Biomarkers in Neonatal Herpes Simplex Virus Infection NCT05226949 | Rigshospitalet, Denmark | — |
| Unknown | Potential Protective Effect of a Formula Supplemented With Fermented Matrices on the Risk of Developing Neonat NCT04742582 | Heinz Italia SpA | N/A |
| Suspended | Probiotics and GBS Colonization in Pregnancy NCT05156333 | University of Modena and Reggio Emilia | N/A |
| Completed | A Comparative Analysis of 4% Chlorhexidine Versus Methylated Spirit as Prophylaxis of Omphalitis and Sepsis in NCT06002295 | Sheikh Zayed Federal Postgraduate Medical Institute | Phase 2 |
| Completed | Azithromycin-Prevention in Labor Use Study (A-PLUS) NCT03871491 | NICHD Global Network for Women's and Children's Health | Phase 3 |
| Unknown | Comparison of the Effectiveness of Two Different Antibiotic Regimens of the Treatment of Pregnant Women With P NCT04528251 | Hacettepe University | — |
| Completed | Role of Montelukast in Modulation of Response to Sepsis in Preterm Infants NCT04474327 | Mansoura University Children Hospital | Phase 1 |
| Unknown | Salivary C- Reactive Protein, Mean Platelet Volume and Neutrophil Lymphocyte Ratio as Diagnostic Markers for N NCT04800445 | Cairo University | — |
| Unknown | Evaluating the NeoTree in Malawi and Zimbabwe NCT05127070 | University College, London | — |
| Unknown | White Blood Cells and Platelets Indices as a Prognostic Factor in Neonatal Sepsis NCT03880305 | Assiut University | — |
| Unknown | Neonatal Bacterial Colonization Study NCT03896893 | University of Stellenbosch | N/A |
| Completed | Serum Presepsin as Early Predictor for Neonatal Early-onset Sepsis NCT05022043 | Tanta University | N/A |
| Unknown | The Role of Neutrophil CD64 and Soluble Triggering Receptor Expressed on Myeloid Cells 1 in Neonatal Sepsis NCT03795285 | Assiut University | — |
| Unknown | Methylene Blue Versus Vasopressin Analogue for Treatment of Septic Shock in Preterm Neonate NCT04110418 | Ain Shams University | Phase 2 |
| Unknown | Prognostic Value of Red Cell Distribution Width (RDW) in Neonatal Sepsis NCT03403062 | Assiut University | — |
| Completed | Clinical Impact of an Antibiotic Stewardship Program in a Neonatal Intensive Care Unit NCT04039152 | Assiut University | — |
| Completed | 7 Days Versus 14 Days of Antibiotics for Neonatal Sepsis NCT03280147 | Indian Council of Medical Research | Phase 3 |
| Completed | Neonatal Sepsis at Neonatal Intensive Care Units in Ghana NCT03755635 | Stephanie Bjerrum | N/A |
| Completed | NeoAMR Observational Study in Neonatal Sepsis NCT03721302 | Drugs for Neglected Diseases | — |
| Unknown | A Panel of Biomarkers in Diagnosing Late-onset Neonatal Sepsis and Necrotizing Enterocolitis in Sibu Hospital NCT03578978 | Clinical Research Centre, Malaysia | — |
| Unknown | Effect of Early Feeding of Breast Milk NCT03498989 | Assiut University | N/A |
| Completed | Oral Probiotics to Reduce Vaginal Group B Streptococcal Colonization in Late Pregnancy NCT03008421 | Medical University of Vienna | N/A |
| Unknown | Bovine Lactoferrin and Neonatal Survival in Low Birth Weight Babies. NCT03431558 | Aga Khan University | Phase 3 |
| Completed | A Study on Ventilator-associated Pneumonia as a Risk for Nosocomial Infection in Mechanically Ventilated Neona NCT03310840 | Assiut University | — |
| Completed | Intravenous and Oral Fosfomycin in Hospitalised Neonates With Clinical Sepsis NCT03453177 | Drugs for Neglected Diseases | Phase 2 |
| Completed | Efficacy of IgM Rich Immunoglobulin With Antibiotics for Bacterial Sepsis in Very Low Birth Weight Preterm Neo NCT03403530 | Sir Takhtasinhji General Hospital | Phase 4 |
| Unknown | Epidemiology of Neonatal Sepsis in Neonatal Intensive Care Unit in Assiut University Children Hospital NCT03354650 | Assiut University | — |
| Completed | Safety and Efficacy of Oral Bovine Lactoferrin NCT04094597 | Cairo University | EARLY_Phase 1 |
| Active Not Recruiting | Microfluidic Assessment of Clinical Outcomes in Preterm Newborns NCT03291496 | University of Florida | — |
| Completed | Reduction of Intravenous Antibiotics In Neonates NCT03247920 | Franciscus Gasthuis | Phase 4 |
| Unknown | Prevailing Microorganisms Causing Neonatal Sepsis in Neonatal Intensive Care Unit (Prospective Study)Prevailin NCT03308526 | Gehad Abdelnaser | — |
| Completed | Pre-delivery Administration of Azithromycin to Prevent Neonatal Sepsis & Death NCT03199547 | London School of Hygiene and Tropical Medicine | Phase 3 |
| Completed | Severity Index of Neonatal Septicemia Using Score for Neonatal Acute Physiology (SNAP) II NCT03746743 | Ahmed Mahmoud Ali Ali Youssef | — |
| Completed | Outcomes in Spontaneous and ART Twin Pregnancies NCT03590483 | Hawler Medical University | — |
| Completed | Oropharyngeal Administration of Mother's Milk in Preterm Infants and Neonatal Infection NCT03513146 | Mansoura University Children Hospital | N/A |
| Completed | Effects of Melatonin as a Novel Antioxidant and Free Radicals Scavenger in Neonatal Sepsis NCT03295162 | Mohamed Hussein Metwally | Phase 1 / Phase 2 |
| Completed | Intravenous Immunoglobulin in Prevention of Preterm Neonatal Sepsis NCT02954926 | Hormozgan University of Medical Sciences | Phase 3 |
| Completed | Prevention of Nosocomial Bacteremia Among Zambian Neonates NCT02386592 | Boston University | N/A |
| Completed | Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana NCT02468310 | Hannah Brown Amoakoh | N/A |
| Completed | Infection, Sepsis and Meningitis in Surinamese Neonates NCT02486783 | Academic Hospital Paramaribo | — |
| Completed | Early Versus Late Lactoferrin in Prevention of Neonatal Sepsis NCT02959229 | Ain Shams University | Phase 4 |
| Unknown | Neonatal Sepsis Workup for High Risk Newborns - Evaluation of Need and Ways to Prevent NCT02061150 | Hillel Yaffe Medical Center | — |
| Completed | Effects of Cord Blood 25-hydroxy-vitamin D Level on Early Neonatal Morbidities NCT02147327 | Zekai Tahir Burak Women's Health Research and Education Hospital | — |
| Unknown | Oral Lactoferrin Supplementation for Prevention of Sepsis in Preterm Neonate NCT01821989 | Mooselmokadem | EARLY_Phase 1 |
| Completed | Strengthening Maternal Neonatal and Child Health Services in a Rural District of Pakistan NCT02797353 | Aga Khan University | N/A |
| Withdrawn | Chlorhexidine Skin Application for Prevention of Infection in Infants Weighing <1500 g at Birth NCT01723501 | All India Institute of Medical Sciences | Phase 2 / Phase 3 |
| Completed | Hepcidin Levels in Preterm Infants NCT01539356 | Meir Medical Center | — |
| Completed | Infant Pulse Oximetry in Pakistan Study NCT01676610 | The Hospital for Sick Children | — |
| Completed | A Study to Describe the Pharmacokinetics of Acyclovir in Premature Infants (PTN_Acyclo) NCT00942084 | Phillip Brian Smith | Phase 1 |
| Completed | Impact of Sunflower Seed Oil Massage on Neonatal Mortality and Morbidity in Nepal NCT01177111 | Johns Hopkins Bloomberg School of Public Health | Phase 3 |
| Completed | Role of Antibiotics in Preventing Infection in Babies Born Through Meconium Stained Liquor NCT01290003 | Lady Hardinge Medical College | N/A |
| Completed | Naushero Feroze Neonatal Survival Project NCT01350765 | Aga Khan University | N/A |
| Completed | Optimising Newborn Nutrition During Therapeutic Hypothermia. NCT03278847 | Imperial College London | — |
| Unknown | Soluble Urokinase Plasminogen Activator Receptor (suPAR) in Late-onset Neonatal Sepsis NCT01294865 | Ankara University | — |
| Completed | Simplified Antibiotic Therapy for Sepsis in Young Infants NCT01027429 | Aga Khan University | Phase 3 |
| Completed | CD64 Measurement in Neonatal Infection and Necrotising Enterocolitis NCT01005589 | Newcastle-upon-Tyne Hospitals NHS Trust | — |
| Completed | Effect of Recombinant Human Granulocyte Colony- Stimulating Factor on CD11b in Septic Neonates NCT01479114 | Ain Shams University | Phase 4 |
| Completed | Neonatal Sepsis and GBS Carriage Study NCT00861055 | University of Oxford | — |
| Completed | Improved Detection of Neonatal Sepsis Using a Targeted Biomarker Assay NCT01120678 | University of Virginia | — |
| Completed | Defects in Opsonophagocytosis in Premature Infants NCT00866567 | University Hospital, Geneva | — |
| Completed | Distribution of Haptoglobin Phenotype in Septic and Non Septic Pre-term Neonates (PTSH) NCT00800449 | Irina Kessel | — |
| Terminated | Probiotics for Prevention Neonatal Infection NCT01214473 | University of Nebraska | N/A |
| Completed | Safety of Skin Cleansing With Chlorhexidine in Preterm Low Birth Weight Infants NCT00947518 | All India Institute of Medical Sciences | N/A |
| Completed | Home Based Child Care to Reduce Mortality and Malnutrition in Tribal Children of Melghat, India: CRCT NCT02473796 | MAHAN Trust | N/A |
| Completed | Neurodevelopmental Outcomes After Suspected or Proven Sepsis: Secondary Analysis of INIS Trial Database NCT02281890 | University of Edinburgh | — |