Trials / Completed
CompletedNCT01479114
Effect of Recombinant Human Granulocyte Colony- Stimulating Factor on CD11b in Septic Neonates
In Vivo Effect of Recombinant Human Granulocyte Colony- Stimulating Factor on Neutrophilic Expression of CD11b in Septic Neonates
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 90 (actual)
- Sponsor
- Ain Shams University · Academic / Other
- Sex
- All
- Age
- 4 Weeks
- Healthy volunteers
- Accepted
Summary
The investigators aimed to evaluate the effect of G-CSF administration in septic neonates on neutrophil production and CD11b expression.
Detailed description
Neonates are susceptible to septicemia secondary to quantitative and qualitative neutrophilic defects. Granulocyte-colony stimulating factor (G-CSF) stimulates myeloid progenitor cell proliferation and induces selective neutrophil functions.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | rh-GCSF | 10 ug/kg/day intravenously for 3 days |
Timeline
- Start date
- 2009-04-01
- Primary completion
- 2010-05-01
- Completion
- 2010-05-01
- First posted
- 2011-11-24
- Last updated
- 2011-11-28
Source: ClinicalTrials.gov record NCT01479114. Inclusion in this directory is not an endorsement.