| Not Yet Recruiting | A Clinical Trial to Investigate Efficacy, Safety and Pharmacokinetics (PK) of Two LXE408 Oral Regimens and Ora Localized Cutaneous Leishmaniasis | Phase 2 | 2025-11-16 |
| Recruiting | Mycetoma Retrospective Data Collection Mycetoma | — | 2024-06-20 |
| Not Yet Recruiting | Stop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT) Human African Trypanosomiasis | Phase 3 | 2024-04-08 |
| Completed | LXE408 for Treatment of Visceral Leishmaniasis in Ethiopia, a Proof of Concept Study Primary Visceral Leishmaniasis | Phase 2 | 2024-03-29 |
| Completed | DDI Study of Single Oral Dose of Acoziborole With Sequential Co-administration of Midazolam and Dextromethorph Trypanosomiasis, African | Phase 1 | 2023-02-09 |
| Terminated | Eumycetoma Long-term Post-Treatment Follow-Up Study Eumycetoma | — | 2023-01-26 |
| Active Not Recruiting | A Phase II, Multicentre, Randomized, Two-arm Blinded Study to Assess the Efficacy and Safety of Two LXE408 Reg Primary Visceral Leishmaniasis | Phase 2 | 2022-12-27 |
| Completed | Pharmacokinetic, Efficacy, Safety and Tolerability Study of a Single Dose of Acoziborole in g-HAT Paediatric P Trypanosomiasis, African, Trypanosoma Brucei Gambiense; Infection, Sleeping Sickness | Phase 2 / Phase 3 | 2022-07-09 |
| Completed | Safety and Tolerability Study of Acoziborole in g-HAT Seropositive Subjects Trypanosomiasis, African, Trypanosoma Brucei Gambiense; Infection, Sleeping Sickness | Phase 2 / Phase 3 | 2021-12-30 |
| Active Not Recruiting | Emodepside Phase II Trial for Treatment of Onchocerciasis Onchocerciasis | Phase 2 | 2021-08-30 |
| Completed | Combination, Miltefosine Monotherapy for Cutaneous Leishmaniasis in New World Cutaneous Leishmaniases | Phase 3 | 2021-01-26 |
| Completed | ADME Study of Acoziborole in Healthy Subjects Trypanosomiases, African | Phase 1 | 2020-02-05 |
| Completed | Fexinidazole in Human African Trypanosomiasis Due to T. b. Rhodesiense Trypanosomiasis, African, Sleeping Sickness, Trypanosoma Brucei Rhodesiense; Infection | Phase 2 / Phase 3 | 2019-09-29 |
| Unknown | Lopinavir/r/ Lamivudine/ Abacavir as an Easy to Use Paediatric Formulation HIV | Phase 1 / Phase 2 | 2019-06-04 |
| Completed | Single Oral Dose Escalation Study of DNDI-0690 in Healthy Subjects Visceral Leishmaniasis, Cutaneous Leishmaniases | Phase 1 | 2019-04-04 |
| Completed | Study to Investigate Effect of Food and Safety of a New Formulation of Zoliflodacin Gonorrhea | Phase 1 | 2018-10-03 |
| Completed | NeoAMR Observational Study in Neonatal Sepsis Neonatal SEPSIS | — | 2018-08-16 |
| Completed | A Phase 1 Bioequivalence Study of a Test Tablet Formulation of Ravidasvir With the Reference Tablet Formulatio Bioequivalence Study | Phase 1 | 2018-06-05 |
| Unknown | Short Course Regimens for Treatment of PKDL (Sudan) PKDL - Post-Kala-Azar Dermal Leishmanioid | Phase 2 | 2018-05-09 |
| Completed | Intravenous and Oral Fosfomycin in Hospitalised Neonates With Clinical Sepsis Neonatal SEPSIS | Phase 2 | 2018-03-15 |
| Completed | Miltefosine/Paromomycin Phase III Trial for Treatment of Primary Visceral Leishmaniasis (VL) Patients in Easte Visceral Leishmaniasis | Phase 3 | 2018-01-24 |
| Completed | Safety, Tolerability and PK of Multiple-ascending Doses of Emodepside Filariasis | Phase 1 | 2017-11-14 |
| Completed | Oral Fexinidazole Dosing Regimens for the Treatment of Adults With Chronic Indeterminate Chagas Disease Chagas' Disease (Chronic) Nos | Phase 2 | 2017-11-13 |
| Completed | Relative Bioavailability Study of Emodepside IR-tablets and Solution Filariasis | Phase 1 | 2017-10-26 |
| Completed | Proof-of-Concept Superiority Trial of Fosravuconazole Versus Itraconazole for Eumycetoma in Sudan Mycetoma | Phase 2 | 2017-05-09 |
| Completed | Thermotherapy + a Short Course of Miltefosine for the Treatment of Uncomplicated Cutaneous Leishmaniasis in th Cutaneous Leishmaniasis | Phase 2 | 2016-12-01 |
| Unknown | BENDITA BEnznidazole New Doses Improved Treatment and Associations Chagas Disease | Phase 2 | 2016-11-30 |
| Completed | Fexinidazole in Human African Trypanosomiasis Due to T.b. Gambiense at Any Stage Trypanosomiasis, African, Sleeping Sickness, Trypanosomiasis; Gambian | Phase 3 | 2016-11-10 |
| Completed | Efficacy and Safety of Acoziborole (SCYX-7158) in Patients With Human African Trypanosomiasis Due to T.b. Gamb Trypanosomiasis, African, Gambiense Trypanosomiasis, Sleeping Sickness | Phase 2 / Phase 3 | 2016-10-11 |
| Unknown | Strategic Transformation of the Market of HCV Treatments Hepatitis C | Phase 2 / Phase 3 | 2016-09-01 |
| Completed | First in Man Clinical Trial of Emodepside (BAY 44-4400) Healthy Volunteers | Phase 1 | 2015-12-01 |
| Completed | Prospective Study of Lopinavir Based ART for HIV Infected childreN Globally (LIVING Study) HIV | Phase 3 | 2015-09-01 |
| Completed | Pharmacokinetics/Safety of Miltefosine Allometric Dose for the Treatment of Visceral Leishmaniasis in Children Visceral Leishmaniasis | Phase 2 | 2015-05-01 |
| Completed | Bioequivalence Study - Reference Clinical Fexinidazole Tablet Versus Proposed Market Formulation Trypanosomiasis, African | Phase 1 | 2015-03-01 |
| Completed | Pharmacokinetic Drug-Drug Interaction Study Chagas Disease | Phase 1 | 2014-10-01 |
| Completed | Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of Visceral Leishmaniasis | Phase 3 | 2014-07-01 |
| Unknown | Study to Evaluate Fexinidazole Dosing Regimens for the Treatment of Adult Patients With Chagas Disease Chagas Disease, Trypanosomiasis, South American, South American Trypanosomiasis | Phase 2 | 2014-07-01 |
| Completed | Efficacy and Safety of Fexinidazole in Children at Least 6 Years Old and Weighing Over 20 kg With Human Africa Human African Trypanosomiasis (HAT) | Phase 2 / Phase 3 | 2014-05-03 |
| Completed | Efficacy and Safety of Fexinidazole in Patients With Stage 1 or Early Stage 2 Human African Trypanosomiasis (H Human African Trypanosomiasis (HAT) | Phase 2 / Phase 3 | 2014-04-30 |
| Completed | Topical 3% Amphotericin B Cream for the Treatment of Cutaneous Leishmaniasis in Colombia Cutaneous Leishmaniasis | Phase 1 / Phase 2 | 2014-02-01 |
| Terminated | Trial to Determine Efficacy of Fexinidazole in Visceral Leihmaniasis Patients in Sudan Visceral Leishmaniasis | Phase 2 | 2013-11-01 |
| Completed | Pharmacokinetics of Lopinavir/Ritonavir Superboosting in Infants and Young Children Co-infected With HIV and T Acquired Immunodeficiency Syndrome, Tuberculosis | Phase 4 | 2013-01-01 |
| Completed | Pivotal Study of Fexinidazole for Human African Trypanosomiasis in Stage 2 Human African Trypanosomiasis (HAT), Sleeping Sickness | Phase 2 / Phase 3 | 2012-10-01 |
| Completed | Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the SCYX-7158 Trypanosomiasis, Trypanosomiasis, African, Protozoan Infections | Phase 1 | 2012-02-01 |
| Terminated | Multiple Dose Study to Evaluate Security, Tolerance and Pharmacokinetic of Fexinidazole (Drug Candidate for Hu Trypanosomiasis, African | Phase 1 | 2011-09-01 |
| Unknown | Proof-of-Concept Study of E1224 to Treat Adult Patients With Chagas Disease Chronic Chagas Disease, Indeterminate | Phase 2 | 2011-06-01 |
| Completed | Population Pharmacokinetics Study of Benznidazole in Children With Chagas'Disease Chagas' Disease | Phase 4 | 2011-05-01 |
| Completed | Optimization of PCR Technique to Assess Parasitological Response for Patients With Chronic Chagas Disease Chagas Disease | Phase 4 | 2011-04-01 |
| Completed | Fexinidazole (1200mg) Bioavailability Under Different Food Intake Conditions PK in Healthy Volunteers | Phase 1 | 2011-02-01 |
| Completed | Phase III, Study of Three Short Course Combo (Ambisome®, Miltefosine, Paromomycin) Compared With AmBisome for Visceral Leishmaniasis | Phase 3 | 2010-05-01 |
| Completed | Clinical Trial to Assess the Safety and Efficacy of Sodium Stibogluconate (SSG) and AmBisome® Combination, Mil Primary Visceral Leishmaniasis | Phase 2 | 2010-03-01 |
| Completed | Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the Fexinidazole Human African Trypanosomiasis | Phase 1 | 2009-09-01 |
| Terminated | Open-Label, Sequential Step, Safety and Efficacy Study to Determine the Optimal Single Dose of Ambisome for Pa Visceral Leishmaniasis | Phase 2 | 2009-04-01 |
| Completed | Clinical Study to Assess the Tolerability, Feasibility and Effectiveness of Nifurtimox and Eflornithine (NECT) Human African Trypanosomiasis | Phase 4 | 2009-04-01 |
| Completed | Safety and Efficacy Study to Evaluate Different Combination Treatment Regimens for Visceral Leishmaniasis Visceral Leishmaniasis | Phase 3 | 2008-06-01 |
| Completed | Imiquimod Plus Antimony Immunochemotherapy for Cutaneous Leishmaniasis Cutaneous Leishmaniasis | Phase 3 | 2005-12-01 |
| Completed | Efficacy/Safety of Sodium Stibogluconate (SSG) Versus Paromomycin (PM) and SSG/PM Combination to Treat V Leish Visceral Leishmaniasis | Phase 3 | 2004-11-01 |
| Completed | Efficacy - Safety of Eflornithine-Nifurtimox Combination Versus Eflornithine to Treat Human African Trypanosom Trypanosomiasis, African | Phase 3 | — |