Trials / Conditions / Mitral Valve Insufficiency

Mitral Valve Insufficiency

96 registered clinical trials studyying Mitral Valve Insufficiency — 13 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Korea VHD Echo Study: Surveillance of Aortic, Mitral & Tricuspid Patients - Insights From Real-world Practice NCT07068633	Yonsei University	—
Not Yet Recruiting	A Study of Mitral Annular Disjunction in Mitral Valve Prolapse Patients and Arrhythmia Risk NCT06741709	Assiut University	—
Recruiting	Clinical Outcomes of Edwards Lifesciences MITRIS RESLILA Mitral Valve in the Asian Population NCT06757049	Asan Medical Center	—
Recruiting	European Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study NCT06235385	Assistance Publique - Hôpitaux de Paris	—
Recruiting	DragonFly EU Pivotal Study NCT05927441	Hangzhou Valgen Medtech Co., Ltd	N/A
Completed	Study on Surgical Treatment Strategies for Moderate Ischemic Mitral Regurgitation NCT06408779	China National Center for Cardiovascular Diseases	—
Unknown	Clinical Investigation for the Foldax Tria Mitral Valve- India NCT06191718	Foldax, Inc	N/A
Unknown	Evaluation of Mitral Valve Insufficiency Under General Anesthesia NCT05736289	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	—
Active Not Recruiting	Real-world Clinical Outcomes of the MITRIS RESILIA Mitral Valve NCT05526560	Edwards Lifesciences	—
Completed	Aortic or Mitral Valve Replacement With the Braile Biomédica® Bovine Pericardium Valvular Bioprosthesis NCT05902897	Braile Biomedica Ind. Com. e Repr. Ltda.	—
Not Yet Recruiting	To Evaluate the Efficacy and Safety of the Transfemoral Mitral Valve Repair System in the Treatment of Patient NCT05508438	Pan Xiangbin	N/A
Unknown	European FIH Study - NeoChord Transcatheter Mitral Repair System for Symptomatic Mitral Regurgitation NCT05425628	NeoChord	N/A
Completed	Effect of Anesthetics on Troponin I and С-reactive Protein NCT05742789	Astana Medical University	Phase 1
Recruiting	REvascularization and Valve Intervention for Ischemic Valve diseasE: REVIVE Trial NCT04822675	Ottawa Heart Institute Research Corporation	N/A
Unknown	Mi-STITCH™ and Mi-KNOT™ Device Technologies - Improvement of Mitral Valve Repair NCT05034471	Medical University of Vienna	N/A
Withdrawn	Acquisition of Objective Data During Transapical Neochordae Implantation NCT04709042	Hospices Civils de Lyon	N/A
Unknown	Erector Spinae Plane Block for Minimally Invasive Mitral Valve Surgery NCT04770961	University of California, San Francisco	N/A
Completed	The Effects of Sevoflurane, Isoflurane and Propofol During Cardiac Surgery NCT05695287	Astana Medical University	Phase 1
Recruiting	The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study NCT04343313	Half Moon Medical	N/A
Recruiting	The ENCIRCLE Trial NCT04153292	Edwards Lifesciences	N/A
Completed	Ertugliflozin for Functional Mitral Regurgitation NCT04231331	Asan Medical Center	Phase 3
Completed	Transcatheter Mitral Valvuloplasty Pilot Study NCT04351984	Duk-Woo Park, MD	—
Unknown	The Effect of Posterior Annulus Elevation Technique in Reducing Residual Regurgitation During Mitral Valve Rep NCT04518709	National Cardiovascular Center Harapan Kita Hospital Indonesia	N/A
Unknown	TransCranial Doppler for REDUCtion of Silent strokE During MitraClip Implantation NCT04384198	Charite University, Berlin, Germany	N/A
Recruiting	Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System NCT04190602	NeoChord	—
Terminated	Impact of Mitral Regurgitation on Coronary Haemodynamics and Instantaneous Effect of Transcatheter Mitral Valv NCT04245956	University Hospital, Geneva	N/A
Completed	Influence of Anesthetics on Clinical Outcome in Mitral and Aortic Valve Replacement in Adults NCT05696509	Astana Medical University	Phase 3
Terminated	Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Mitral Regurgitation NCT04098328	Polares Medical SA	—
Recruiting	Prognostic Impact of Imaging Parameters in Patients With Primary Mitral Insufficiency by Prolapse (COHORTE-IM) NCT03962023	Lille Catholic University	—
Completed	Edwards PASCAL Transcatheter Valve Repair System Registry NCT04443218	Edwards Lifesciences	—
Unknown	The Conveyor Study NCT03893578	Synecor, LLC	N/A
Completed	Percutaneous Mitral Valve Intervention: Predicting Improvements in Left Ventricular Performance NCT04156295	Guy's and St Thomas' NHS Foundation Trust	—
Active Not Recruiting	Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System NCT03433274	Abbott Medical Devices	N/A
Completed	Operative Mitral Valve Reconstruction in Functional mv Insufficiency With Reduced Systolic Ventricle Function NCT03470155	Institut für Pharmakologie und Präventive Medizin	—
Unknown	Primary Mitral Regurgitation Repair NCT04067635	Eric Y. Yang, MD PhD	—
Recruiting	Personalized Activity Intervention in Rehabilitation After Cardiac Operations (the PACO Trial) NCT03470246	Kuopio University Hospital	N/A
Terminated	MitrAl ValvE RepaIr Clinical Trial (MAVERIC Trial) - United States NCT03311295	Mvrx, Inc.	N/A
Unknown	ChordArt System for Mitral Regurgitation NCT03581656	CoreMedic GmbH	N/A
Active Not Recruiting	PARTNER 3 Trial - Mitral Valve in Valve NCT03193801	Edwards Lifesciences	N/A
Recruiting	The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR NCT03142152	Cardiac Dimensions, Inc.	N/A
Completed	HighLife™ Transcatheter Mitral Valve Replacement System Study NCT02974881	HighLife SAS	N/A
Unknown	Clinical and Geriatric Assessment in Elderly Patients Before and After TAVI or MitraClip Positioning NCT03145376	University of Roma La Sapienza	—
Terminated	Safety and Performance Study of the Harpoon Mitral Valve Repair System NCT03285724	Edwards Lifesciences	N/A
Completed	Annular Reshaping of the Mitral Valve for Patients With Mitral Regurgitation Using the Millipede IRIS System NCT02607527	Boston Scientific Corporation	N/A
Active Not Recruiting	Long Term Follow Up for CTSN Mitral Valve Repair Studies NCT03066050	Icahn School of Medicine at Mount Sinai	—
Unknown	Mitral Valve Repair Combined Coronary Artery Bypass Grafting(CABG) Verus CABG Alone on Functional Ischemic Mit NCT03525041	Beijing Anzhen Hospital	N/A
Unknown	MRI as a Predictor of Outcomes in Patients Undergoing Mitral Valve Surgery NCT03012178	Atlantic Health System	—
Withdrawn	The RESHAPE-HF1-FU Study NCT02444286	Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH	—
Active Not Recruiting	Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair NCT02803957	NeoChord	N/A
Withdrawn	Safety and Performance of the AccuCinch® System NCT02624960	Ancora Heart, Inc.	N/A
Completed	The CorCinch - Functional Mitral Valve Regurgitation (FMR) Study NCT02806570	Ancora Heart, Inc.	N/A
Terminated	REPAIR - transcatheteR rEPair of mitrAl Insufficiency With caRdioband System NCT02703311	Edwards Lifesciences	N/A
Completed	CE Mark Study for the Harpoon Medical Device NCT02768870	Edwards Lifesciences	N/A
Completed	Degenerative Mitral Regurgitation in Intermediate Risk Patients NCT02604745	Northwestern University	—
Completed	Pharmacological Reduction of Functional, Ischemic Mitral REgurgitation NCT02687932	Asan Medical Center	Phase 4
Unknown	MitraClip® and Hemodynamic Effects of Relevant Iatrogenic Atrial Septum Defect Closure NCT03024268	Heart Center Leipzig - University Hospital	N/A
Completed	CE Mark Study for the Harpoon Medical Device in Poland NCT02432196	Edwards Lifesciences	N/A
Completed	Carillon Mitral Contour System® for Reducing Functional Mitral Regurgitation NCT02325830	Cardiac Dimensions Pty Ltd	N/A
Terminated	High and Intermediate Risk Degenerative Mitral Regurgitation Treatment: A Trial Comparing MitraClip® to Surgic NCT02534155	University of Zurich	Phase 4
Active Not Recruiting	Transcatheter Mitral Valve Replacement System (TMVR) Pilot Study and The Early Feasibility Study of the TMVR T NCT02322840	Medtronic Cardiovascular	N/A
Completed	A Clinical Evaluation of the Safety and Effectiveness of the MitraClip System in the Treatment of Clinically S NCT02444338	University Medical Center Goettingen	N/A
Completed	Physical and Functional Recovery From Cardiac Surgery in Hospitalized Patients: A Feasibility Pilot Study NCT02375282	Baystate Medical Center	N/A
Completed	Safety and Early Feasibility Study of the Harpoon Medical Device (EFS) NCT02771275	Edwards Lifesciences	N/A
Unknown	A Multicenter, Randomized, Controlled Study to Assess Mitral vAlve reconsTrucTion for advancEd Insufficiency o NCT02371512	Universitätsklinikum Köln	N/A
Completed	Belgian Mitraclip Registry NCT02506387	Universiteit Antwerpen	—
Completed	Normal Values in Stress Echocardiographic Parameters in Patients After Successful Mitral Valve Repair for Orga NCT02371863	UMC Utrecht	—
Terminated	Twelve Transcatheter Mitral Valve Replacement (TMVR) Pilot Study NCT02428010	Medtronic Cardiovascular	N/A
Unknown	Magnetic Resonance Imaging for Cerebral Embolization During Minimal Invasive Mitral Valve Surgery NCT02818166	University of Turin, Italy	N/A
Completed	Examination of Valve Insufficiency Before and After MitraClip or TAVI Procedure by 3D Echocardiography Compare NCT01966146	RWTH Aachen University	N/A
Completed	NeoChord TACT Post-Market Surveillance Registry NCT01784055	NeoChord	—
Terminated	The Dutch Asymptomatic Mitral Regurgitation Trial NCT01708265	UMC Utrecht	N/A
Completed	EASE MITRAL Expertise-based Assessment Study on Clinical Efficacy of Profile 3D in MITRAL Valve Annuloplasty NCT01112566	Medtronic Cardiac Rhythm and Heart Failure	—
Completed	The Use of Paravertebral Block for Cardiac Surgery NCT02180893	NYU Langone Health	Phase 4
Active Not Recruiting	ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New T NCT01757665	Edwards Lifesciences	N/A
Unknown	Surgical Treatment of Ischemic Mitral Regurgitation NCT01368575	Meshalkin Research Institute of Pathology of Circulation	Phase 4
Completed	Left Atrial Distensibility to Predict Left Ventricular Filling Pressure and Prognosis in Patients With Severe NCT01172184	Kaohsiung Veterans General Hospital.	—
Completed	Biomarkers in Aortic Stenosis - B.A.S.S. NCT01334801	Mayo Clinic	—
Completed	CARDINAL Adjustable Annuloplasty Ring System For Treatment of Mitral Regurgitation NCT01137734	Edwards Lifesciences	N/A
Completed	Surgical Ablation Versus No Surgical Ablation for Patients With Atrial Fibrillation Undergoing Mitral Valve Su NCT00903370	Annetine Gelijns	Phase 2
Unknown	Study of Administration Of Antithrombin in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Su NCT01201070	University of Bari	Phase 4
Completed	CG Future® Annuloplasty Ring/Band Clinical Trial NCT01074671	Medtronic Cardiac Rhythm and Heart Failure	Phase 4
Completed	Real World Expanded Multicenter Study of the MitraClip® System (REALISM) NCT01931956	Abbott Medical Devices	N/A
Completed	Comparing the Effectiveness of a Mitral Valve Repair Procedure in Combination With Coronary Artery Bypass Graf NCT00806988	Icahn School of Medicine at Mount Sinai	N/A
Unknown	Determinants of the Progression and Outcome of Mitral Regurgitation NCT01835054	Laval University	—
Completed	Comparing the Effectiveness of Repairing Versus Replacing the Heart's Mitral Valve in People With Severe Chron NCT00807040	Icahn School of Medicine at Mount Sinai	Phase 2
Completed	Multicenter International Trial Ring AnnulopLasty NCT00727012	Abbott Medical Devices	N/A
Terminated	Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regu NCT00608140	Duke University	Phase 3
Withdrawn	Prospective Study Looking at Quality of Life Measures in Non-ischaemic Cardiomyopathy After Mitral Valve Repai NCT00483236	McGill University Health Centre/Research Institute of the McGill University Health Centre	—
Terminated	Using Beta Blockers to Treat Mitral Regurgitation NCT00700947	Wake Forest University Health Sciences	Phase 1
Completed	Aortic or Mitral Valve Replacement With the Biocor and Biocor Supra NCT00636987	Abbott Medical Devices	N/A
Unknown	Should we Repair Ischemic Mitral Regurgitation? NCT00443365	Medical University of Silesia	N/A
Completed	EVEREST II Pivotal Study High Risk Registry (HRR) NCT01940120	Abbott Medical Devices	N/A
Completed	Pivotal Study of a Percutaneous Mitral Valve Repair System NCT00209274	Abbott Medical Devices	N/A
Completed	Safety and Efficacy of TP10, a Complement Inhibitor, in Adult Women Undergoing Cardiopulmonary Bypass Surgery NCT00082121	Avant Immunotherapeutics	Phase 2
Completed	Feasibility Study of a Percutaneous Mitral Valve Repair System. NCT00209339	Abbott Medical Devices	Phase 1 / Phase 2
Completed	Investigation of Heart Function in Patients With Heart Valve Defects NCT00001314	National Heart, Lung, and Blood Institute (NHLBI)	—