Trials / Unknown
UnknownNCT01201070
Study of Administration Of Antithrombin in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery
Effects of the Administration Of Antithrombin on the Coagulation Status and on the Inflammatory Response in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 90 (estimated)
- Sponsor
- University of Bari · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
General and specific objectives of the search: evaluate the effects of the administration of Antithrombin III (ATIII) on the activation of the coagulation system and of the fibrinolysis, platelet function, inflammatory response and markers of organ damage in patients undergoing cardiac surgery by cardiopulmonary bypass (CPB) with low plasma levels of post-operative Antithrombin (AT).
Conditions
- Aortic Valve Insufficiency
- Aortic Valve Stenosis
- Mitral Valve Insufficiency
- Mitral Valve Stenosis
- Acute Coronary Syndrome
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | antithrombin III | 3000 IU bolus at the time of randomization vs the study group 1000 IU after 8 h (24 h G0) 1000 IU after 16 h (8 h G1) TOTAL 5000/UI 24h |
Timeline
- Start date
- 2009-09-01
- Primary completion
- 2011-11-01
- Completion
- 2011-11-01
- First posted
- 2010-09-14
- Last updated
- 2010-09-15
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT01201070. Inclusion in this directory is not an endorsement.