| Not Yet Recruiting | EMBRACE Study: Enduring Migraine Benefit From Responsive Artery Coil Embolization NCT07313800 | Cortex Neurovascular | N/A |
| Not Yet Recruiting | Amylin-Induced Migraine Attacks Without Aura NCT07340788 | Danish Headache Center | N/A |
| Recruiting | Effects of PFO Closure on Glymphatic Function and Clinical Symptoms in Patients With Migraine NCT07170176 | First Affiliated Hospital Xi'an Jiaotong University | N/A |
| Recruiting | Evaluation of Efficacy and Safety of Topical Cannabidiol (Canvert-M Produced by Alasht Pharmed co. Iran) in th NCT07093138 | Alasht Pharmed | Phase 4 |
| Recruiting | The Role of Cytokines and Regulatory T Lymphocytes in Migraine Pathophysiology. NCT06426316 | University Hospital, Clermont-Ferrand | N/A |
| Withdrawn | Healthy Living Partnerships for Veterans With Migraine NCT04373330 | Wake Forest University Health Sciences | N/A |
| Recruiting | Treatment of Episodic Migraine With AURICular Neuromodulation NCT06623188 | Hôpital Européen Marseille | N/A |
| Not Yet Recruiting | Exploring Clinical Trial Experiences of Patients With Migraine NCT05675189 | Power Life Sciences Inc. | — |
| Recruiting | Closed-loop RTMS for Short-term Migraine Prevention NCT06735768 | Brightmind.AI | N/A |
| Recruiting | Trigeminal Brainstem Mapping 2: Higher Cortical Strucureas As Well As Subnuclei of the Spinal Trigeminal Nucle NCT06535880 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Not Yet Recruiting | Role of Ultrasound Guide Greater Occipital Nerve Block at Second Cervical Vertebra in Migraine Headache Prophy NCT06432127 | Mahidol University | Phase 4 |
| Completed | Educational Video Program to Promote Physical Activity and Reduce Migraine Frequency in Adults With Migraine NCT06993545 | Universidade do Porto | N/A |
| Enrolling By Invitation | Migraine Medication Effects on Urinary Symptoms NCT06212661 | The Cleveland Clinic | — |
| Unknown | Lacosamide Versus Topiramate in Migraine NCT06243692 | Kafrelsheikh University | Phase 3 |
| Recruiting | Migraine Attack Treatment Response Molecular and Clinical BiOmarkers (MAMBO) Phase I NCT06503848 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Completed | Reliability of Rimegepant or Triptans for the Acute Treatment of Migraine NCT06412965 | Pfizer | — |
| Unknown | Real-world Effectiveness and Tolerability of Triptans-Ditans-Gepants (TRIDIGEP) NCT06267664 | Hospital Clínico Universitario de Valladolid | — |
| Unknown | Education on Migraine in Pregnant Women NCT06054399 | Clinica Alemana de Santiago | N/A |
| Unknown | An Open Label, Study of DaxibotulinumtoxinA for Migraine Prevention NCT06154070 | Ki Health Partners. LLC | — |
| Completed | Videonystagmography and Vestibular Migraine NCT07000929 | Dr. med. Lukas Becker | — |
| Recruiting | Migraine Attack Pain Phase Prediction Study NCT06459635 | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | — |
| Completed | "Potential Effects of Virtual Reality Technology on the Treatment of Migraine-Type Headaches" NCT06061588 | Ankara City Hospital Bilkent | N/A |
| Recruiting | Tai Chi for the Prophylaxis of Episodic Migraine: the Efficacy Examination and Mechanism Exploration NCT05690737 | The Hong Kong Polytechnic University | N/A |
| Recruiting | Responding With Evidence and Access for Childhood Headaches NCT05889624 | Children's Hospital Medical Center, Cincinnati | N/A |
| Unknown | Predict the Response to Acute Treatment of Migraine With Rimegepant 75 mg NCT05888766 | University of Roma La Sapienza | — |
| Recruiting | Searching for Novel Biological Phenotypes in Migraine Patients Resistant to Treatments NCT06562413 | IRCCS National Neurological Institute "C. Mondino" Foundation | — |
| Recruiting | Biochemical Profiling of Migraine Patients NCT06549270 | IRCCS National Neurological Institute "C. Mondino" Foundation | — |
| Recruiting | Searching for Novel Therapeutic Approaches in Migraine Patients Resistant to Treatments NCT06562400 | IRCCS National Neurological Institute "C. Mondino" Foundation | — |
| Completed | Effects of Active Release Technique and Instrument Assisted Soft Tissue Mobilization in Patients With Migraine NCT06197542 | Riphah International University | N/A |
| Unknown | The Association Among Headache Severity, Head Posture, Cervical Muscle Endurance, and Neck Disorders in Indivi NCT05797012 | Tokat Gaziosmanpasa University | N/A |
| Unknown | Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic P NCT05780450 | Fundación Universidad Católica de Valencia San Vicente Mártir | N/A |
| Completed | Emotional Awareness and Expression Therapy (EAET) as a Novel Migraine Treatment NCT05837650 | University of Utah | N/A |
| Completed | Effects of tDCS and Physical Therapy in Chronic Migraine NCT05706077 | Federal University of Paraíba | N/A |
| Terminated | Emotional Awareness and Expression Therapy (EAET) for Migraine NCT05755698 | University of Utah | N/A |
| Unknown | The FreMRI Study: Advanced MRI on Migraine Patients Treated With Fremanezumab NCT06244823 | Hospital Clínico Universitario de Valladolid | Phase 4 |
| Recruiting | Valproate Versus Propranolol in Migraine NCT06485726 | Kafrelsheikh University | Phase 4 |
| Recruiting | EptinezuMaB in ReAl-world evidenCE: Multicenter, Real Life, Cohort Study in Migraine. NCT05570149 | IRCCS San Raffaele Roma | — |
| Unknown | Progressive Relaxation Training Effect On Pain, Activity And Social Participation In Women With Tension-Type H NCT06050382 | Hacettepe University | N/A |
| Unknown | Habituation of the Nociceptive Blink Reflex in Experimentally Induced Migraine Attack NCT05718310 | IRCCS National Neurological Institute "C. Mondino" Foundation | N/A |
| Completed | Migraine Difficult to Treat: the Importance of Psychological Care in the Chronic Patient NCT05658185 | University of Valencia | N/A |
| Unknown | Longitudinal Study of the Patients With Medication-overuse Headache or Migraine That Completed Baseline MRI NCT05528081 | Wei Dai | — |
| Unknown | Proximal and Distal Approach GON RFT in Migraine NCT05888298 | Diskapi Teaching and Research Hospital | N/A |
| Recruiting | Determining the Utility of a Behavioral Intervention in Chronic Migraine NCT05415020 | Mayo Clinic | N/A |
| Completed | The Lacosamide's Effect on Calcitonin Gene-related Peptide in Migraine Patients NCT05632133 | Kafrelsheikh University | Phase 3 |
| Completed | Lacosamide Versus Propranolol in Migraine NCT05851781 | Kafrelsheikh University | Phase 3 |
| Completed | Valproate Versus Topiramate in Migraine NCT06248931 | Kafrelsheikh University | Phase 3 |
| Recruiting | Specified Drug Use Survey on AJOVY Subcutaneous Injection for Long-term Use NCT05342493 | Otsuka Pharmaceutical Co., Ltd. | — |
| Active Not Recruiting | Potential Osteocatabolic Effect Caused by Anti-CGRP mAbs in Migraine Patients Treated With Anti-CGRP mAbs - an NCT06035458 | Ente Ospedaliero Cantonale, Bellinzona | — |
| Completed | A Pilot Clinical Trial of a New Neuromodulation Device for Acute Attacks of Migraine in Children and Adolescen NCT05102591 | University of Calgary | Phase 3 |
| Completed | Dietary Advanced Glycation End Products and Migraine NCT05747911 | Karabuk University | — |
| Active Not Recruiting | Digital CBTI for Comorbid Insomnia in Chronic Migraine NCT05244889 | University of Strathclyde | N/A |
| Recruiting | Idebenone for the Preventive Treatment of Migraine NCT04151472 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 3 |
| Completed | An Open Internet-based Survey and Natural Language Processing Project Analysing Written Monologues by Headache NCT05153876 | University Hospital, Ghent | — |
| Active Not Recruiting | Intervention for Sleep and Pain in Youth: a Randomized Controlled Trial NCT04936321 | Seattle Children's Hospital | N/A |
| Terminated | Fremanezumab, Migraine and Sleep NCT04693533 | Beth Israel Deaconess Medical Center | Phase 4 |
| Unknown | Transcutaneous Pulsed Radiofrequency in Migraine NCT05499689 | Diskapi Teaching and Research Hospital | N/A |
| Active Not Recruiting | Migraine Manager (R01) NCT04567355 | Children's Hospital Medical Center, Cincinnati | Phase 2 |
| Recruiting | (Italian Migraine Registry, I-GRAINE-NEW) NCT07163416 | IRCCS San Raffaele Roma | — |
| Unknown | Pain Resilience and Holistic Health Care of Migraine NCT04743492 | Changhua Christian Hospital | N/A |
| Completed | The Impact of nCoV-2019 on Children With Migraine NCT06077006 | Bnai Zion Medical Center | — |
| Unknown | My Healthy Diary - An Electronic Diary for Remote Migraine Monitoring NCT04828941 | Unidade Local de Saúde de Matosinhos, EPE | N/A |
| Recruiting | Mind Body Balance for Pediatric Migraine NCT04715685 | Children's Hospital Medical Center, Cincinnati | N/A |
| Recruiting | Qudexy XR for the Prevention of Migraine in Children 6 to 11 Years Old NCT04748601 | Upsher-Smith Laboratories | Phase 4 |
| Completed | Comparison of Craniosacral Therapy and Myofacial Relaxation Techniques in People Diagnosed With Migraine NCT04976725 | Alanya Alaaddin Keykubat University | N/A |
| Completed | Temporal, Environmental, and Genetic Factors Regulating Exercise and Migraine NCT04553445 | University of Nevada, Las Vegas | N/A |
| Completed | Management of Migraine Using Enerumab and Traditional Therapy at the Time of COVID-19 NCT05052008 | Fayoum University | — |
| Completed | Comparison of Great Occipital Nerve and Supraorbital Nerve Blockade Methods at Treatment of Acute Migraine Att NCT04491474 | Dr. Lutfi Kirdar Kartal Training and Research Hospital | Phase 4 |
| Terminated | Therapy for Migraine Prevention in Children 6-11 Years of Age NCT04050293 | Supernus Pharmaceuticals, Inc. | Phase 4 |
| Unknown | The Effect of Intravenous Fluid Therapy in Acute Migraine Attacks NCT04287140 | Marmara University | N/A |
| Completed | Mindfulness During COVID-19 NCT04319445 | Wake Forest University Health Sciences | N/A |
| Completed | Cognitive Function and Autonomic Regulation in Patients With Migraine NCT04272229 | Fortaleza University | N/A |
| Unknown | HD-EEG Connectivity Changes in Migraine Patients Undergoing Treatment With Anti-CGRP mAbs NCT06155123 | IRCCS National Neurological Institute "C. Mondino" Foundation | — |
| Active Not Recruiting | Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Migraine NCT04069897 | St. Olavs Hospital | Phase 3 |
| Completed | Assessment of Prolonged Safety and tOLerability of in Migraine Patients in a Long-term OpeN-label Study NCT04084314 | Novartis Pharmaceuticals | Phase 4 |
| Completed | Association Between Chronic Headache and Back Pain With Childbirth NCT04091321 | Stanford University | — |
| Unknown | Migraine Abortive Treatment NCT05048914 | Bnai Zion Medical Center | — |
| Completed | A Functional MRI Study on Erenumab Treatment Effects in Episodic Migraine Patients NCT03977649 | Novartis Pharmaceuticals | Phase 4 |
| Completed | Acupuncture as Migraine Prophylaxis in Reducing Frequency, Duration and Intensity of Migraine With Minimum Acu NCT04509141 | Indonesia University | N/A |
| Terminated | Predicting Migraine Attacks Based on Environmental and Behavioral Changes as Detected From the Smartphone NCT03762902 | Lifegraph Ltd. | — |
| Completed | A Study of Home-Delivered Neurostimulation for Migraine NCT03874351 | MJHS Institute for Innovation in Palliative Care | N/A |
| Terminated | Efficacy of a Novel App-based Migraine Treatment Platform - a Pilot Study NCT04106505 | Norwegian University of Science and Technology | N/A |
| Withdrawn | 4-Aminopyridine, Atenolol, or Placebo in Patients With Vestibular Migraine NCT03578354 | Massachusetts Eye and Ear Infirmary | Phase 2 |
| Unknown | Defining the Sympathetic Skin Response of Migraineurs in the Facial Area NCT03772860 | Hillel Yaffe Medical Center | — |
| Completed | Non-invasive Vagus Nerve Stimulation for the Prevention of Migraines NCT03716505 | ElectroCore INC | N/A |
| Unknown | Osteopathic Manipulative Treatment and Migraine Headaches NCT04976985 | St. Luke's Hospital, Pennsylvania | N/A |
| Completed | Mind and Body Approaches to Pain Reduction in Youth With Migraine NCT03472092 | Children's Hospital Medical Center, Cincinnati | Phase 2 |
| Completed | Stroke-like Migraine Attacks After Radiation Treatment (SMART) Syndrome Language Intervention NCT03662295 | Quality Living, Inc. | — |
| Completed | Day to Day Variation of Pressure Pain Threshold and Muscle Hardness NCT03632928 | Danish Headache Center | — |
| Completed | Transnasal Therapy for Acute Migraine Attack NCT04129567 | Johns Hopkins University | N/A |
| Unknown | The Relationship Between Right-to-left Shunt and Brain White Matter Lesions in Patients With Migraine NCT03418766 | The First Hospital of Jilin University | — |
| Unknown | Testing myWHI: Online Self-help Programs for Headaches NCT03504150 | IWK Health Centre | N/A |
| Completed | "Follow the Sutures". A New Procedure for Injection of Botulinum Toxin for Chronic Migraine NCT03543254 | Norwegian University of Science and Technology | Phase 2 |
| Completed | Sofusa System With Sumatriptan (KC5010) Phase 1 Dose Escalation Safety and PK Study (KCC-SMT-002) NCT03229798 | Sorrento Therapeutics, Inc. | Phase 1 |
| Withdrawn | Open Label Study of BOTOX® (Botulinum Toxin Type A) as Headache Prophylaxis in Chinese Patients With Chronic M NCT03193359 | Allergan | Phase 3 |
| Unknown | Topical Bimatoprost in the Treatment of Migraine NCT03419715 | Manistee Partners | Phase 2 |
| Completed | MigraineManager: An Individualized Self-Management Tool for Adolescents With Migraine NCT03157739 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | A Study of Lasmiditan in Participants With Migraine NCT03247790 | Eli Lilly and Company | Phase 1 |
| Completed | Muscle Tenderness and Hardness in Migraine Patients NCT03626805 | Danish Headache Center | — |
| Withdrawn | BOTOX® (Botulinum Toxin Type A) as Headache Prophylaxis in Chinese Participants With Chronic Migraine NCT03193346 | Allergan | Phase 3 |
| Unknown | Treatment of Chronic Migraine Headaches. NCT03220113 | Corona Doctors Medical Clinics, Inc. | Phase 1 / Phase 2 |
| Completed | Integrative Migraine Pain Alleviation Through Chiropractic Therapy NCT03177616 | Harvard University Faculty of Medicine | N/A |
| Unknown | Magnesium, Partenium, Andrographis, Co-enzyme Q10 and Riboflavin (PACR) in Migraine Prophylaxis NCT03190044 | University of Roma La Sapienza | N/A |
| Completed | Effectiveness of Onabotulinumtoxin A (Botox) in Pediatric Patients Experiencing Migraines: A Study in the Pedi NCT03055767 | University of California, Irvine | Phase 2 |
| Completed | Continue or Stop Applying Wet Cupping (Al-Hijamah) in Migraine NCT03479060 | Karabuk University | N/A |
| Terminated | Understanding the Pathophysiology of Migraine Pain NCT03026101 | Montefiore Medical Center | N/A |
| Completed | A Ketogenic Diet Acts on Cortical But Not Subcortical Responsivity in Migraineurs NCT03775252 | University of Roma La Sapienza | N/A |
| Completed | CBT Depression Intervention for Co-Occurring Chronic Headache NCT02870725 | University of Georgia | N/A |
| Completed | Evaluation of ALD403 (Eptinezumab) in the Prevention of Chronic Migraine NCT02974153 | Alder Biopharmaceuticals, Inc. | Phase 3 |
| Completed | Individualized Prediction of Migraine Attacks Using a Mobile Phone App and Fitbit NCT02910921 | Second Opinion Health | — |
| Completed | Intervention for Sleep and Pain in Youth NCT03137147 | Seattle Children's Hospital | N/A |
| Completed | Biomarker Study in Participants With Migraine NCT02766517 | Eli Lilly and Company | EARLY_Phase 1 |
| Completed | The Role of Osteopathic Manipulation in the the Management of Post-traumatic Migraine NCT03588364 | University of California, San Diego | N/A |
| Withdrawn | Greater Occipital Nerve (GON) Block Effectivity in the Treatment of Chronic Migraine: 6 Months Follow up NCT02578719 | Bozok University | Phase 4 |
| Unknown | Transcranial Direct Current Simulation in Chronic Migraine NCT02817139 | Federal University of Paraíba | Phase 1 / Phase 2 |
| Unknown | Optimized tDCS for the Treatment of Migraine NCT02562222 | Universidade Federal de Pernambuco | Phase 2 |
| Withdrawn | Resting-state Functional Connectivity Changes During Migraine Treatment NCT03484871 | Samsung Medical Center | — |
| Unknown | Buccal Prochlorperazine Versus Intravenous Prochlorperazine for Migraine Headaches, a RCT NCT02779959 | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Phase 3 |
| Completed | Efficacy of Proprioceptive Neuromuscular Facilitation in Pain Relief NCT02549885 | Universidade Federal de Pernambuco | N/A |
| Unknown | tDCS for the Treatment of Migraine NCT02562196 | Universidade Federal de Pernambuco | Phase 2 |
| Terminated | Interventional Testing of Gene-environment Interactions Via the Verifomics Mobile Application NCT02758990 | Verifomics LLC | N/A |
| Completed | tDCS in Chronic Migraine With Medication Overuse (Edisom) NCT04228809 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | N/A |
| Completed | An Open-label, Long-term, Safety Study of Lasmiditan for the Acute Treatment of Migraine NCT02565186 | Eli Lilly and Company | Phase 3 |
| Completed | IV Haloperidol for the Treatment of Headache in the ED NCT02747511 | Western Michigan University School of Medicine | Phase 4 |
| Completed | A Multicenter Assessment of ALD403 in Frequent Episodic Migraine NCT02559895 | Alder Biopharmaceuticals, Inc. | Phase 3 |
| Completed | Patient Reported Outcomes in Patients With Chronic Migraine Treated With BOTOX® NCT02502123 | Allergan | — |
| Completed | Effects of the Visual Stimulation on the Motor and Visual Cortex in Migraneurs With and Without Aura NCT02564822 | Universidade Federal de Pernambuco | — |
| Completed | Sustained onabotulinumtoxinA Therapeutic Benefits in Patients With Chronic Migraine NCT03606356 | Corfu Headache Clinic | Phase 4 |
| Completed | 1H Magnetic Resonance Spectroscopy in Migraine Patients NCT04220606 | Leiden University Medical Center | N/A |
| Completed | How Can we Treat Photophobia in Migraine NCT05369910 | Medical University of Vienna | N/A |
| Completed | Botox Injection in Treatment of Chronic Migraine NCT02259075 | Norwegian University of Science and Technology | Phase 1 / Phase 2 |
| Completed | Intravenous Metoclopramide in the Acute Treatment of Migraine: A Double-blind, Randomized, Placebo-controlled NCT02314351 | Kocaeli University | Phase 4 |
| Completed | A Multicenter Assessment of ALD403 in Chronic Migraine NCT02275117 | Alder Biopharmaceuticals, Inc. | Phase 2 |
| Completed | Greater Occipital and Supraorbital Nerve Blockade in Migraine Patients NCT03435185 | Dr. Lutfi Kirdar Kartal Training and Research Hospital | N/A |
| Terminated | Trial of Nortriptyline and Topiramate in the Initial Treatment of Vestibular Migraine NCT02169830 | St. Louis University | N/A |
| Completed | Efficacy and Safety Study of BOTOX® Compared to Topiramate for the Prevention of Chronic Migraine in Adults NCT02191579 | Allergan | Phase 4 |
| Completed | A Safety and Efficacy Study of BOTOX® in Korean Adults With Chronic Migraine NCT02147561 | Allergan | Phase 4 |
| Completed | Nutrition for Migraine Prevention NCT02012790 | University of North Carolina, Chapel Hill | N/A |
| Completed | Chronic Pain Risk Associated With Menstrual Period Pain NCT02214550 | Endeavor Health | Phase 4 |
| Completed | A Study of LY2951742 in Healthy Japanese and Caucasian Participants NCT02104765 | Eli Lilly and Company | Phase 1 |
| Completed | A Retrospective Chart Review to Evaluate Diagnosis and Treatment of Chronic Migraine and Headache NCT01946126 | Allergan | — |
| Terminated | Thin Film Spectacle Coatings to Reduce Light Sensitivity and Headaches in Child and Adolescent Patients With M NCT01942486 | University of Utah | N/A |
| Terminated | Occipital Nerve Stimulation (ONS) for Migraine: OPTIMISE NCT01775735 | Boston Scientific Corporation | N/A |
| Completed | Thin Film Spectacle Coatings to Reduce Light Sensitivity and Headaches in Patients With Migraine NCT01828684 | Bradley Katz | N/A |
| Completed | A Study Using Botulinum Toxin Type A as Headache Prophylaxis in Adolescents With Chronic Migraine NCT01662492 | Allergan | Phase 3 |
| Completed | An Observational Study of BOTOX® as Headache Prophylaxis for Chronic Migraine NCT01686581 | Allergan | — |
| Withdrawn | The Impact of Triptan and Doxycycline on Neuroinflammatory Biomarkers in Acute Migraine NCT01653522 | The Cleveland Clinic | N/A |
| Completed | Chronic Migraine Epidemiology and Outcomes Study NCT01648530 | Allergan | — |
| Completed | Safety and Efficacy of Botulinum Toxin Type A (BOTOX®) to Treat Chronic Migraine in Korea NCT01976611 | Allergan | — |
| Terminated | The Childhood and Adolescent Migraine Prevention Study NCT01581281 | Children's Hospital Medical Center, Cincinnati | Phase 3 |
| Completed | Safety Tolerability and Pharmacokinetics of ALD403 NCT01579383 | Alder Biopharmaceuticals, Inc. | Phase 1 |
| Unknown | The Efficacy and Safety of Intra-oral Topical Ketoprofen for the Treatment of Acute Migraine NCT01228552 | Behar, Caren, M.D. | Phase 3 |
| Completed | A Long-term Efficacy, Safety, and Tolerability Study of BOTOX® in Patients With Chronic Migraine NCT01516892 | Allergan | Phase 4 |
| Completed | Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study Of PF-04427429 In Healthy Women Volunteers NCT01511497 | Pfizer | Phase 1 |
| Completed | BOTOX® Prophylaxis in Patients With Chronic Migraine NCT01432379 | Allergan | — |
| Completed | A Combination Product of Sumatriptan and Naproxen Sodium Versus Single-entity Oral Triptans: An Analysis of Re NCT01381523 | GlaxoSmithKline | — |
| Completed | Impact of Migraine on Work Productivity in Patients Treated With a Combination Product Containing Sumatriptan NCT01381497 | GlaxoSmithKline | — |
| Completed | Study to Evaluate the Efficacy and Safety of Oral Sumatriptan for the Acute Treatment of Migraine in Children NCT00963937 | GlaxoSmithKline | Phase 3 |
| Completed | Non-steroidal Anti-inflammatory Drugs Alone or With a Triptan and Reports of Transition From Episodic to Chron NCT01435941 | GlaxoSmithKline | — |
| Completed | Effect of Metoclopramide Versus Sumatriptan for Emergency Department Treatment of Migraine Headache NCT01791400 | Isfahan University of Medical Sciences | Phase 2 |
| Completed | Dose-ranging Study of Oral COL-144 in Acute Migraine Treatment NCT00883051 | Eli Lilly and Company | Phase 2 |
| Completed | A Pilot Study of Migraine and Appetite Behaviour in Children NCT00930852 | Alder Hey Children's NHS Foundation Trust | — |
| Completed | Treximet ™ Pharmacy Budget Impact Model Database Validation Study NCT01332500 | GlaxoSmithKline | — |
| Completed | MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use NCT01050465 | University of Missouri-Columbia | N/A |
| Completed | Special Drug Use Investigation for AMERGE® Tablet (Long-term) NCT01332383 | GlaxoSmithKline | — |
| Completed | Drug Use Investigation for AMERGE (Naratriptan Hydrochloride) Tablet NCT01376193 | GlaxoSmithKline | — |
| Completed | An Open-Label Study to Evaluate the Safety of NP101 in the Treatment of Acute Migraine Over Twelve Months NCT00806546 | NuPathe Inc. | Phase 3 |
| Completed | An Open-Label Study to Evaluate the Safety of NP101 in the Treatment of Acute Migraine Over 12 Months NCT00792103 | NuPathe Inc. | Phase 3 |
| Completed | The Efficacy and Tolerability of NP101 Patch in the Treatment of Acute Migraine NCT00724815 | NuPathe Inc. | Phase 3 |
| Completed | Topiramate and Cerebrovascular Response in Migraineurs NCT02424318 | SMG-SNU Boramae Medical Center | Phase 4 |
| Completed | Migraine Study in Adolescent Patients NCT00843024 | GlaxoSmithKline | Phase 3 |
| Completed | A Pharmacokinetic Study to Evaluate TREXIMET in Adolescents With Migraine and Healthy Subjects Administered at NCT00989625 | GlaxoSmithKline | Phase 1 |
| Completed | Phase I, Open Label, Single-Dose, Four Way Crossover Study to Compare the PK of NP101 With Oral Imitrex® (50mg NCT00723983 | NuPathe Inc. | Phase 1 |
| Completed | A Study to Determine the Effect of Sumatriptan and Naproxen Sodium Combination Tablet, Sumatriptan Tablet, and NCT00792636 | GlaxoSmithKline | Phase 4 |
| Completed | Relative Bioavailability of a Single Dose of BI 44370 Tablet During and Between Migraine Attacks NCT00743015 | Boehringer Ingelheim | Phase 1 |
| Completed | Prevention Study in Adult Patients Suffering From Migraine Headaches NCT00742209 | XenoPort, Inc. | Phase 2 |
| Completed | BI 44370 TA in Acute Migraine Attack NCT00751803 | Boehringer Ingelheim | Phase 2 |
| Completed | Phase 3 Study of MAP0004 in Adult Migraineurs NCT00623636 | Allergan | Phase 3 |
| Completed | Phase I Open Label Single-Dose Study to Compare the Pharmacokinetics of NP101 Healthy Volunteers NCT00720018 | NuPathe Inc. | Phase 1 |
| Completed | An Open-label, Randomized, 3-period Crossover Study to Evaluate Sumatriptan Pharmacokinetics for a TREXIMA™ (S NCT00875784 | GlaxoSmithKline | Phase 1 |
| Completed | Telcagepant (MK-0974) Treatment of Migraine in Participants With Stable Vascular Disease (MK-0974-034) NCT00662818 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | TREXIMET® Versus Butalbital-containing Combination Medications for the Acute Treatment of Migraine in Adults NCT00573170 | GlaxoSmithKline | Phase 3 |
| Completed | Drug Study in Pediatric Subjects With Migraines (MK0462-083 AM1) NCT00604812 | Organon and Co | Phase 1 |
| Completed | Study to Evaluate the Safety, Tolerability, and Blood Pressure Effect of an Oral Dose of Sumatriptan Alone and NCT00701389 | Merck Sharp & Dohme LLC | Phase 1 |
| Completed | A Study of Gastric Delay in Migraine Patients (3207-003) NCT00548353 | Merck Sharp & Dohme LLC | Phase 1 |
| Completed | Long-Term Safety of Treximet (Sumatriptan/Naproxen Sodium) for Migraine in Adolescents NCT00488514 | GlaxoSmithKline | Phase 3 |
| Unknown | Vestibular System in Migrainous Vertigo Patients NCT00901953 | University of Bergen | — |
| Withdrawn | Efficacy of Pregabalin in Migraine Prevention NCT00447369 | Hospital Militar del General Luis Felipe Brieba Aran | Phase 3 |
| Unknown | Efficacy and Safety Clinical Trial of Intranasal AST-726 for the Prevention of Migraine NCT00285402 | Ariston Pharmaceuticals, Inc. | Phase 2 |
| Completed | Caffeine/Propranolol Intervention for Acute Migraine NCT01080677 | Stanford University | Phase 2 |
| Completed | A Study of Combination Product (Sumatriptan Succinate and Naproxen Sodium) in Migraine Subjects Who Report Poo NCT00382993 | GlaxoSmithKline | Phase 3 |
| Completed | A Study of Combination Product (Sumatriptan Succinate and Naproxen Sodium) in Migraine Subjects Who Report Poo NCT00383162 | GlaxoSmithKline | Phase 3 |
| Completed | TREXIMA and RELPAX Gastric Scintigraphy Inside and Outside a Migraine NCT00385008 | GlaxoSmithKline | Phase 3 |
| Completed | Lippia Alba for Migraine Prophylaxis and Treatment NCT01259947 | Fabio Carmona | Phase 2 |
| Completed | Study Of Sumatriptan Succinate Injection Kit In Patients With Migraine or Cluster Headache In Japan NCT00356603 | GlaxoSmithKline | Phase 3 |
| Completed | Menstrual Migraine Treatment With TREXIMET (Formerly Known as TREXIMA) NCT00329355 | GlaxoSmithKline | Phase 3 |
| Completed | Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as TREXIMA, for Menstrual Migraine in Women With Dysmen NCT00329459 | GlaxoSmithKline | Phase 3 |
| Completed | A Study Using Botulinum Toxin Type A as Headache Prophylaxis for Migraine Patients With Frequent Headaches NCT00168428 | Allergan | Phase 3 |
| Completed | A Study Using Botulinum Toxin Type A as Headache Prophylaxis for Migraine Patients With Frequent Headaches NCT00156910 | Allergan | Phase 3 |
| Unknown | American Migraine Prevention Study NCT00363506 | Dynamic Health Resources | Phase 4 |
| Completed | An Adaptive Design Trial Of GW274150 In The Treatment Of Acute Migraine NCT00319137 | GlaxoSmithKline | Phase 2 |
| Terminated | ESCAPE Migraine Trial NCT00267371 | Abbott Medical Devices | Phase 3 |
| Completed | Study Of Treximet, Formerly Known as Trexima, In The Acute Treatment Of Multiple Migraine Attacks NCT00240617 | GlaxoSmithKline | Phase 3 |
| Completed | Use Of GW274150 In The Prophylactic Treatment Of Migraine NCT00242866 | GlaxoSmithKline | Phase 2 |
| Completed | Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as Trexima, In The Acute Treatment Of Multiple Migraine NCT00240630 | GlaxoSmithKline | Phase 3 |
| Completed | An Observational Study Evaluating the Safety of Topiramate for the Prevention of Migraine NCT00297336 | Janssen Cilag Pharmaceutica S.A.C.I., Greece | — |
| Completed | Sumatriptan and Naratriptan Pregnancy Registry NCT01059604 | GlaxoSmithKline | — |
| Completed | Drug Use Investigation for IMIGRAN Tablet NCT01376141 | GlaxoSmithKline | — |
| Completed | Efficacy, Safety, Tolerability and Pharmacokinetics of BIBN 4096 BS Versus Placebo in the Treatment of a Singl NCT02198339 | Boehringer Ingelheim | Phase 2 |
| Completed | Efficacy and Tolerability of Metamizol in Patients With Episodic Moderate Headache NCT02183220 | Boehringer Ingelheim | Phase 3 |
| Completed | Acetylsalicylic Acid (ASA) + Paracetamol + Caffeine Combination Compared With ASA + Paracetamol as Well as ASA NCT02183688 | Boehringer Ingelheim | Phase 3 |
| Completed | Long-Term Exposure to Rizatriptan 5-mg and 10-mg Oral Tablet (Combined Extension Protocols MK-0462-022, MK-046 NCT01286207 | Organon and Co | Phase 3 |