NCT00447369

Efficacy of Pregabalin in Migraine Prevention

• Status: Withdrawn
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Hospital Militar del General Luis Felipe Brieba Aran · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the efficacy and safety of pregabalin in comparison with sodium valproate in migraine prevention with a randomized blinded crossover study.

Detailed description

The anticonvulsants are effective in the treatment of migraine prevention. The sodium valproate has demonstrated to be effective as monotherapy for migraine prevention in placebo-controlled trials. Besides, other new drugs like gabapentin have been used in the prevention of migraine with a good level of evidence. The pregabalin is an anticonvulsant that has not been proved to use in migraine prevention and it has a similar action mechanisms of the gabapentin. The purpose of this study is the comparison of the effect of pregabalin and sodium valproate in migraine prevention in a randomized blinded crossover study.

Conditions

• Migraine Disorders

Interventions

Type	Name	Description
DRUG	Pregabalin
DRUG	sodium valproate

Timeline

• Start date: 2007-05-01
• Completion: 2008-03-01
• First posted: 2007-03-14
• Last updated: 2008-05-09

Locations

1 site across 1 country: Chile