| Recruiting | Partial Pleurectomy (Surgery) for Unresectable Pleural Mesothelioma NCT07126509 | University of Chicago | N/A |
| Recruiting | First Line Sintilimab Combined With Anlotinib and Platinum Doublet Chemotherapy in Malignant Pleural Mesotheli NCT05188859 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Phase 2 |
| Recruiting | SW-682 in Advanced Solid Tumors NCT06251310 | SpringWorks Therapeutics, Inc. | Phase 1 |
| Terminated | NM32-2668 in Adult Patients With Selected Advanced Solid Tumors NCT06299163 | Numab Therapeutics AG | Phase 1 |
| Recruiting | A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With So NCT06051695 | A2 Biotherapeutics Inc. | Phase 1 / Phase 2 |
| Not Yet Recruiting | Clinical Study to Evaluate Safety and Dosing of CA9hu-1 in Patients With Advanced Solid Tumours NCT05698238 | Mabpro, a.s. | Phase 1 |
| Unknown | Treatment Pleural Carcinosis of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin Administration NCT06281860 | Dr Jean Yannis PERENTES | Phase 1 |
| Recruiting | A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma NCT06057935 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Recruiting | HTL0039732 in Participants With Advanced Solid Tumours NCT05944237 | Cancer Research UK | Phase 1 / Phase 2 |
| Recruiting | First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis. NCT06946498 | National and Kapodistrian University of Athens | N/A |
| Recruiting | SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma NCT05568680 | Verismo Therapeutics | Phase 1 |
| Unknown | Immunological Variables Associated to ICI Toxicity in Cancer Patients NCT05429866 | Jules Bordet Institute | Phase 2 |
| Completed | Niraparib Efficacy in Patient With Unresectable Mesothelioma NCT05455424 | University Hospital Southampton NHS Foundation Trust | Phase 2 |
| Active Not Recruiting | A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer NCT05451849 | TCR2 Therapeutics | Phase 1 / Phase 2 |
| Completed | ......SMARTEST Trial...... NCT05380713 | University Health Network, Toronto | Phase 2 |
| Unknown | Molecular, Pathologic Intra Tumoral Heterogeneity in Malignant Pleural Mesothelioma NCT04823741 | Hospices Civils de Lyon | — |
| Completed | A Study to Evaluate Nivolumab in Combination With Ipilimumab Versus Pemetrexed With Cisplatin or Carboplatin f NCT05136677 | Bristol-Myers Squibb | Phase 2 |
| Completed | A Study of Yervoy and Opdivo Combination Therapy in Participants With Unresectable Advanced/Recurrent Malignan NCT05324436 | Bristol-Myers Squibb | — |
| Recruiting | Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing NCT04981119 | A2 Biotherapeutics Inc. | — |
| Withdrawn | A Pilot Study to Explore the Role of Gut Flora in Metastatic Mesothelioma NCT04214015 | ProgenaBiome | — |
| Active Not Recruiting | Pembrolizumab Plus Autologous Dendritic Cell Vaccine in Patients with PD-L1 Negative Advanced Mesothelioma Who NCT03546426 | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS | Phase 1 |
| Recruiting | A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas NCT04104776 | Novartis Pharmaceuticals | Phase 1 / Phase 2 |
| Suspended | A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease NCT04031469 | ProgenaBiome | — |
| Active Not Recruiting | Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer NCT03907852 | TCR2 Therapeutics | Phase 1 / Phase 2 |
| Unknown | Mesothelioma Stratified Therapy (MiST) : A Multi-drug Phase II Trial in Malignant Mesothelioma NCT03654833 | University of Leicester | Phase 2 |
| Terminated | Phase II Nivolumab and Ramucirumab for Patients With Previously-Treated Mesothelioma NCT03502746 | Arkadiusz Z. Dudek, MD | Phase 2 |
| Terminated | Combination of Immunotherapy and Hyperthermia in Advanced Malignant Mesothelioma NCT03393858 | Capital Medical University | Phase 1 / Phase 2 |
| Terminated | Study of the Safety and Efficacy of Amatuximab in Combination With Pemetrexed and Cisplatin in Subjects With U NCT02357147 | Morphotek | Phase 2 |
| Completed | Combination of Gemcitabine and Imatinib Mesylate in Pemetrexed-pretreated Patients With Pleural Mesothelioma NCT02303899 | Istituto Clinico Humanitas | Phase 2 |
| Completed | 11C-Methionine PET/CT Imaging in Patients Affected by Malignant Pleural Mesothelioma (MPM) NCT02519049 | Istituto Clinico Humanitas | — |
| Completed | Malignant Mesothelioma - Can we Improve Quality of Life NCT03068117 | Portsmouth Hospitals NHS Trust | N/A |