| Not Yet Recruiting | Prediction of Infectious Agents in the Biofire® FilmArray bioMérieux Meningitis/Encephalitis Panel Based on Cl NCT07432113 | Federal University of Health Science of Porto Alegre | N/A |
| Not Yet Recruiting | Neuroendoscopic Surgery With Ommaya Reservoir Implantation vs. Burr Hole Drainage for Infantile Postmeningitis NCT07320599 | Shengjing Hospital | — |
| Recruiting | Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective NCT07358910 | Institut Pasteur du Cambodge | — |
| Recruiting | Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral Pathologi NCT07332234 | Spitalul Clinic de Boli Infecțioase și tropicale "Dr. Victor Babeș" | — |
| Not Yet Recruiting | Acute Treatment and Long-term Assessment of Adult Infectious Meningitis NCT07027475 | Hospital Israelita Albert Einstein | — |
| Not Yet Recruiting | Prospective Clinical Registry of Acute Treatment and Long-term Assessment of Children Meningitis NCT07062445 | Hospital Israelita Albert Einstein | — |
| Active Not Recruiting | A Phase 3 Study to Assess the Immune Response And Safety Of Rmenb+Omv Nz In Primed Healthy Participants (10 To NCT06995430 | GlaxoSmithKline | Phase 3 |
| Active Not Recruiting | Clinical Performance of QIAstat-Dx® Meningitis/Encephalitis (ME) Panel Plus NCT06820060 | QIAGEN Gaithersburg, Inc | — |
| Active Not Recruiting | A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant Women NCT06592586 | Minervax ApS | Phase 2 / Phase 3 |
| Not Yet Recruiting | Neonatal Comfort Seat Allowing Safe Lumbar Puncture and Minimizing Failure: a Randomized Controlled Trial NCT06811428 | Joel Cox | N/A |
| Completed | ACTIVATE in Public Housing NCT06075732 | Charles Drew University of Medicine and Science | N/A |
| Completed | Analysis of Cerebrospinal Fluid in Patients With Cerebral Toxoplasmosis at CHSD (2004-2024) NCT07044037 | Centre Hospitalier de Saint-Denis | — |
| Recruiting | Evaluation of the Levels of Calcitonin Gene-related Peptide and Substance P NCT06510751 | Melike Cengiz | — |
| Recruiting | Bedside Ultrasound on the Effectiveness of Lumbar Puncture in Children. NCT06584864 | Medical University of Warsaw | N/A |
| Enrolling By Invitation | Phase II Clinical Study of Contezolid for the Treatment of Tuberculous Meningitis NCT06811025 | Beijing Chest Hospital | Phase 1 / Phase 2 |
| Completed | Artificial Intelligence-powered Virtual Assistant for Emergency Triage in Neurology NCT06334796 | Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia | EARLY_Phase 1 |
| Unknown | Improving Diagnosis and Prediction of Outcome in Patients With Severe Disorders of Consciousness NCT06283901 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Unknown | Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section NCT05637645 | Bahawal Victoria Hospital Bahawalpur | N/A |
| Recruiting | Meningitis: Burden, Causes, Screening and Prevention in Rural Northern Uganda NCT05496673 | University of Rochester | N/A |
| Enrolling By Invitation | Evolving Diagnostic Approaches to Undocumented Lymphocytic Meningitis and Meningoencephalitis NCT07186881 | Central Hospital, Nancy, France | — |
| Completed | Febrile Infant Diagnostic Assessment and Outcome Study NCT05259683 | Queen's University, Belfast | — |
| Unknown | Regulating Emotions and Behaviors After Brain Injury NCT05393492 | University Hospital, Strasbourg, France | N/A |
| Completed | Meningococcal Serogroup ACYWX Conjugate Vaccine in Comparison With MenACWY-TT Conjugate Vaccine NCT05093829 | Emory University | Phase 3 |
| Unknown | Validation of a Predictive Rule for the Diagnosis of Viral Meningitis in Adult Emergency Departments NCT05062642 | Centre Hospitalier le Mans | — |
| Unknown | The Clinical Character，Risk and Prognosis of Post-neurosurgical Intracranial Infection With Different Pathogen NCT04917380 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Unknown | Optimal Encephalitis/Meningitis Roadmap Via Precise Diagnosis and Treatment NCT04946682 | Wen-hong Zhang | N/A |
| Unknown | Establishment of Prevention and Control System of Central Nervous System Infection NCT04722328 | Xuanwu Hospital, Beijing | — |
| Completed | BIGlobal Intervention Study: Improving Diagnosis and Management of Suspected Brain Infections Globally NCT04190303 | University of Liverpool | — |
| Completed | Host RNA Profiles to Detect Infections in Young Infants NCT04823026 | Rigshospitalet, Denmark | — |
| Completed | Persistence of Immunogenicity Following Reduced PCV Dosing Schedules in South African Children NCT04275284 | University of Witwatersrand, South Africa | — |
| Completed | The Effect of Supraglottic and Oropharyngeal Decontamination on the Incidence of Ventilator-associated Pneumon NCT04325685 | Northern State Medical University | N/A |
| Completed | Epidemiological, Clinical, Microbiological and Outcome Description of Patients With Klebsiella sp Meningitis NCT03967210 | Fondation Hôpital Saint-Joseph | — |
| Completed | Brazil ICU Encephalitis Surveillance NCT05370573 | D'Or Institute for Research and Education | — |
| Completed | Paediatric Infections Point-Of-Care NCT03900091 | Karolinska Institutet | — |
| Completed | Repeat Lumbar Puncture at 24 Versus 48 Hours After Traumatic Lumbar Puncture in Neonates NCT04794881 | Post Graduate Institute of Medical Education and Research, Chandigarh | N/A |
| Completed | Neurology Inpatient Clinical Education Trial NCT03826056 | Dartmouth-Hitchcock Medical Center | N/A |
| Completed | Pediatric Infectious Disease Precision Medicine Using Sequencing Evaluation of CSF NCT03796546 | IDbyDNA, Inc. | — |
| Unknown | Maternal Immunization With MenAfriVac™ NCT03746665 | London School of Hygiene and Tropical Medicine | Phase 3 |
| Withdrawn | Increasing Healthcare Engagement Via Routine Vaccination Among Young Black Men Who Have Sex With Men NCT03445416 | Ann & Robert H Lurie Children's Hospital of Chicago | N/A |
| Completed | The Effectiveness and Safety of Human Lumbar Puncture Assist Device (LPat) NCT03710278 | Spartanburg Regional Healthcare System | — |
| Completed | Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanc NCT03378258 | Belfast Health and Social Care Trust | — |
| Completed | Treatment With Tamoxifen in Cryptococcal Meningitis NCT03112031 | Oxford University Clinical Research Unit, Vietnam | Phase 2 |
| Completed | Combined Intracerebral and Jugular Bulb Microdialysis NCT03314779 | Odense University Hospital | — |
| Completed | Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Toddlers NCT02955797 | Sanofi Pasteur, a Sanofi Company | Phase 3 |
| Completed | Study of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Administered in Children Aged 2 to 9 NCT03077438 | Sanofi Pasteur, a Sanofi Company | Phase 3 |
| Completed | Reduced PCV Dosing Schedules in South African Infants NCT02943902 | University of Witwatersrand, South Africa | Phase 3 |
| Completed | Hypovitaminosis D in Neurocritical Patients NCT02881957 | University of Utah | Phase 2 / Phase 3 |
| Unknown | Immunogenicity and Safety of Meningococcal Groups A and C and Haemophilus b Conjugate Vaccine in Infants 2 to NCT02919293 | Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd | Phase 1 / Phase 2 |
| Completed | Postmarketing Surveillance Study for Use of Menactra® in the Republic of Korea NCT02864927 | Sanofi Pasteur, a Sanofi Company | Phase 4 |
| Completed | Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Adults 56 Year NCT02842866 | Sanofi Pasteur, a Sanofi Company | Phase 3 |
| Completed | Immune Lot Consistency, Immunogenicity, and Safety of an Investigational Quadrivalent Meningococcal Conjugate NCT02842853 | Sanofi Pasteur, a Sanofi Company | Phase 3 |
| Completed | Safety of a Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine in Hea NCT02640404 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Completed | Precision Diagnosis of Acute Infectious Diseases; Neuroinflammatory Cohort NCT02910037 | University of California, San Francisco | N/A |
| Completed | Immunogenicity and Safety of a Booster Dose of an Investigational Quadrivalent Meningococcal Conjugate Vaccine NCT02752906 | Sanofi Pasteur, a Sanofi Company | Phase 3 |
| Withdrawn | Host-pathogen Interactions in Meningococcal Disease: Finding the Key That Fits the Lock NCT02727465 | Public Health England | — |
| Completed | Observational Safety Study of Menactra® Administered Under Standard Health Care Practice in the Russian Federa NCT02699840 | Sanofi Pasteur, a Sanofi Company | — |
| Completed | Neurologic Manifestations of the Arbovirus Infection in Colombia NCT03206541 | Johns Hopkins University | — |
| Completed | Persistence of Bactericidal Antibodies in Adults Who Received a Booster Dose of Menactra® Approximately 4 Year NCT02633787 | Sanofi Pasteur, a Sanofi Company | Phase 4 |
| Completed | Immunogenicity and Safety of Two-Dose Series of Menactra® in Japanese Healthy Adult Subjects NCT02591290 | Sanofi Pasteur, a Sanofi Company | Phase 4 |
| Completed | Penetration of Ceftaroline Into Cerebrospinal Fluid(CSF) NCT02806882 | Centre Hospitalier Universitaire Dijon | Phase 1 |
| Unknown | PatientSpot Formerly Known as ArthritisPower NCT03840928 | Global Healthy Living Foundation | — |
| Completed | Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Toddle NCT03205358 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Recruiting | Central Nervous System Infections in Denmark NCT03418441 | Aalborg University Hospital | — |
| Completed | Diagnostic Performance of Clinical Signs Patients Suspected of Meningitis to Emergencies NCT02841254 | Nantes University Hospital | — |
| Completed | Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Adoles NCT02199691 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Completed | Investigating the Immune Response to 4CMenB in Infants NCT02080559 | University of Oxford | Phase 4 |
| Completed | Stem Cell Transplantation In-patient With Neurological Sequelae Due to Encephalitis or Meningitis NCT04080921 | Vinmec Research Institute of Stem Cell and Gene Technology | Phase 1 / Phase 2 |
| Completed | Understanding Pneumococcal Carriage and Disease NCT01996007 | University of Oxford | — |
| Completed | Feeding Bovine Colostrum to Preterm Infants NCT02054091 | Per Torp Sangild | N/A |
| Completed | Immunogenicity and Safety of Group A, C, Y and W135 Meningococcal Polysaccharide Vaccine NCT02003313 | Beijing Minhai Biotechnology Co., Ltd | Phase 3 |
| Completed | Immunogenicity and Safety of Meningococcal (A, C, Y and W135) Conjugate Vaccine NCT02003495 | Beijing Minhai Biotechnology Co., Ltd | Phase 3 |
| Completed | Pertussis and Meningitis C Concomitant Vaccination in Adolescents NCT02526394 | Public Health England | Phase 4 |
| Completed | Immunogenicity and Safety of Menactra® Vaccine in Subjects Aged 9 to 23 Months in India and in the Russian Fed NCT01890759 | Sanofi Pasteur, a Sanofi Company | Phase 3 |
| Completed | Nervous System Infections Among Patients With Febrile Seizure NCT01694524 | Hôpital Armand Trousseau | — |
| Completed | Improving the Diagnosis of Meningitis in Emergency Rooms NCT02858661 | Assistance Publique Hopitaux De Marseille | N/A |
| Completed | Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days of Age With Probable and Confirmed Meningiti NCT01554124 | PENTA Foundation | Phase 1 / Phase 2 |
| Completed | Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary Care NCT02024282 | KU Leuven | N/A |
| Completed | Understanding the Immune Response to Two Different Meningitis Vaccines NCT01593514 | University of Oxford | Phase 4 |
| Completed | Pharmacological Study of High Doses of Ceftriaxone in Meningitidis NCT01745679 | Nantes University Hospital | Phase 4 |
| Completed | Study of a Quadrivalent Meningococcal Conjugate Vaccine in Subjects Aged 56 and Older NCT01732627 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Terminated | Lumbar Punctures in Neonates: Improving Success Rates and Minimizing Pain NCT01606150 | Georgetown University | N/A |
| Completed | Safety and Immunogenicity Study for Use of Menactra® Versus Adacel® in Subjects 11 to 55 Years of Age in South NCT01642589 | Sanofi Pasteur, a Sanofi Company | Phase 3 |
| Completed | Study of Menactra® in Healthy Subjects at 9 Months and Concomitantly With Pentacel® at 15 to 18 Months of Age NCT01659996 | Sanofi Pasteur, a Sanofi Company | Phase 4 |
| Completed | Phase 3 Study of A Group A, C Polysaccharide Meningococcal and Type b Haemophilus Influenzal Conjugate Vaccine NCT01580033 | Jiangsu Province Centers for Disease Control and Prevention | Phase 3 |
| Terminated | Daptomycin in Pediatric Patients With Bacterial Meningitis NCT01522105 | Insel Gruppe AG, University Hospital Bern | Phase 1 |
| Terminated | A Study of Doripenem in CerebrospinalFluid After Doripenem Administration in Pediatric Patients Less Than 1 Ye NCT01366651 | Janssen Research & Development, LLC | Phase 1 |
| Completed | Study of a Single Dose of Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine (SP284) in Japanese NCT01519713 | Sanofi Pasteur, a Sanofi Company | Phase 3 |
| Unknown | Safety and Immunogenicity of 10-valent and 13-valent Pneumococcal Conjugate Vaccines in Papua New Guinean Chil NCT01619462 | Papua New Guinea Institute of Medical Research | Phase 3 |
| Completed | Study of a Single Dose of Menactra® Vaccine 4-6 Years After Prior Menactra Vaccine NCT01442675 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Completed | Study of Sanofi Pasteur and Lanzhou Institute's Meningococcal (Group A and C) Polysaccharide Vaccine in Childr NCT01430611 | Sanofi Pasteur, a Sanofi Company | Phase 4 |
| Completed | Post-licensure Safety Surveillance Study of Menactra Vaccine When Administered As a 2-dose Schedule to Childre NCT01689155 | Sanofi Pasteur, a Sanofi Company | — |
| Completed | Study of Two Doses of Menactra® or One Dose of Monovalent Meningococcal Group C Vaccine With Routine Immunizat NCT01359449 | Sanofi Pasteur, a Sanofi Company | Phase 3 |
| Completed | A Trial to Assess the Safety, Tolerability and Immunogenicity of Repevax and rLP2086 Vaccine When Given Togeth NCT01323270 | Pfizer | Phase 2 |
| Completed | Validation of Vital Signs and Symptoms for the Diagnosis of Serious Infections in Children in the Paediatric A NCT01396798 | KU Leuven | — |
| Completed | Post-Marketing Safety Study of Menactra® in Healthy Children, Adolescents, and Adults in the Philippines NCT01270503 | Sanofi Pasteur, a Sanofi Company | Phase 4 |
| Completed | Antibody Persistence and Response to Re-vaccination With Either Menactra® or Menomune® 3 Years After Initial V NCT01239043 | Sanofi | Phase 2 |
| Completed | A Study of Meningococcal Vaccine, Menactra® in Healthy Subjects in India NCT01086969 | Sanofi | Phase 3 |
| Terminated | Cerebrospinal Fluid Pharmacokinetics of Daptomycin NCT01025271 | University of Pittsburgh | N/A |
| Completed | Study on the Impact of Vaccination With a Conjugate Vaccine on Meningococcal Carriage NCT01119482 | London School of Hygiene and Tropical Medicine | Phase 4 |
| Completed | Risk Factors and Outcomes in Patients Treated in Neurocritical Care NCT07052656 | Karolinska Institutet | — |
| Completed | A Study of a Quadrivalent Meningococcal Tetanus Protein Conjugate Vaccine in Infants and Toddlers NCT01049035 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Completed | Understanding the Immune Response to Meningitis Vaccines NCT00901940 | University of Oxford | Phase 3 |
| Terminated | Treatment of West Nile Virus With MGAWN1 NCT00927953 | MacroGenics | Phase 2 |
| Completed | Study to Evaluate the Safety of Novartis MenACWY Conjugate Vaccine When Administered With Routine Infant Vacci NCT00806195 | Novartis | Phase 3 |
| Completed | Persistence of Bactericidal Antibodies in Adolescents and Adults Who Had Received a Single Dose of Menactra® V NCT00862277 | Sanofi Pasteur, a Sanofi Company | — |
| Completed | Procalcitonin Level and Kinetics in Children With Bacterial Infections NCT00714402 | Shaare Zedek Medical Center | — |
| Completed | Dose Comparison Study of Menactra® in US Children NCT00700635 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Completed | Antibody Persistence and Booster Dose Response in Subjects Who Received Menactra® Three Years Earlier in Study NCT00700713 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Completed | Safety and Immunogenicity of a Quadrivalent Meningococcal Tetanus Protein Conjugate Vaccine in Toddlers NCT00631995 | Sanofi Pasteur, a Sanofi Company | Phase 1 |
| Completed | Immunology and Safety of Menactra® in Children in Saudi Arabia NCT00539032 | Sanofi Pasteur, a Sanofi Company | Phase 3 |
| Completed | Safety of and Immune Response to a Meningitis Vaccine in HIV-Infected Children and Youth NCT00459316 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 1 / Phase 2 |
| Completed | Cotrimoxazole Versus Vancomycin for Invasive Methicillin-resistant Staphylococcus Aureus Infections NCT00427076 | Rabin Medical Center | Phase 3 |
| Completed | Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing Enterocolitis NCT00707785 | Johns Hopkins University | Phase 3 |
| Terminated | Colombia Epidemiologic Surveillance Study NCT00428051 | Pfizer | — |
| Completed | Effect of Meningococcal Conjugate Vaccine on Meningococcal Carriage NCT00119080 | Centers for Disease Control and Prevention | Phase 4 |
| Completed | Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 003 NCT01661751 | Hualan Biological Engineering, Inc. | Phase 3 |
| Completed | Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 002 NCT01661738 | Hualan Biological Engineering, Inc. | Phase 2 |
| Completed | Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 001 NCT01661725 | Hualan Biological Engineering, Inc. | Phase 1 |
| Completed | Concomitant Use of Gardasil (V501) (Human Papillomavirus [Types 6, 11, 16, 18] Recombinant Vaccine) With Combi NCT00325130 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | Persistence of Antibodies in Children Aged 7 to 15 Years Who Previously Received One Dose of Menactra® or Meno NCT00258856 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Completed | Persistence of Antibodies in Adolescents and Adults 15 to 23 Years Who Received One Dose of Menactra® or Menom NCT00269477 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Recruiting | Lebanese Interhospital Pneumococcal Surveillance Program NCT00901602 | American University of Beirut Medical Center | — |
| Completed | 36-Month Post-marketing Surveillance and Analysis of Menactra Vaccine in 2-10 Year Olds NCT00728260 | Sanofi Pasteur, a Sanofi Company | — |
| Completed | Descriptive, Post-marketing, Surveillance Safety Study of Menactra Vaccine NCT00254995 | Sanofi Pasteur, a Sanofi Company | — |
| Completed | Neonatal Immunization With Pneumococcal Conjugate Vaccine in Papua New Guinea NCT00219401 | Papua New Guinea Institute of Medical Research | Phase 2 |
| Completed | Study of Menactra® in US Adolescents When Administered Concomitantly With Tdap Vaccine NCT00777257 | Sanofi Pasteur, a Sanofi Company | Phase 4 |
| Completed | Study of a Tetravalent Meningococcal Diphtheria Toxoid Conjugate Vaccine in Toddlers 9 to 18 Months of Age NCT00643916 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Terminated | Does Static Ultrasound-Preview Reduce the Incidence of Difficult Lumbar Puncture? NCT00317382 | St. Luke's-Roosevelt Hospital Center | N/A |
| Completed | Impact of Daily Zinc Supplementation to Infants Born With Low Birth Weight on Death and Severe Disease NCT00495690 | Society for Applied Studies | Phase 3 |
| Completed | Study of a Booster Dose of Meningococcal Diphtheria Toxoid Conjugate Vaccine in Adolescents NCT00777790 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Terminated | Antibody Responses Following Meningococcal Tetravalent (A, C, Y, and W-135) Conjugate Vaccination in Healthy A NCT00772629 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Completed | Study of Antibody Responses After a Dose of Tetravalent Meningococcal Diphtheria Conjugate Vaccine in Children NCT00771849 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Completed | Study of Reduced Dose of Menomune® in Children Who Previously Received Meningococcal Diphtheria Toxoid Conjuga NCT00772070 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Completed | Immunogenicity of 7-Valent Pneumococcal Conjugate Vaccine in Lung Fluid of Adults With and Without HIV Infecti NCT00371878 | Royal Liverpool University Hospital | Phase 4 |
| Completed | Safety and Immunogenicity of Intradermal Versus Subcutaneous Doses of Menomune® NCT00850603 | Sanofi Pasteur, a Sanofi Company | Phase 4 |
| Terminated | Intrathecal Gemcitabine to Treat Neoplastic Meningitis, IT Gemcitabine NCT00074607 | Baylor College of Medicine | Phase 1 |
| Completed | Pneumococci and Hib Vaccination After Neurotrauma or Neurosurgery NCT02806284 | Uppsala University | Phase 2 |
| Recruiting | National Bacterial Meningitis Study NCT04664569 | Association Clinique Thérapeutique Infantile du val de Marne | — |
| Completed | Open, Non-Comparative Study of Fluconazole in Patients With Coccidioidal Meningitis NCT00002010 | Pfizer | N/A |