| Not Yet Recruiting | Biological and Clinical Underpinnings of Postoperative Pain - Mastectomy NCT07271589 | University of Alabama at Birmingham | — |
| Recruiting | Same-Day Awake Mastectomy With Immediate Breast Reconstruction for Patients With Breast Cancer NCT07510698 | University of Rome Tor Vergata | N/A |
| Not Yet Recruiting | Comparison of Serratus Posterior Superior Intercostal Plane Block and Rhomboid Intercostal Block for Postopera NCT07536867 | Antalya City Hospital | N/A |
| Not Yet Recruiting | Selected Exercise Program on Upper Cross Syndrome Post-unilateral Mastectomy NCT07447024 | Cairo University | N/A |
| Recruiting | Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain Syndrome NCT07421427 | Cairo University | N/A |
| Not Yet Recruiting | The Role of Amnion Membrane Allografts in Nipple Preservation NCT06073808 | Stanford University | N/A |
| Recruiting | Investigation of the Effects of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plan NCT07510269 | Uludag University | N/A |
| Recruiting | Interactive Design of Patient-Specific Molds for Tissue Shaping NCT06711965 | M.D. Anderson Cancer Center | N/A |
| Completed | Effect of Patient-Anesthesiologist Gender Concordance and Analgesia Method on Postoperative Pain in Mastectomy NCT07035275 | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital | — |
| Not Yet Recruiting | Effect of Kinetic Control Exercise on Shoulder Dysfunction Post Mastectomy NCT07023913 | Cairo University | N/A |
| Recruiting | A Bionic Breast Project Using Neuroprosthesis to Reduce Chronic Pain After Mastectomy NCT06382272 | University of Chicago | N/A |
| Enrolling By Invitation | Compassion, Social Support, Flexibility, and Resilience Program for Women Surviving Breast Cancer NCT06982391 | Medipol University | N/A |
| Recruiting | Dexmedetomidine Versus Lidocaine Infusions as Adjuvants to General Anesthesia for Chronic Pain Management Afte NCT06910644 | Cairo University | N/A |
| Completed | Comparison of the Postoperative Analgesic Effects of SPSIPB and TPB in Mastectomy Operations NCT06789146 | Ankara Etlik City Hospital | N/A |
| Recruiting | Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Ge NCT07147166 | University of California, San Francisco | N/A |
| Not Yet Recruiting | Regional Anesthesia Techniques in Breast Surgery NCT06779656 | Xiaguang Duan | N/A |
| Recruiting | A Prospective Study of Video-assisted Exercise Program for the Breast Cancer Survivors NCT07071896 | University of California, San Diego | N/A |
| Completed | Kinesio-Taping and Chest Physiotherapy Program After Mastectomy NCT06701591 | Cairo University | N/A |
| Not Yet Recruiting | "Serratus Anterior Plane Block" Versus "Serratus Posterior Superior Plane Intercostal Plane Block" for Patient NCT06711549 | Ospedale di Camposampiero | N/A |
| Completed | Effect of Wii Fit Balance Board Games on Balance in Patients With Osteoporosis Post Mastectomy NCT07364279 | Cairo University | N/A |
| Active Not Recruiting | A Study on Pain After Breast Reconstruction NCT06627582 | Memorial Sloan Kettering Cancer Center | N/A |
| Recruiting | Affecting Factors for Chronic Pain After Mastectomy NCT06592053 | Ankara Etlik City Hospital | — |
| Completed | Ultra Phonophoresis With a Hyaluronic Acid-Containing Gel on Carpal Tunnel Syndrome Post Mastectomy. NCT06538818 | Cairo University | N/A |
| Recruiting | Preoperative vs. Pathologic Size in Breast Cancer: A Prospective Study NCT06505577 | Incheon St.Mary's Hospital | — |
| Recruiting | The Impact of AI- Supported Education in Mastectomy Patient NCT06796166 | Bezmialem Vakif University | N/A |
| Completed | Comparison of Postoperative Analgesic Effectiveness of Superficial and Deep Serratus Plane Blocks for Mastecto NCT06438211 | TC Erciyes University | N/A |
| Completed | Chronic Pain in Post-Mastectomy Patients; The Difference Between Pectoral Nerve (PECS I-II) and Erector Spinal NCT06900842 | Hacettepe University | — |
| Recruiting | s Serratus Anterior Block for Perioperative Analgesia NCT06410378 | Zagazig University | N/A |
| Recruiting | Seroma of the Mammary Gland NCT05899387 | University Hospital Augsburg | N/A |
| Recruiting | Stellate Ganglion Block for Prevention of Post Mastectomy Depression NCT06263907 | Mansoura University | N/A |
| Completed | Effect of Emotion Freedom Technique on Perceived Stress, Resilience and Sexual Satisfaction Among Women After NCT06583629 | Helwan University | N/A |
| Completed | Effects of Rhomboid Intercostal Block on Postoperative Pain Management and Chronic Pain Incidence in Mastectom NCT06756048 | Koç University | N/A |
| Completed | Pilates Exercise Versus Proprioceptive Neuromuscular Facilitation in Shoulder Dysfunction Post Mastectomy NCT06652282 | Cairo University | N/A |
| Unknown | Combining Stellate Ganglion and T2 and T3 Radiofrequency Ablation on Post-mastectomy Complex Regional Pain Syn NCT06033456 | National Cancer Institute, Egypt | N/A |
| Recruiting | Assessment of the Interi Manifold in Implant-Based Breast Reconstruction NCT05975359 | Stanford University | N/A |
| Completed | The Role of Psychoeducation in Breast Cancer Care NCT06981910 | Dicle University | N/A |
| Completed | Serratus Anterior Plane Block Versus Erector Spinae Plane Block With Dexmedetomidine Added to Bupivacaine for NCT06737458 | Kafrelsheikh University | N/A |
| Recruiting | Impact of Nipple Reconstruction in Mastectomized Patients Using Cross-Linked Hyaluronic Acid Injection. NCT07008339 | Germans Trias i Pujol Hospital | N/A |
| Recruiting | Impact of Erector Spinae Plane Block on Chronic Postsurgical Pain in Breast Cancer Patients NCT05494502 | Peking University First Hospital | N/A |
| Terminated | Mastectomy Flap Temperature Study NCT05395936 | Wake Forest University Health Sciences | N/A |
| Completed | Web-Assisted Interactive Nurse Program in Mastectomy Patients: A Mixed Method Study NCT05222763 | Cumhuriyet University | N/A |
| Recruiting | Finding Sentinel Lymph Nodes During Mastectomy Using Indocyanine Green (INIGMA Study) NCT07362485 | Isabelle Henskens | N/A |
| Recruiting | Long-term Outcomes of Lidocaine Infusions for Post-Operative Pain (LOLIPOP) Trial NCT05072314 | Monash University | Phase 3 |
| Withdrawn | Brijjit® for Wound Closure in Gender Affirming Mastectomies NCT05368519 | NYU Langone Health | N/A |
| Completed | Effect of Aromatherapy Massage on Pain and Anxiety After Mastectomy NCT05658367 | Istanbul Medipol University Hospital | N/A |
| Completed | Comparing the Quality of Analgesia With Pectoral Nerve Block and Serratus Plane Block in Modified Radical Mast NCT05224310 | Suez Canal University | N/A |
| Unknown | The Efficacy of Ultrasound-Guided Rhomboid Intercostal Block Versus Serratus Plane Block in Mastectomy. NCT05156775 | Tanta University | N/A |
| Recruiting | A Study to Reduce Persistent Post-mastectomy Pain Using Opioid-free Anesthesia NCT05146778 | Gangnam Severance Hospital | N/A |
| Unknown | Comparison of Erector Spinae Plane Block and Pectoral Nerve Block for Acute and Chronic Pain in Mastectomies NCT05069805 | Hospital de Base | N/A |
| Completed | Music Intervention for Preoperative Anxiety and Acute Pain Among Mastectomy Patients NCT04824183 | Chinese University of Hong Kong | N/A |
| Unknown | Emotional Security and Quality of Life Among Breast Cancer Patient Who Have Undergo Mastectomy NCT04872803 | Assiut University | — |
| Recruiting | A Comparative Analysis of REVOLVE, LipoGrafter, and Viality in Autologous Fat Grafting During Breast Surgery NCT04891510 | Weill Medical College of Cornell University | N/A |
| Unknown | Nerve Blocks in Alloplastic Breast Reconstruction NCT04860843 | University of British Columbia | N/A |
| Recruiting | Impact of Neoadjuvant Hormonal Therapy on the Surgical Management of Extensive Ductal Carcinomas in Situ NCT04666961 | Institut Cancerologie de l'Ouest | Phase 2 |
| Recruiting | Primary Surgical Prevention of Breast Cancer-related Lymphedema NCT04687956 | Gangnam Severance Hospital | N/A |
| Completed | Feasibility of Total Mastectomy in Ambulatory Care NCT04270136 | Centre Hospitalier Universitaire, Amiens | N/A |
| Completed | EMG Biofeedback Treatment for Chronic Low Back Pain, Cancer Pain and Migraines NCT04607460 | Brigham and Women's Hospital | N/A |
| Not Yet Recruiting | Mastectomy With Retention of the Nipple-areola Complex, Robot-assisted or Not, and / or Immediate or Seconday NCT04457167 | Institut Paoli-Calmettes | N/A |
| Completed | RCT Implant Based Breast Reconstruction NCT04558138 | University of Colorado, Denver | N/A |
| Completed | Preoperative Regional Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy NCT04019834 | University of Alabama at Birmingham | EARLY_Phase 1 |
| Completed | Use of Microporous Polysaccharide Hemispheres in Breast Cancer Patients Undergoing Mastectomy NCT06824831 | Fundación para la Investigación del Hospital Clínico de Valencia | Phase 4 |
| Unknown | Erector Spina Plane Block vs Serratus Anterior Plane Block for Postoperative Mastectomy Pain NCT04296188 | Tokat Gaziosmanpasa University | N/A |
| Recruiting | Repeat Sentinel Lymph Node Biopsy in Ipsilateral Breast Tumor Recurrence NCT04741737 | Gangnam Severance Hospital | N/A |
| Completed | Paravertebral Block Versus Erector Spinae Plane Block for Modified Radical Mastectomy in Womens. NCT03614091 | Assiut University | N/A |
| Unknown | Pre-pectoral Versus Sub-pectoral Implant Placement in Immediate Breast Reconstruction NCT03959709 | Ottawa Hospital Research Institute | N/A |
| Completed | Application-Enabled Shared Decision-Making NCT04858282 | Chang Gung Memorial Hospital | N/A |
| Unknown | Effect of Dexmedetomidine on the Duration of Pain Control in ESP Block for Breast Surgery NCT04029467 | Lebanese American University | Phase 4 |
| Completed | Erector Spina Plane Block Versus Deep Serratus Anterior Plane Block for Post Mastectomy Analgesia NCT04108715 | King Saud University | N/A |
| Unknown | Post-Mastectomy Analgesia Using Exparel (Liposomal) Versus Standard Bupivacaine or Placebo NCT03504865 | Georgetown University | Phase 2 |
| Terminated | Contribution of Auriculotherapy in the Management of Mastectomy With Immediate Reconstruction by Latissimus Do NCT05126615 | Ramsay Générale de Santé | N/A |
| Completed | Evaluation of the Effects of the Couple-based Family Nursing for Women With Breast Cancer NCT05100914 | National Defense Medical Center, Taiwan | N/A |
| Withdrawn | Serratus Anterior Muscle Plane Block vsThoracic Paravertebral Block For Unilateral Mastectomies NCT02822196 | The University of Texas Health Science Center, Houston | Phase 4 |
| Terminated | Local Compression Seroma DIminution Objective (CLODIS) NCT03598712 | Centre Francois Baclesse | Phase 3 |
| Withdrawn | Sensation After Nipple Sparing Mastectomy and Breast Reconstruction With or Without Neurotized Free Tissue Tra NCT03135392 | Case Comprehensive Cancer Center | N/A |
| Terminated | Near-infrared Spectroscopy for Monitoring Tissue Oxygenation in Breast Reconstruction NCT03757793 | University Hospital, Antwerp | — |
| Completed | KİNECT® - Video Games Based Physiotherapy Programme in Patients With Breast Cancer Surgery NCT03618433 | Acibadem University | N/A |
| Completed | Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized, Double-Masked, Sham-Controlle NCT03578237 | University of California, San Diego | N/A |
| Unknown | Kinesio Tex Tape in Reducing Edema and Seroma After Complex Reconstructive Breast Surgery NCT03477565 | IRCCS San Raffaele | N/A |
| Withdrawn | Effect of Pectoralis Block on Analgesia After Simple Mastectomy NCT03143530 | Vanderbilt University Medical Center | Phase 4 |
| Completed | Evaluation of a Breast Double Block Analgesia for the Mastectomy With Radical Axillary Lymphadenectomy Surgery NCT03177733 | Maison de Santé Prostestante de Bordeaux Bagatelle | — |
| Completed | Study Evaluating the Efficacy of Loco-regional Anaesthesia PECS on Chronic Pain of a Mastectomy NCT03023007 | Centre Oscar Lambret | N/A |
| Completed | High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase After Mastectomy NCT03125941 | Rigshospitalet, Denmark | Phase 4 |
| Completed | Post-Operative Outcomes of Low Thermal Dissection vs. Traditional Electrosurgery NCT03711916 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | N/A |
| Completed | Reduction of Post Mastectomy Pain With the Jacki® Recovery Jacket NCT02976103 | Dana-Farber Cancer Institute | N/A |
| Completed | Postmastectomy Pain Syndrome in an Indian Cancer Hospital NCT03067922 | Tata Memorial Centre | — |
| Completed | Relationship of Intra-Epidermal Nerve Fibre Density (IENFD) and Structure to Chronic Post-Mastectomy Pain Synd NCT02919891 | Royal Infirmary of Edinburgh | — |
| Unknown | Opting for Breast Reconstruction After Mastectomy or Not: Search for Influencing Factors NCT03039348 | Universitair Ziekenhuis Brussel | — |
| Completed | PECS and Parasternal Block for Breast Surgery NCT03043755 | Istituti Ospitalieri di Cremona | — |
| Completed | Mastectomy in Ambulatory Breast Surgery NCT03003169 | Institut de Cancérologie de Lorraine | — |
| Completed | Comparison of Perioperative Opioid Consumption Following Pectoral Nerve Block for Breast Cancer Surgery NCT02741232 | Maisonneuve-Rosemont Hospital | N/A |
| Unknown | Ultrasound Guided Versus Standard Paravertebral Blockade in Breast Surgery NCT02623387 | University College Hospital Galway | N/A |
| Completed | Evaluation of a Human Acellular Dermal Matrix in Post Mastectomy Reconstruction NCT02263261 | Musculoskeletal Transplant Foundation | N/A |
| Completed | Single Versus Double Drains After Mastectomy NCT02202252 | Ankara Diskapi Training and Research Hospital | N/A |
| Unknown | The Use of Laser-Assisted Indocyanine Green Dye Angiography to Predict Mastectomy Skin Flap Viability NCT01554267 | Stony Brook University | N/A |
| Completed | Efficacy of Enhanced Recovery After Surgery Pathway for Total Mastectomy NCT03181139 | Monica Harbell | — |
| Unknown | PREvention of Post-mastectomy LYMphoceles by PAdding NCT02894021 | Centre Hospitalier Universitaire, Amiens | N/A |
| Unknown | Levobupivacaine Prolonged Wound Infusion for Postoperative Pain Relief After Breast Surgery NCT02035904 | Fondazione IRCCS Policlinico San Matteo di Pavia | Phase 4 |
| Completed | Lidocaine Pharmacokinetics During Tumescent Infiltrative Anaesthesia for Mastectomy NCT01687348 | Assistance Publique Hopitaux De Marseille | Phase 3 |
| Completed | Acellular Dermal Matrix in Tissue Expander Breast Reconstruction: A Prospective, Randomized, Clinical Trial Co NCT01781299 | University of Pittsburgh | Phase 4 |
| Completed | Prevention of Post-Mastectomy Breast Pain Using Ambulatory Continuous Paravertebral Blocks NCT01231204 | University of California, San Diego | Phase 4 |
| Unknown | Ultrasound vs. Predetermined Distance Techniques for Paravertebral Nerve Block in Patients Having Breast Surge NCT01217593 | Ochsner Health System | N/A |
| Completed | Breast Reconstruction and Augmentation With Brava Enhanced Autologous Fat Micro Grafting NCT00466765 | Brava | N/A |
| Completed | Reusable Versus Disposable Draping System in Breast Reconstruction Surgery NCT01176786 | Wake Forest University Health Sciences | N/A |
| Terminated | PEAK PlasmaBlade™ 4.0 Versus Traditional Electrosurgery in Mastectomy NCT00943605 | Medtronic Surgical Technologies | N/A |
| Completed | Patient Activated Controlled Expansion (PACE) Trial NCT01009008 | AirXpanders, Inc. | N/A |
| Unknown | Application Of Autologous Blood Products During Modified Radical Mastectomy NCT00802477 | Marshall University | Phase 3 |
| Completed | Registry of Mastectomy for Breast Cancer Risk Reduction NCT00555503 | Georgetown University | — |
| Terminated | The Use of an Acellular Dermal Matrix in a Two-Staged Breast Reconstruction NCT00616824 | Vanderbilt University Medical Center | Phase 4 |
| Completed | Comparison of Pain Therapeutic Effects After Benign Mastectomy NCT00519246 | Nanjing Medical University | Phase 4 |
| Unknown | Does a Single Steroid Injection Reduce the Formation of Postmastectomy Seroma NCT00307606 | Herlev Hospital | Phase 4 |