NCT00519246

Comparison of Pain Therapeutic Effects After Benign Mastectomy

Clinical Comparison of Postoperative Pain Therapeutic Effects After Benign Mastectomy

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 2,000 (actual)
• Sponsor: Nanjing Medical University · Academic / Other
• Sex: Female
• Age: 18 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

With the incremental trend of benign breast tumor, the surgical process of mastectomy was proceeded too much every day, especially in the Maternal Health Care Hospital, but whether the investigators can find another way to relieve the postoperative pain after such an operation is still unknown. The investigators hypothesized that the pain from the relatively small surgery may not be significant compared to different treatments, even if no drug was delivered to them. The investigators are enrolling patients who underwent mastectomy from benign breast tumor, and are observing the analgesic effects of different drugs.

Conditions

• Pain, Postoperative
• Mastectomy

Interventions

Type	Name	Description
DRUG	Saline	Saline 5 ml administrated intravenously
DRUG	Opioid	Butorphanol tartrate 1 mg i.v.
DRUG	Opioid	Butorphanol Tartrate 2 mg i.v.
DRUG	NSAID	Flurbiprofen Axetil 50 mg i.v.
DRUG	NSAID	Flurbiprofen Axetil 100 mg i.v.
DRUG	Opioid	Tramadol Hydrochloride 10 mg i.v.
DRUG	Opioid	Tramadol Hydrochloride 20 mg i.v.

Timeline

• Start date: 2007-02-01
• Primary completion: 2007-12-01
• Completion: 2007-12-01
• First posted: 2007-08-22
• Last updated: 2009-03-31

Locations

1 site across 1 country: China